Patents by Inventor Yolande Rouiller

Yolande Rouiller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell culture methods for increased cell viability
    Patent number: 11254964
    Abstract: The present invention relates to a method of maintaining cell viability at a level of at least 80% for up to 14 days in a fed-batch culture of cells producing a recombinant protein, the method comprising maintaining the cell culture medium at a pH of 6.5 to 7.0 and at a temperature of 31° C. to 35° C. for at least 5 consecutive days of the duration of the cell culture method.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: February 22, 2022
    Assignee: FRESENIUS KABI DEUTSCHLAND GMBH
    Inventors: Matthieu Stettler, Hervé Broly, Thomas Solacroup, Yolande Rouiller
  • Medium for high performance mammalian fed-batch cultures
    Patent number: 10138467
    Abstract: The present invention relates to new serum- and protein-free culture media. These media are high performance culture media, which notably improve mammalian fed-batch cultures. The present invention also relates to methods for preparing and/or designing the medium, and methods of use thereof.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: November 27, 2018
    Assignee: ARES TRADING S.A.
    Inventors: Herve Broly, Matthieu Stettler, Martin Jordan, Arnaud Perilleux, Yolande Rouiller
  • NEW MEDIUM FOR HIGH PERFORMANCE MAMMALIAN FED-BATCH CULTURES
    Publication number: 20160264940
    Abstract: The present invention relates to new serum- and protein-free culture media. These media are high performance culture media, which notably improve mammalian fed-batch cultures. The present invention also relates to methods for preparing and/or designing the medium, and methods of use thereof.
    Type: Application
    Filed: April 3, 2014
    Publication date: September 15, 2016
    Inventors: HERVE BROLY, MATTHIEU STETTLER, MARTIN JORDAN, ARNAUD PERILLEUX, YOLANDE ROUILLER
  • Process for the production of tumor necrosis factor-binding proteins
    Publication number: 20070099266
    Abstract: The invention provides methods for increasing the recombinant production of polypeptides, in particular Tumor Necrosis Factor Binding Proteins, from mammalian cells at a temperature below 30° C.
    Type: Application
    Filed: December 21, 2004
    Publication date: May 3, 2007
    Applicant: Applied Research Systems ARS Holding N.V.
    Inventor: Yolande Rouiller