Abstract: A chamfered narrow side copper plate for a mold with a funnel-shaped curved surface has a working face contacting molten steel that includes a middle area and two chamfered areas, which are arranged at two sides. The working face has a funnel-shaped curved surface, which is larger at a top and smaller at a bottom. The chamfered narrow side copper plate for mold with funnel-shaped curved surface can ensure the uniformity of the cooling effect of the chamfered surface and enhance the service life of the narrow side copper plate.

Abstract: The invention relates to a cone-shaped crusher including a frame having a cavity, a main shaft disposed eccentrically in the frame, and an eccentric drive making the main shaft perform a gyratory movement. The eccentric drive includes an upper eccentric shaft, a lower eccentric shaft, and an eccentric bearing. The upper eccentric shaft has an opening provided at its central portion to allow the lower end portion of the main shaft to pass through the opening, and an upper coupling part provided at its lower portion and fastened to the lower eccentric shaft. The lower eccentric shaft has a lower coupling part fastened to the upper eccentric shaft. The eccentric bearing accommodates the lower end portion of the main shaft and is disposed in a space defined by the upper eccentric shaft and the lower eccentric shaft.

Abstract: A cone-shaped crusher according to the invention includes a frame having a cavity; a main shaft that is disposed in the cavity; main shaft driving means for driving the main shaft such that the main shaft performs a gyratory movement; a mantle core assembly body that performs a gyratory movement together with the main shaft; a suspension bearing chamber capable of accommodating an upper end portion of the main shaft; and a suspension bearing. According to the cone-shaped crusher, there are advantages in that damage to the suspension bearing can be minimized, the gyratory movement of the main shaft can be stably performed, and a suspension bearing part can be used semi-permanently without requiring replacement.

Abstract: An osmotic dosage form which comprising: (a) a core comprising a biologically active ingredient; (b) a semi-permeable membrane covering said core; and (c) at least one passageway through the semi-permeable membrane, wherein the semi-permeable membrane comprises ethyl cellulose, an acrylic or methacrylic polymer and a water-soluble plasticizer with the proviso that the semi-permeable membrane comprises no or not more than 15 weight percent of a water-soluble material excluding any water-soluble plasticizer, based on the total dry weight of the semi-permeable membrane.

Abstract: A paliperidone double-layered osmotic pump controlled release tablet and the preparation method thereof are disclosed. The double-layered osmotic pump controlled release tablet comprises a rigid membrane, a push layer, a drug layer, an isolation layer and an aesthetic coating, wherein the rigid membrane contains a semi-permeable polymer, a porogen and/or a plasticizer and has one or more drug release orifices on one end, the push layer comprises an expanding material, an osmotic agent, a binder, a colorant and a lubricant, the drug layer contains a pharmaceutically active ingredient, a hydrophilic polymer, an osmotic agent, a colorant, a lubricant and an antistatic agent, the isolation layer is located between the inner surface of the rigid membrane and the push layer, and contains a hydrophilic polymer. The paliperidone double-layered osmotic pump controlled release tablet shows an increasing drug release rate at early stage and keeps a constant drug release rate at later stage.

Abstract: A chamfered narrow side copper plate for a mould with a funnel-shaped curved surface has a working face contacting molten steel that includes a middle area and two chamfered areas, which are arranged at two sides. The working face has a funnel-shaped curved surface, which is larger at a top and smaller at a bottom. The chamfered narrow side copper plate for mould with funnel-shaped curved surface can ensure the uniformity of the cooling effect of the chamfered surface and enhance the service life of the narrow side copper plate.

Abstract: The invention relates to a cone-shaped crusher including a frame having a cavity, a main shaft disposed eccentrically in the frame, and an eccentric drive making the main shaft perform a gyratory movement. The eccentric drive includes an upper eccentric shaft, a lower eccentric shaft, and an eccentric bearing. The upper eccentric shaft has an opening provided at its central portion to allow the lower end portion of the main shaft to pass through the opening, and an upper coupling part provided at its lower portion and fastened to the lower eccentric shaft. The lower eccentric shaft has a lower coupling part fastened to the upper eccentric shaft. The eccentric bearing accommodates the lower end portion of the main shaft and is disposed in a space defined by the upper eccentric shaft and the lower eccentric shaft.

Abstract: A chamfered narrow side copper plate for a mold with a funnel-shaped curved surface has a working face contacting molten steel that includes a middle area and two chamfered areas, which are arranged at two sides. The working face has a funnel-shaped curved surface, which is larger at a top and smaller at a bottom. The chamfered narrow side copper plate for mold with funnel-shaped curved surface can ensure the uniformity of the cooling effect of the chamfered surface and enhance the service life of the narrow side copper plate.

