Patents by Inventor Yoko OKABE

Yoko OKABE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200273623
    Abstract: A multilayer ceramic capacitor includes a ceramic body including a stack of dielectric layers and internal electrodes, and an external electrode electrically connected to each of the internal electrodes and provided at each of both end surfaces of the ceramic body. The external electrode includes a metal layer and a plating layer on the metal layer. In a cross section of the metal layer that is obtained by cutting the external electrode along a plane parallel to a side surface at a central position in a width direction, the metal layer includes a dielectric material at an area ratio of about 20% or more, and includes cavities at an area ratio of about 5% or more and about 20% or less, the cavities having an average diameter of about 0.5 ?m or more and about 1.5 ?m or less, and having a maximum diameter of about 5.0 ?m or less.
    Type: Application
    Filed: February 12, 2020
    Publication date: August 27, 2020
    Inventors: Takehisa SASABAYASHI, Akitaka DOI, Kotaro SHIMIZU, Yoko OKABE
  • Patent number: 10568495
    Abstract: Provided is a scanning endoscope system including: an illumination-light emitting portion that is inserted into a body of a patient and that emits illumination light emitted from a light-source portion toward an imaging subject in the body in a spot-like manner; a light scanner that scans the illumination light on the imaging subject; and a light detector that is disposed at a body surface of the patient, and that detects reflected light coming from the scanning position in the imaging subject, at which the illumination light is scanned by the light scanner.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: February 25, 2020
    Assignee: OLYMPUS CORPORATION
    Inventors: Masashi Yamada, Atsuyoshi Shimamoto, Mitsuru Namiki, Keiichiro Nakajima, Takamitsu Sakamoto, Mikihiko Terashima, Yoko Okabe, Yu Kondo
  • Patent number: 10535468
    Abstract: A method for manufacturing a multilayer ceramic capacitor includes preparing a green multilayer body including a stack of dielectric sheets printed with inner electrodes, coating the green multilayer body with a conductive paste that is connected to the inner electrodes, and firing the conductive paste and the green multilayer body at the same time, wherein a rate of temperature increase from about 800° C. to about 1,100° C. during the firing is about 15° C. per minute or more.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: January 14, 2020
    Assignee: MURATA MANUFACTURING CO., LTD.
    Inventors: Takehisa Sasabayashi, Yasuhiro Nishisaka, Satoshi Matsuno, Yoko Okabe
  • Patent number: 10214584
    Abstract: The present invention aims to provide a pharmaceutical composition for cancer treatment, which comprises a novel monoclonal antibody binding to SLC6A6 or its extracellular region and a chemotherapeutic agent conjugated therewith, as well as a therapeutic method in which the monoclonal antibody or a therapeutic agent composed of the monoclonal antibody conjugated with a chemotherapeutic agent is used in combination with a chemotherapeutic agent. The present invention provides a pharmaceutical composition comprising an antibody conjugate configured such that a monoclonal antibody having higher affinity than conventional antibodies and recognizing native SLC6A6 or a native polypeptide of an extracellular region of SLC6A6 is conjugated with an anticancer agent or the like having activity against cancer and other hyperproliferative diseases.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: February 26, 2019
    Assignee: ORDER-MADE MEDICAL RESEARCH INC.
    Inventors: Hiroyuki Satofuka, Kensuke Ohse, Shigeki Mukobata, Hirotada Akiyama, Masaya Ohtsu, Yoko Okabe, Yasufumi Murakami
  • Patent number: 10090108
    Abstract: A multilayer ceramic capacitor having an external electrode with a glass phase, where an occupation rate of the glass phase is 30% to 60% on an area ratio, and a maximum length c of the glass phase is 5 ?m or less.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: October 2, 2018
    Assignee: MURATA MANUFACTURING CO., LTD.
    Inventors: Tetsuya Kisumi, Toshiki Nagamoto, Yasuhiro Nishisaka, Yoko Okabe
  • Publication number: 20180116492
    Abstract: Provided is a scanning endoscope system including: an illumination-light emitting portion that is inserted into a body of a patient and that emits illumination light emitted from a light-source portion toward an imaging subject in the body in a spot-like manner; a light scanner that scans the illumination light on the imaging subject; and a light detector that is disposed at a body surface of the patient, and that detects reflected light coming from the scanning position in the imaging subject, at which the illumination light is scanned by the light scanner.
    Type: Application
    Filed: December 19, 2017
    Publication date: May 3, 2018
    Applicant: OLYMPUS CORPORATION
    Inventors: Masashi YAMADA, Atsuyoshi SHIMAMOTO, Mitsuru NAMIKI, Keiichiro NAKAJIMA, Takamitsu SAKAMOTO, Mikihiko TERASHIMA, Yoko OKABE, Yu KONDO
  • Publication number: 20180110402
    Abstract: Provided is a scanning endoscope system including an illumination-light emitting unit that outputs illumination light emitted from a light source in a spot-like manner toward a subject, a light scanner that scans the illumination light output from the illumination-light emitting unit over the subject, and a light detector that is provided in a movable manner relative to the illumination-light emitting unit and that detects reflection light from a scan position on the subject over which the illumination light is scanned by the light scanner.
