Patents by Inventor Yonatan CHEMLA

Yonatan CHEMLA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Highly efficient and tunable system for the incorporation of unnatural amino acids into proteins in
    Patent number: 12163173
    Abstract: The present invention provides a composition with a cell having an orthogonal translation system, and an expression vector. The invention also provides a method of producing a protein carrying an unnatural amino acid, and a kit for use in producing a protein carrying the unnatural amino acid.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: December 10, 2024
    Assignees: B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY, REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Lital Alfonta, Vincent Noireaux, Orr Schlesinger, Yonatan Chemla, Eden Ozer
  • PREDICTION, BIOSYNTHESIS, AND INTEGRATION AS BIOSENSORS OF MOLECULES WITH UNIQUE LIGHT ABSORBANCE SIGNATURES AND THEIR SUBSEQUENT IN-FIELD REMOTE DETECTION USING MULTI OR HYPER-SPECTRAL CAMERAS
    Publication number: 20230183677
    Abstract: Disclosed herein are biosensors that are hyperspectral reporters. The biosensors are useful for detecting information about the environment and environmental conditions in a number of fields including agriculture. Also provided are methods of making and using the biosensors.
    Type: Application
    Filed: October 7, 2022
    Publication date: June 15, 2023
    Applicant: Massachusetts Institute of Technology
    Inventors: Christopher A. Voigt, Yonatan Chemla, Itai Levin
  • RIBOSOME TERMINATION STRUCTURES AND USE THEREOF
    Publication number: 20220396801
    Abstract: Nucleic acid molecule and vectors comprising regions of high or low folding energy are provided. Methods of producing coding sequences optimized for protein expression comprising introducing a mutation that increases or decreased folding energy are also provided.
    Type: Application
    Filed: July 21, 2022
    Publication date: December 15, 2022
    Inventors: Tamir TULLER, Michael PEERI, Yonatan CHEMLA, Lital ALFONTA
  • HIGHLY EFFICIENT AND TUNABLE SYSTEM FOR THE INCORPORATION OF UNNATURAL AMINO ACIDS INTO PROTEINS IN ESCHERICHIA COLI
    Publication number: 20190330672
    Abstract: The present invention provides a composition with a cell having an orthogonal translation system, and an expression vector. The invention also provides a method of producing a protein carrying an unnatural amino acid, and a kit for use in producing a protein carrying the unnatural amino acid.
    Type: Application
    Filed: November 9, 2017
    Publication date: October 31, 2019
    Inventors: Lital ALFONTA, Vincent NOIREAUX, Orr SCHLESINGER, Yonatan CHEMLA, Eden OZER
  • GENETICALLY EXPANDED CELL FREE PROTEIN SYNTHESIS SYSTEMS, METHODS AND KITS
    Publication number: 20170292139
    Abstract: This invention relates to methods of producing a rare amino acid- or non-natural amino acid-containing protein in a cell free protein synthesis system and kits for use in and for accomplishing same. Specifically, the methods comprise the steps of expressing at least one orthogonal suppressor tRNA (o-tRNA)/aminoacyl-tRNA synthetase (aaRS) pair or derivatives thereof specific for incorporation of a rare amino acid- or non-natural amino acid in an E. coli organism; preparing a lysate of said E.
    Type: Application
    Filed: June 17, 2015
    Publication date: October 12, 2017
    Applicant: B.G NEGEV TECHNOLOGIES AND APPLICATIONS LTD., at BEN-GURION UNIVERSITY
    Inventors: Lital ALFONTA, Yonatan CHEMLA, Eden OZER