Abstract: The present invention relates to (a) an active camptothecin derivative represented by Chemical Formula 1 below, which is designed to bind to the DDX5 protein and an E3 ligase; (b) a prodrug thereof designed to release the active camptothecin derivative (a) at an in vivo target site; or (c) a ligand-containing complex targeting the DDX5 protein, in which an topoisomerase-1 inhibitory ability of the active camptothecin derivative (a) or FL118 compound of Chemical Formula 2 is inactivated through linker conjugation. The active camptothecin derivative designed according to the present invention may bind to the DDX5 protein in cells to induce cell death through DDX5 protein degradation.

Abstract: An example system includes an implantable medical device and processing circuitry.

Abstract: A method and device for estimating a gaze distance of a user using hybrid scheme may accurately estimate a gaze distance of a user robustly against a difference in physiological characteristics of the user and a change in external environment using information of a binocular image and information of a depth image in a complementary manner by determining a final gaze distance of the user based on a first gaze distance of the user estimated based on a binocular convergence angle of the user and a second gaze distance of the user estimated based on a depth value of the gaze point of the user.

Abstract: Provided are a 3 level pulse amplitude modulation (PAM3) transmitter, an operating method of the PAM3 transmitter, and an electronic device including the same. The PAM3 transmitter includes a driver configured to convert input data into PAM3 signals, an eye monitor circuit electrically connected to an output terminal of the driver and configured to monitor upper eye patterns and lower eye patterns of the PAM3 signals, and a duty cycle adjust circuit configured to adjust a duty cycle of the input data provided to the driver.

Abstract: A scene flow estimation method includes: inputting a frame pair into an artificial intelligence (AI) network, and obtaining therefrom a motion embedding feature and a non-occluded-category label embedding feature corresponding to a target pixel in the frame pair; and estimating a scene flow corresponding to the frame pair based on the motion embedding feature and the non-occluded-category label embedding feature, the frame pair includes a first frame and a second frame, the first frame including a first color image and a first depth image and the second frame including a second color image and a second depth image, the non-occluded-category label embedding feature includes category information of an object corresponding to a pixel pair in the frame pair, the pixel pair includes a first pixel of the first frame and a second pixel of the second frame, and the second pixel corresponds to the first pixel.

Abstract: A composition for the surface treatment of a polymer material includes a hyperbranched polyglycerol comprising a glycidol-derived repeating unit and an unsubstituted or substituted acrylate group at least at one end thereof. The composition has the effect of suppressing fibrosis, thrombus formation, or inflammatory cell adsorption by preventing proteins from being adsorbed to the surface of a polymer material that is surface-treated with the composition or an in-vivo implantation material including a polymer material.

Abstract: A method of providing a specialized document sharing platform by a platform application executed by at least one processor of a terminal includes obtaining a first specialized document, generating question and answer content for the first specialized document using a question and answer language model, generating promotional content, which comprises an online promotional material for the first specialized document, based on the question and answer content, providing a promotional material production workspace based on the promotional content, determining promotional start content, which comprises the promotional content to be registered on the specialized document sharing platform, using the promotional material production workspace, and providing the promotional start content using the specialized document sharing platform.

Abstract: Disclosed herein is a washing machine that includes a tub disposed in a main body of the washing machine to store water. A circulation apparatus includes a circulation pump operable to circulate the water in and out of the tub. A detergent supply apparatus is coupled to the circulation apparatus to discharge detergent to the circulation apparatus so that operation of the circulation pump causes the discharged detergent to be supplied to the tub.

Abstract: The present application can provide a thin polarizing plate having excellent antireflection performance in all directions including the side as well as the front, and having excellent folding durability and durability against short wavelengths. In addition, the present application can provide an organic light-emitting display device to which the polarizing plate is applied and a display device comprising the same.

Abstract: An exemplary method and system is disclosed that facilitates the monitoring of worker's productivity and safety, for example, at a construction site and other like labor-intensive occupation and settings. The exemplary method and system provides wearable-based motion sensing and/or proximity sensing between worker and construction equipment. A study discussed herein suggests that sensing at two or more torso locations can provide 95% accuracy in classifying worker's action or motion at a construction site. In some embodiments, as discussed herein, the acquired sensed data are transmitted, over a mesh network, e.g., established between the wearable devices, to a cloud infrastructure to facilitate the real-time monitoring of action and actions that such sites.

Abstract: A polymer separator with improved charge and discharge performance and thermal stability, includes a porous polymer substrate and a coating layer formed on at least one surface of the porous polymer separator. The coating layer includes: functional group bonded to double bond-containing PVDF (DPVDE); and inorganic oxide particles bonded to the functional group.

