Abstract: The present disclosure discloses a tobacco leaf foliar spraying substance for reducing harmful ingredients in cheroot, a method for reducing carcinogenic components in flue-cured tobacco leaves and flue-cured tobacco shreds. The tobacco leaf foliar spraying substance contains a lotus leaf extract, the harmful chemical ingredients comprise N-nitrosonornicotine, 4-(N-methyl-nitrosamine)-1-(3-pyridinyl)-1-butanone, N-nitrosoanabasine and N-nitrosoanatabine. Foliar spraying is performed on a fertile field by using the lotus leaf extract before tobacco leaves are harvested and modulated, which not only significantly promotesagronomic characters and economic traits of tobacco and alleviates tobacco leaf browning but also effectively reduces harmful chemical ingredients unique to tobacco leaves, such as nitrosamine and nicotine.

Abstract: A method for determining tobacco-specific nitrosamines (TSNAs) in cigarette smoke using one-step clean-up coupled with LC-MS/MS is provided, including the following steps: collecting a particulate matter of mainstream cigarette smoke with a Cambridge filter pad, mixing the particulate matter of mainstream cigarette smoke, an internal standards solution and water in a 50 mL plastic centrifuge tube, and vortexing the resulting mixture at room temperature to allow extraction; transferring an extraction solution after filtration to a new centrifuge tube, adding dichloromethane, and vortexing the resulting mixture; centrifuging to collect a dichloromethane extraction solution in a lower layer to another centrifuge tube, and placing the centrifuge tube in a water bath to remove dichloromethane; dissolving the resulting extraction solution in water, and transferring the resulting solution to an autosampler vial for LC-MS/MS analysis.

Abstract: A method for determining tobacco-specific nitrosamines (TSNAs) in tobacco using one-step clean-up coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) is provided, including the following steps: destemming flue-cured tobacco or sun-cured tobacco, drying, milling, and passing through a sieve; mixing the resulting tobacco, an internal standards solution and water in a plastic centrifuge tube, and vortexing the resulting mixture at room temperature to allow extraction; transferring an extraction solution after filtration to a new centrifuge tube, adding dichloromethane, and vortexing the resulting mixture; centrifuging to collect a dichloromethane extraction solution in a lower layer to another centrifuge tube, and placing the centrifuge tube in a water bath to remove dichloromethane; dissolving the resulting extraction solution in water, and transferring the resulting solution to an autosampler vial for LC-MS/MS analysis.

Abstract: Described is a free DNA-based disease prediction model and a construction method therefor and an application thereof. The construction method includes the steps of: 1) obtaining sequencing data of free DNA samples of diseased individuals and control individuals, the number of the diseased individuals and the number of the control individuals being both multiple; 2) selecting, according to the coverage of the sequencing data of the free DNA samples of the diseased individuals and the control individuals on a genome, a gene set having a difference in the coverage of a transcription initiation site region between the diseased individuals and the control individuals; and 3) for genes in the gene set, using the coverage of the sequencing data on the gene transcription initiation site region as an input prediction model for training so as to establishing a disease prediction model.

Abstract: An assembly and an apparatus for machining a mechanical part. The assembly includes a parallel robot configured to be mounted onto an end flange of a joint robot. The parallel robot is configured to drive the servo spindle to translate along the one or more axes with respect to the parallel robot. During the machining of the mechanical part, the joint robot can stay stationary for a specific machining position of the mechanical part, and the parallel robot drives the servo spindle to translate along the one or more axes. Then, the machining tool may cut out the required shapes and characteristics at the specific machining position of the mechanical part.

Abstract: The present invention relates to the field of biotechnology. A method and system of detecting fetal chromosomal abnormalities are disclosed.

