Patents by Inventor Yolanda Gasanz Guilen

Yolanda Gasanz Guilen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the Preparation of Optically Active Derivatives of 2-(2-Pyridylmethylsulfinyl)-Benzimidazole Via Inclusion Complex with 1,1'-Binaphthalene-2, 2'Diol
    Publication number: 20080167473
    Abstract: Process for the preparation of optically active derivatives of 2-(2-piridylmethylsulfinyl)-benzimidazole, or salts thereof, by resolution of the corresponding racemic derivatives of 2-(2-piridylmethylsulfinyl)-benzimidazole. The resolution is performed through the formation of inclusion complexes with (S)-(?) or (R)-(+)-[1,1?-Binaphthalene]-2,2?-diol in the presence of an amine, followed by the break of the inclusion complex by treatment with an hydroxide of an alkaline metal. The enantiomer of the derivative of 2-(2-piridylmethylsulfinyl)-benzimidazole may be obtained by extractions at a particular pH with a suitable organic solvent. The process allows to perform the resolution with high yields and high optical purity, without using neither toxic solvents nor chromatography.
    Type: Application
    Filed: February 22, 2006
    Publication date: July 10, 2008
    Applicant: ESTEVE QUÃMICA, S.A.
    Inventors: Laura Coppi, Ramon Berenguer Maimo, Yolanda Gasanz Guilen, Jorge Medrano Ruperez