Abstract: A cone-shaped crusher according to the invention includes a frame having a cavity; a main shaft that is disposed in the cavity; main shaft driving means for driving the main shaft such that the main shaft performs a gyratory movement; a mantle core assembly body that performs a gyratory movement together with the main shaft; a suspension bearing chamber capable of accommodating an upper end portion of the main shaft; and a suspension bearing. According to the cone-shaped crusher, there are advantages in that damage to the suspension bearing can be minimized, the gyratory movement of the main shaft can be stably performed, and a suspension bearing part can be used semi-permanently without requiring replacement.

Abstract: A paliperidone double-layered osmotic pump controlled release tablet and the preparation method thereof are disclosed. The double-layered osmotic pump controlled release tablet comprises a rigid membrane, a push layer, a drug layer, an isolation layer and an aesthetic coating, wherein the rigid membrane contains a semi-permeable polymer, a porogen and/or a plasticizer and has one or more drug release orifices on one end, the push layer comprises an expanding material, an osmotic agent, a binder, a colorant and a lubricant, the drug layer contains a pharmaceutically active ingredient, a hydrophilic polymer, an osmotic agent, a colorant, a lubricant and an antistatic agent, the isolation layer is located between the inner surface of the rigid membrane and the push layer, and contains a hydrophilic polymer. The paliperidone double-layered osmotic pump controlled release tablet shows an increasing drug release rate at early stage and keeps a constant drug release rate at later stage.

Abstract: This invention involves in metal solidification and continuous casting field, especially a chamfered narrow side copper plate for mould with funnel-shaped curved surface. The working face of the narrow side copper plate (1) contacting molten steel comprise a middle area (2) and two chamfered areas (3, 4) which are arranged at two sides, and said working face has a funnel-shaped curved surface which is big at top and small at bottom. In present invention, the chamfered narrow side copper plate for mould with funnel-shaped curved surface can ensure the uniformity of the cooling effect of the chamfered surface and enhance the service life of the narrow side copper plate.

Abstract: An osmotic dosage form which comprising: (a) a core comprising a biologically active ingredient; (b) a semi-permeable membrane covering said core; and (c) at least one passageway through the semi-permeable membrane, wherein the semi-permeable membrane comprises ethyl cellulose, an acrylic or methacrylic polymer and a water-soluble plasticizer with the proviso that the semi-permeable membrane comprises no or not more than 15 weight percent of a water-soluble material excluding any water-soluble plasticizer, based on the total dry weight of the semi-permeable membrane.

Abstract: A glipizide controlled release composition is provided comprising a drug-layer and a push-layer at a ratio of 1:0.5˜3 by weight. The drug-layer contains glipizide and 40˜99 percent by weight of the drug-layer of hydrophilic polyvinylpyrrolidone homopolymer and/or copolymer carrier. The push-layer comprises about 10 to 80 percent by weight of the push-layer of osmopolymers, about 10 to 80 percent by weight of the push-layer of water-insoluble polymers, and about 5 to 50 percent by weight of the push-layer of osmagents. The composition is used in osmotic pump tablets for controlled release of glipizide useful for administration once a day.

Abstract: A nifedipine controlled release composition is provided comprising a drug-layer and a push-layer at a ratio of 1:0.5˜3 by weight. The drug-layer contains nifedipine and 40˜99 percent by weight of the drug-layer of hydrophilic polyvinylpyrrolidone homopolymer and/or copolymer carrier. The push-layer comprises about 10 to 80 percent by weight of the push-layer of osmopolymers, about 10 to 80 percent by weight of the push-layer of water-insoluble polymers, and about 5 to 50 percent by weight of the push-layer of osmagents. The composition is used in osmotic pump tablets for controlled release of nifedipine useful for administration once a day.

Abstract: A drug core composition is described for enhancing controlled delivery of pharmaceutical active agents with low solubility in water. The drug core composition contains at least a drug-layer and a push-layer. The drug-layer contains at least a pharmaceutical active agent with low solubility in water and a hydrophilic polymer carrier. The push-layer contains at least osmopolymers, water-insoluble polymers and osmagents. An osmotic pump system containing the drug core composition is described wherein a semi-permeable membrane is coated outside of the drug core composition. The drug core composition provides drug release at a controlled rate particularly adaptable for release of therapeutic dosages over a period of 24 hours when administered once a day.

Abstract: An osmotic pump device for delivery of tamsulosin or a pharmaceutically acceptable salt thereof to the gastrointestinal tract is provided. The device is a two-layer device comprising a drug containing layer containing as a carrier about 10 to 99 percent by weight of the first layer a polyvinylpyrrolidone polymer and/or copolymer, and a second layer comprising about 10 to 80 percent by weight of the second layer of water-insoluble volume-swellable polymers, about 80 to 10 percent by weight of the second layer of osmopolymers, and about 5 to 50 percent by weight of the second layer of osmagents.

Abstract: The present invention relates to a vertical shaft impact crusher, and more specifically, to a vertical shaft impact crusher designed to be able to efficiently crush objects to be crushed and maximize the lifespan of a rotor.