Abstract: A conductive terminal, a conductive terminal assembly and a connector are provided. The conductive terminal assembly includes a casing and at least one row of conductive terminals. The at least one row of conductive terminals includes a plurality of conductive terminals arranged side by side. Each conductive terminal includes a contact arm, a contact pin, an extension part and a tenon structure. The contact arm extends along a first direction, the contact pin extends along a second direction, and the first direction is perpendicular to the second direction. The extension part is connected between the contact arm and the contact pin, and the extension part is bent and extended relative to the contact pin. The tenon structure is connected to one of the contact arm and the contact pin. The tenon structure extends in parallel along the first direction or the second direction.

Abstract: A safety relief valve for a high-pressure hydrogen cylinder is provided therein with a compression spring and an adjusting nut. The adjusting nut can move up and down to adjust the pressure of the compression spring to compress a sealing plug, so as to adjust the pressure in the hydrogen cylinder to reach an upper limit of pressure relief, which is convenient. Meanwhile, the safety relief valve is provided therein with a fusible seal. When the temperature is lower than a melting point, the fusible seal solidifies, and the sealing plug keeps a gas outlet sealed to prevent hydrogen leakage. When the temperature is higher than the melting point, the fusible seal melts. When the pressure in the hydrogen cylinder is higher than the set upper limit, the sealing plug is forced to open, and the hydrogen flows from an exhaust hole to a hydrogen collection tube.

Abstract: A safety relief valve for a high-pressure hydrogen cylinder is provided therein with a compression spring and an adjusting nut. The adjusting nut can move up and down to adjust the pressure of the compression spring to compress a sealing plug, so as to adjust the pressure in the hydrogen cylinder to reach an upper limit of pressure relief, which is convenient. Meanwhile, the safety relief valve is provided therein with a fusible seal. When the temperature is lower than a melting point, the fusible seal solidifies, and the sealing plug keeps a gas outlet sealed to prevent hydrogen leakage. When the temperature is higher than the melting point, the fusible seal melts. When the pressure in the hydrogen cylinder is higher than the set upper limit, the sealing plug is forced to open, and the hydrogen flows from an exhaust hole to a hydrogen collection tube.

Abstract: The present invention discloses a metal strip winding continuous reinforced thermoplastic composite pipe. The present invention adopts a method designed for grouping the winding metal strips to rationally distribute the winding mode of the metal strips, and at the same time, increases the hoop strength and axial strength of the pipe by using the feature of high strength of the metal strips, thereby improving the compressive capacity of the pipe; there is no bonding between the metal strip reinforcement layers, which improves the flexibility of the composite pipe and reduces the relative slippage between the metal strip layers; the production process is simple, and requirements for the equipment investment are small, thereby greatly reducing the manufacturing cost and ensuring the flexibility and seismic resistance of the pipeline.

Abstract: Methods for predicting patient deterioration or clinical events by detecting patterns in heterogeneous temporal clinical data streams that are predictive of certain clinical end points and matching the patient state with those patterns are described. The detected patterns, referred to as SuperAlarm triggers, are a predictive combination of frequently co-occurring monitor alarms, conditions and laboratory test results that can predict patient deterioration for imminent life-threatening events. SuperAlarm triggers may also exhibit patterns in the sequence of SuperAlarms that are triggered over the monitoring time of a patient. Sequential patterns of SuperAlarm triggers may also indicate a temporal process of change in patient status. SuperAlarm based alerts will also greatly reduce the number of false alarms and alarm fatigue compared to conventional alarms.

Abstract: The present invention discloses a metal strip winding continuous reinforced thermoplastic composite pipe. The present invention adopts a method designed for grouping the winding metal strips to rationally distribute the winding mode of the metal strips, and at the same time, increases the hoop strength and axial strength of the pipe by using the feature of high strength of the metal strips, thereby improving the compressive capacity of the pipe; there is no bonding between the metal strip reinforcement layers, which improves the flexibility of the composite pipe and reduces the relative slippage between the metal strip layers; the production process is simple, and requirements for the equipment investment are small, thereby greatly reducing the manufacturing cost and ensuring the flexibility and seismic resistance of the pipeline.