    Type: Application
    Filed: December 12, 2017
    Publication date: April 26, 2018
    Applicant: OLYMPUS CORPORATION
    Inventors: Masashi YAMADA, Atsuyoshi SHIMAMOTO, Mitsuru NAMIKI, Keiichiro NAKAJIMA, Takamitsu SAKAMOTO, Mikihiko TERASHIMA, Yoko OKABE
  • Publication number: 20180108483
    Abstract: A method for manufacturing a multilayer ceramic capacitor includes preparing a green multilayer body including a stack of dielectric sheets printed with inner electrodes, coating the green multilayer body with a conductive paste that is connected to the inner electrodes, and firing the conductive paste and the green multilayer body at the same time, wherein a rate of temperature increase from about 800° C. to about 1,100° C. during the firing is about 15° C. per minute or more.
    Type: Application
    Filed: October 16, 2017
    Publication date: April 19, 2018
    Inventors: Takehisa SASABAYASHI, Yasuhiro NISHISAKA, Satoshi MATSUNO, Yoko OKABE
  • Publication number: 20170313770
    Abstract: The present invention provides a reagent for detection or diagnosis of cancer, which comprises a monoclonal antibody against MCT5 or a fragment thereof.
    Type: Application
    Filed: October 1, 2015
    Publication date: November 2, 2017
    Applicant: ORDER-MADE MEDICAL RESEARCH INC.
    Inventors: Hiroyuki SATOFUKA, Yoko OKABE
  • Publication number: 20170221635
    Abstract: A multilayer ceramic capacitor having an external electrode with a glass phase, where an occupation rate of the glass phase is 30% to 60% on an area ratio, and a maximum length c of the glass phase is 5 ?m or less.
    Type: Application
    Filed: April 11, 2017
    Publication date: August 3, 2017
    Inventors: Tetsuya Kisumi, Toshiki Nagamoto, Yasuhiro Nishisaka, Yoko Okabe
  • Patent number: 9667174
    Abstract: A ceramic electronic component includes a ceramic body, inner electrodes, a glass coating layer, and outer electrodes. The glass coating layer extends from an exposed portion of one of the inner electrodes at a first end surface to a first principal surface. The outer electrodes are each constituted by a plating film disposed directly above the glass coating layer. The glass coating layer includes a glass medium and metal powder particles that define conductive paths. The metal powder particles have an elongated or substantially elongated shape and are dispersed in the glass medium. The dimension of a portion of the glass coating layer located on the first principal surface in the length direction, is larger than that of a portion of the glass coating layer located on the first end surface in the thickness direction.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: May 30, 2017
    Assignee: MURATA MANUFACTURING CO., LTD.
    Inventors: Yasuhiro Nishisaka, Satoshi Matsuno, Tetsuya Kisumi, Yoko Okabe
  • Patent number: 9653211
    Abstract: A conductive paste includes a metal powder, a glass frit containing a Si component, and an organic vehicle. The metal powder has a flat shape with a ratio a/b of a maximum length a to a maximum thickness b of 2.5 or more, a molar content of SiO2 in the glass frit is 36 to 59 percent by mole, and a volume content of the glass frit is 6 to 11 percent by volume. In external electrodes of a multilayer ceramic capacitor using this conductive paste, the molar content of SiO2 in a glass phase is 38 to 60 percent by mole, and an occupation rate of the glass phase is 30% to 60% on the area ratio, and a maximum length c of the glass phase is 5 ?m or less.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: May 16, 2017
    Assignee: MURATA MANUFACTURING CO., LTD.
    Inventors: Tetsuya Kisumi, Toshiki Nagamoto, Yasuhiro Nishisaka, Yoko Okabe
  • Publication number: 20160333092
    Abstract: The present invention aims to provide a pharmaceutical composition for cancer treatment, which comprises a novel monoclonal antibody binding to SLC6A6 or its extracellular region and a chemotherapeutic agent conjugated therewith, as well as a therapeutic method in which the monoclonal antibody or a therapeutic agent composed of the monoclonal antibody conjugated with a chemotherapeutic agent is used in combination with a chemotherapeutic agent. The present invention provides a pharmaceutical composition comprising an antibody conjugate configured such that a monoclonal antibody having higher affinity than conventional antibodies and recognizing native SLC6A6 or a native polypeptide of an extracellular region of SLC6A6 is conjugated with an anticancer agent or the like having activity against cancer and other hyperproliferative diseases.
