Patents by Inventor Yolandi Van der Merwe

Yolandi Van der Merwe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ocular applications of matrix bound vesicles (MBVs)
    Patent number: 11638724
    Abstract: Methods are disclosed herein for increasing retinal ganglion cell survival in a subject in need thereof. These methods include selecting a subject in need of increased retinal ganglion cell survival and administering a therapeutically effective amount of isolated nanovesicles derived from an extracellular matrix (MBVs) to the subject.
    Type: Grant
    Filed: May 4, 2018
    Date of Patent: May 2, 2023
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Stephen F. Badylak, Anne E. Faust, George S. Hussey, Yolandi Van der Merwe, Michael Brandt Steketee
  • Devices and methods for local delivery of tacrolimus
    Patent number: 11529318
    Abstract: Devices for local delivery of tacrolimus or a derivative thereof are provided, wherein the devices comprise a polymeric matrix containing tacrolimus or a derivative thereof that provides for delayed and extended release of tacrolimus or a derivative thereof. The devices can locally deliver tacrolimus or a derivative thereof to injured nervous system tissue upon implantation in a subject. Thus, techniques for local delivery of tacrolimus or a derivative thereof and methods of treatment using such devices are also provided.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: December 20, 2022
    Assignees: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Kia M. Washington, William R. Wagner, Michael Brandt Steketee, Yolandi Van der Merwe, Xinzhu Gu
  • OCULAR APPLICATIONS OF MATRIX BOUND VESICLES (MBVS)
    Publication number: 20210137988
    Abstract: Methods are disclosed herein for increasing retinal ganglion cell survival in a subject in need thereof. These methods include selecting a subject in need of increased retinal ganglion cell survival and administering a therapeutically effective amount of isolated nanovesicles derived from an extracellular matrix (MBVs) to the subject.
    Type: Application
    Filed: May 4, 2018
    Publication date: May 13, 2021
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Stephen F. Badylak, Anne E. Faust, George S. Hussey, Yolandi Van der Merwe, Michael Brandt Steketee
  • DEVICES AND METHODS FOR LOCAL DELIVERY OF TACROLIMUS OR DERIVATIVES THEREOF
    Publication number: 20180369160
    Abstract: Devices for local delivery of tacrolimus or a derivative thereof are provided, wherein the devices comprise a polymeric matrix containing tacrolimus or a derivative thereof that provides for delayed and extended release of tacrolimus or a derivative thereof. The devices can locally deliver tacrolimus or a derivative thereof to injured nervous system tissue upon implantation in a subject. Thus, techniques for local delivery of tacrolimus or a derivative thereof and methods of treatment using such devices are also provided.
    Type: Application
    Filed: June 18, 2018
    Publication date: December 27, 2018
    Applicants: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Kia M. Washington, William R. Wagner, Michael Brandt Steketee, Yolandi Van der Merwe, Xinzhu Gu