Abstract: A side body frame of a vehicle includes a collision load decentralization member coupled to an A pillar of a side outer panel, the A pillar being divided into a lower reinforcement part, an intermediate reinforcement part, and an upper reinforcement part, where the collision load decentralization member decentralizes a collision load transferred from a tire by a collision deformation to a door load decentralization flow path passing through the intermediate reinforcement part and a side sill load decentralization flow path passing through the lower reinforcement part.

Abstract: A side body frame of a vehicle includes a collision load decentralization member coupled to an A pillar of a side outer panel, the A pillar being divided into a lower reinforcement part, an intermediate reinforcement part, and an upper reinforcement part, where the collision load decentralization member decentralizes a collision load transferred from a tire by a collision deformation to a door load decentralization flow path passing through the intermediate reinforcement part and a side sill load decentralization flow path passing through the lower reinforcement part.

Abstract: The invention provides a semi-solid chewable dosage form for use as an over-the-counter medication that contains an active pharmaceutical ingredient to treat symptoms associated with allergies, colds, coughs, fever, pain, gastrointestinal disorders, sleep, and other common conditions. The invention further provides a semi-solid chewable dosage form that contains an active pharmaceutical ingredient, a gelling agent, gelatin, sugar, a polyol, and a pH adjusting agent. The invention also provides a semi-solid chewable dosage form that contains a gelling agent, sugar, a polyol, glycerin, and a pH adjusting agent.

Abstract: The invention provides a semi-solid chewable dosage form that contains one or more active pharmaceutical ingredients that are generally available as over-the-counter medications including, for example, chlorpheniramine maleate, phenylephrine hydrochloride, guaifenesin, dextromethorphan hydrobromide, loratadine, or a combination thereof. The invention further provides a semi-solid chewable dosage form that contains chlorpheniramine maleate, phenylephrine hydrochloride or a combination thereof, a gelling agent, gelatin, sugar, a polyol, and a pH adjusting agent. The invention further provides a semi-solid chewable dosage form that contains the active pharmaceutical ingredient chlorpheniramine maleate, phenylephrine hydrochloride or a combination thereof, a gelling agent, gelatin, sugar, corn syrup, and a pH adjusting agent. The semi-solid chewable dosage form is useful for administration to individuals to treat symptoms from allergies, colds, congestion, and the like.

Abstract: Methods for predicting patient deterioration or clinical events by detecting patterns in heterogeneous temporal clinical data streams that are predictive of certain clinical end points and matching the patient state with those patterns are described. The detected patterns, referred to as SuperAlarm triggers, are a predictive combination of frequently co-occurring monitor alarms, conditions and laboratory test results that can predict patient deterioration for imminent life-threatening events. SuperAlarm triggers may also exhibit patterns in the sequence of SuperAlarms that are triggered over the monitoring time of a patient. Sequential patterns of SuperAlarm triggers may also indicate a temporal process of change in patient status. SuperAlarm based alerts will also greatly reduce the number of false alarms and alarm fatigue compared to conventional alarms.

Abstract: The present invention discloses a method of spectrum utilization in a wireless cellular environment with coverage of at least two wireless networks and a related apparatus. The method includes: determining a RSRP threshold; detecting, by a small-cell base station, RSRPs of at least one large-cell base station; and comparing the highest one of the detected RSRPs with the determined RSRP threshold, adopting a separate spectrum mode if the highest one of the detected RSRPs exceeds the determined RSRP threshold, and otherwise, adopting a shared spectrum mode.

Abstract: The present invention provides vectors, including a novel attenuated strain of Salmonella, for efficient gene transfer into an animal, e.g. a mammalian host.

Abstract: The invention provides a semi-solid chewable dosage form for use as an over-the-counter medication that contains an active pharmaceutical ingredient to treat symptoms associated with allergies, colds, coughs, fever, pain, gastrointestinal disorders, sleep, and other common conditions. The invention further provides a semi-solid chewable dosage form that contains an active pharmaceutical ingredient, a gelling agent, gelatin, sugar, a polyol, and a pH adjusting agent. The invention also provides a semi-solid chewable dosage form that contains a gelling agent, sugar, a polyol, glycerin, and a pH adjusting agent.