    Type: Application
    Filed: January 15, 2015
    Publication date: November 17, 2016
    Applicant: ORDER-MADE MEDICAL RESEARCH INC.
    Inventors: Hiroyuki SATOFUKA, Kensuke OHSE, Shigeki MUKOBATA, Hirotada AKIYAMA, Masaya OHTSU, Yoko OKABE, Yasufumi MURAKAMI
  • Patent number: 9328014
    Abstract: A ceramic electronic component includes a ceramic body, a glass coating layer, and terminal electrodes. End portions of inner electrodes are exposed at a surface of the ceramic body. The glass coating layer covers portions of the ceramic body in which the inner electrodes are exposed. The terminal electrodes are disposed directly above the glass coating layer and are each constituted by a plating film. The glass coating layer includes a glass medium and metal powder particles that are dispersed in the glass medium and define conductive paths which electrically connect the inner electrodes and the terminal electrodes. The metal powder particles include first metal powder particles and second metal powder particles. The first metal powder particles are flat or substantially flat powder particles. The second metal powder particles are spherical or substantially spherical powder particles.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: May 3, 2016
    Assignee: Murata Manufacturing Co., Ltd.
    Inventors: Yasuhiro Nishisaka, Satoshi Matsuno, Tetsuya Kisumi, Yoko Okabe
  • Publication number: 20160009799
    Abstract: The object of the present invention is to prepare a cancer therapeutic agent by means of a novel monoclonal antibody which binds to SLC6A6 or its extracellular region and a substance which suppresses SLC6A6 expression. The present invention provides a pharmaceutical composition comprising a monoclonal antibody which recognizes native SLC6A6 or a polypeptide in the extracellular region of SLC6A6.
    Type: Application
    Filed: March 6, 2013
    Publication date: January 14, 2016
    Applicant: ORDER-MADE MEDICAL RESEARCH INC.
    Inventors: Hiroyuki SATOFUKA, Kensuke OHSE, Shigeki MUKOBATA, Yumiko KATO, Yoko OKABE, Yasuhiro MATSUMURA, Masahiro YASUNAGA
  • Publication number: 20140347783
    Abstract: A conductive paste includes a metal powder, a glass frit containing a Si component, and an organic vehicle. The metal powder has a flat shape with a ratio a/b of a maximum length a to a maximum thickness b of 2.5 or more, a molar content of SiO2 in the glass frit is 36 to 59 percent by mole, and a volume content of the glass frit is 6 to 11 percent by volume. In external electrodes of a multilayer ceramic capacitor using this conductive paste, the molar content of SiO2 in a glass phase is 38 to 60 percent by mole, and an occupation rate of the glass phase is 30% to 60% on the area ratio, and a maximum length c of the glass phase is 5 ?m or less.
    Type: Application
    Filed: August 12, 2014
    Publication date: November 27, 2014
    Inventors: Tetsuya Kisumi, Toshiki Nagamoto, Yasuhiro Nishisaka, Yoko Okabe
  • Publication number: 20140292141
    Abstract: A ceramic electronic component includes a ceramic body, inner electrodes, a glass coating layer, and outer electrodes. The glass coating layer extends from an exposed portion of one of the inner electrodes at a first end surface to a first principal surface. The outer electrodes are each constituted by a plating film disposed directly above the glass coating layer. The glass coating layer includes a glass medium and metal powder particles that define conductive paths. The metal powder particles have an elongated or substantially elongated shape and are dispersed in the glass medium. The dimension of a portion of the glass coating layer located on the first principal surface in the length direction, is larger than that of a portion of the glass coating layer located on the first end surface in the thickness direction.
    Type: Application
    Filed: February 27, 2014
    Publication date: October 2, 2014
    Applicant: MURATA MANUFACTURING CO., LTD.
    Inventors: Yasuhiro NISHISAKA, Satoshi MATSUNO, Tetsuya KISUMI, Yoko OKABE
  • Publication number: 20140292142
    Abstract: A ceramic electronic component includes a ceramic body, a glass coating layer, and terminal electrodes. End portions of inner electrodes are exposed at a surface of the ceramic body. The glass coating layer covers portions of the ceramic body in which the inner electrodes are exposed. The terminal electrodes are disposed directly above the glass coating layer and are each constituted by a plating film. The glass coating layer includes a glass medium and metal powder particles that are dispersed in the glass medium and define conductive paths which electrically connect the inner electrodes and the terminal electrodes. The metal powder particles include first metal powder particles and second metal powder particles. The first metal powder particles are flat or substantially flat powder particles. The second metal powder particles are spherical or substantially spherical powder particles.
    Type: Application
    Filed: February 27, 2014
    Publication date: October 2, 2014
    Applicant: Murata Manufacturing Co., Ltd.
    Inventors: Yasuhiro NISHISAKA, Satoshi MATSUNO, Tetsuya KISUMI, Yoko OKABE