Abstract: A sound absorption and isolation module is configured to reduce noise radiated from a tire and an operation apparatus thereof. The sound absorption and isolation module is formed by integrally combining a box outer plate, a sound isolation sheet, a sound absorption material, and a pad member. The sound absorption and isolation module is used to reduce the noise radiated from the tire and generated during a roll-and-brake process.

Abstract: An integrated circuit device may include a transmission driver and an equalizer. The transmission driver may be configured to, in response to a transmission control data, transmit an output signal to an outside through a signal line in a transmission operation that outputs the output signal to the outside, and provide termination resistance in a reception operation that receives an input signal from the outside through the signal line. The equalizer may be configured to, in response to an equalizer control data, amplify high-frequency components of the output signal in the transmission operation, and to provide termination resistance in the reception operation.

Abstract: The present disclosure relates to a hydrophilic modified polymer membrane and a method for fabricating the same, and more specifically, to a polymer membrane dip-coated with double bond-containing PVDF (DPVDF) and modified to be hydrophilic by reaction with a polymer or monomer containing an amine group, and a method of fabricating the same. The polymer membrane of the present disclosure is fabricated by physically coating a porous polymer substrate by dip coating with DPVDF, and then chemically modifying the surface of the dip-coated substrate to be hydrophilic using a polymer or monomer containing an amine group. That is, the polymer membrane is fabricated by performing both physical coating and chemical coating so that the dissolution of inorganic particles in the membrane can be further suppressed.

Abstract: Disclosed are semiconductor fabrication methods and optical proximity correction (OPC) methods. The semiconductor fabrication method comprises performing OPC on a design pattern of a layout to generate a corrected layout, and forming a photoresist pattern on a substrate by using a photomask manufactured with the corrected layout. Performing the OPC includes generating shape points on a contour of the design pattern, producing a hash value of the shape point, selecting a first unique shape point that represents first shape points, determining a first correction bias of the first unique shape point, and creating a correction pattern by applying the first correction bias in common to the first shape points. Producing the hash value includes generating a query range around a target shape point and, based on geometry analysis in the query range, producing the hash value.

Abstract: A method of fabricating a semiconductor device is disclosed. The method includes performing an optical proximity correction (OPC) on a design pattern of a layout and forming a photoresist pattern on a substrate using a photomask manufacture based the corrected layout. The performing of the OPC includes analyzing a cell hierarchy to choose a representative cell in the layout, dividing the design pattern in the representative cell into a plurality of segments including first segments, choosing a first unique segment, which represents the first segments, from the plurality of segments, generating a first correction bias of the first unique segment, applying the first correction bias to all of the first segments to generate a correction pattern, and applying a correction result of the representative cell to other cells that are included in the layout and are of a same type as the representative cell.

Abstract: Disclosed is an operating method of an electronic device for manufacture of a semiconductor device. The operating method includes receiving a layout image of the semiconductor device, generating an intermediate image by generating assist features based on main features of the layout image, evaluating a process result by performing simulation based on the intermediate image, and correcting the intermediate image by correcting shapes of the main features and/or the assist features of the intermediate image based on the process result.

Abstract: The present invention relates to a computer-implemented method for assessing and determining a complexity level of at least a portion, or pillar, of a clinical trial study. The method may be implemented by a computing device including at least a processor; a memory and an input and/or output elements. It comprises the steps of selecting and/or defining a clinical trial protocol and, based on the selection and/or definition thereof, activating and/or generating data entries for a set of corresponding parameters correlated to a set-up of the portion of the clinical trial study. The parameters refer to objectives; and/or design; and/or methods; and/or patient assessment procedures and/or patient data collection schedules of the clinical trial study.

Abstract: The present invention relates to a method for preparing a fuel cell catalyst electrode, which includes dispersing and mixing a first catalyst, a binder, and a first solvent to prepare a first catalyst slurry, heat-treating and pulverizing the first catalyst slurry to prepare a first catalyst powder, dispersing and mixing a second catalyst, a binder, and a second solvent to prepare a second catalyst slurry, heat-treating and pulverizing the second catalyst slurry to prepare a second catalyst powder, dispersing the first catalyst powder and the second catalyst powder in a third solvent to prepare a third catalyst slurry, and applying or transferring the third catalyst slurry onto a substrate to prepare an electrode having a catalyst layer formed therein.

Abstract: An air conditioner including: a housing having a discharge port and a plurality of holes; a door capable of closing the discharge port; a heat exchanger provided in the housing; a compressor connected to the heat exchanger so as to circulate a refrigerant so that same passes through the heat exchanger; a fan for blowing air so that the air passes through the heat exchanger and is discharged through the discharge port and at least one of the plurality of holes. The air conditioner includes a humidity sensor provided inside the housing so as to sense the humidity of the air having passed through the heat exchanger; and a control unit for controlling the door so as to open or close the discharge port and rotating the fan, on the basis of the humidity sensed by the humidity sensor when the compressor has been stopped.