Patents by Inventor Yona Tadir

Yona Tadir has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240057935
    Abstract: Internal cervical exams during labor pose multiple challenges, including infection risk, subjectivity, invasiveness, and discomfort. A monitoring system described herein enables non-invasive and accurate measurement of cervical dilation and assessment of the baby's station. By inserting a narrow linear ultrasound probe through the working channel, high-resolution ultrasound images of the cervix can be obtained, eliminating the need for painful and subjective exams, reducing infection risk, and enhancing patient comfort. Moreover, the ultrasound capability allows for potential monitoring of maternal and fetal blood oxygenation levels, providing a comprehensive picture of fetal well-being.
    Type: Application
    Filed: August 21, 2023
    Publication date: February 22, 2024
    Inventors: Lourdes Swentek, Thomas Milner, Nitesh Katta, Yona Tadir
  • Publication number: 20230125467
    Abstract: The present invention features a method for automated image-based prediction of physiologic and pathologic conditions of a vaginal wall of a patient using optical coherence tomography. In some embodiments, the method may comprise capturing, by a functional optical coherence tomography imaging probe, one or more images of the vaginal wall. The method may further comprise constructing a computing device a visualization of the vaginal wall, discretizing the visualization of the vaginal wall in to a discrete model, measuring a plurality of objective attributes from the discrete model, generating, based on the plurality of objective attributes, a Vaginal Health Index (VHI), generating an associated risk value based on the VHI and a plurality of patient attributes, reconstructing the visualization of the vaginal wall based on the associated risk value, and mapping the associated risk value to the visualization of the vaginal wall such that one or more at-risk areas are highlighted.
    Type: Application
    Filed: November 18, 2022
    Publication date: April 27, 2023
    Inventors: Zhongping Chen, Yusi Miao, Yan Li, Bruce J. Tromberg, Yona Tadir
  • Patent number: 11517194
    Abstract: An in vivo optical biopsy applicator of the vaginal wall for treatment planning, monitoring, and imaging guided therapy is described herein. The applicator may include an imaging probe operatively coupled to a laser ablation device. The applicator allows for non-invasive optical tissue monitoring in order to define pre- and post menopausal parameters, pre- and post-treatment microscopic changes, and offers an objective scientific tool in order to compare currently available medical, non-medicated, and energy-based treatment protocols.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: December 6, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Zhongping Chen, Yusi Miao, Yan Li, Bruce J. Tromberg, Yona Tadir
  • Publication number: 20190200851
    Abstract: An in vivo optical biopsy applicator of the vaginal wall for treatment planning, monitoring, and imaging guided therapy is described herein. The applicator may include an imaging probe operatively coupled to a laser ablation device. The applicator allows for non-invasive optical tissue monitoring in order to define pre- and post menopausal parameters, pre- and post-treatment microscopic changes, and offers an objective scientific tool in order to compare currently available medical, non-medicated, and energy-based treatment protocols.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 4, 2019
    Inventors: Zhongping Chen, Yusi Miao, Yan Li, Bruce J. Tromberg, Yona Tadir
  • Patent number: 5478339
    Abstract: An improved device for delivery of photoenergy from a light source, such as a laser, into a uterine cavity for photodynamic therapy is comprised of a plurality of optic fibers, which are bundled together and inserted into the uterine cavity by means of a uterine cannula. The cannula is positioned within the uterine cavity at a preferred location and then withdrawn thereby allowing the plurality of optic fibers to splay or diverge one from the other within the cavity. Different portions of the distal tip of the optic fiber is provided with a light diffusing tip, the remainder being provided with a nondiffusing tip portion. The fiber optic shape, as well as the segment which is permitted to actively diffuse light through the tip, is selected in order to provide a more uniform exposure intensity of the photo energy or at least sufficient radiation directed to each segment of the uterine walls.
    Type: Grant
    Filed: August 30, 1994
    Date of Patent: December 26, 1995
    Assignee: The Regents of the University of California
    Inventors: Yona Tadir, Michael W. Berns, Lars O. Svaasand, Bruce J. Tromberg
  • Patent number: 5458595
    Abstract: An improved vaginal speculum for photodynamic therapy of intraepithelial tissue and in particular vaginal, cervical and vulvar neoplasia utilizes a precisely and accurately positionable optic fiber through which a predetermined dose of light in the range of 620 to 700 nanometers is delivered over a controlled area which has been previously treated with photodynamic therapeutic substances. In particular, the neoplastic area has been treated with hematoporphyrin derivatives and other photosensitizers which are selectively taken into the cancerous tissue. Exposure to the appropriate wavelength laser light photoactivates the absorbed hematoporphyrins causing the release of singlet oxygen which internally oxidizes and ultimately causes cell death.
    Type: Grant
    Filed: December 16, 1993
    Date of Patent: October 17, 1995
    Assignee: The Regents of the University of California
    Inventors: Yona Tadir, Michael W. Berns, Brad J. Monk, Glen Profeta, Bruce J. Tromberg