Abstract: Methods, apparatus, systems, and articles of manufacture are disclosed to optimize projection of big data beyond its footprint. An example apparatus includes memory, instructions, and processor circuitry to access panel audience sizes corresponding to subscribers of a media provider, a subset of the subscribers of the media provider, and corresponding to a media network determine a relative percent difference between the third panel audience size and the fourth panel audience size, when the relative percent absolute difference satisfies a first threshold, determine percentages of demographic groups represented in the panel audience sizes, determine differences associated with the demographic groups, and when at least one of the differences corresponding to at least one of the demographic groups satisfies a second threshold, determine the subscribers, the subset of the subscribers, and the at least one of the demographic groups as useable to determine an audience size of the media network.