Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.

Abstract: A fully-automated terminal crimping device for facilitating cable positioning includes an upper pressing die crimping mechanism, cable positioning mechanisms, an ejection mechanism, a terminal pushing slider mechanism, and a terminal clamping mechanism, where the terminal pushing slider mechanism is arranged directly below the upper pressing die crimping mechanism, a lower pressing die base is arranged on the terminal pushing slider mechanism, the terminal clamping mechanism and the ejection mechanism are arranged at the left and right sides of the lower pressing die base respectively, and the two cable positioning mechanisms are arranged at the front and rear ends of the lower pressing die base respectively.

Abstract: The present disclosure relates to a vibrating mirror adjustment apparatus, system and method, and a projector. The vibrating mirror adjustment apparatus includes: an image feature acquiring module, an image identifying module, a resolution extracting module, and a vibrating mirror control module. The vibrating mirror adjustment apparatus identifies the category of the projected image and the resolution information corresponding to the projected image based on the acquired information feature of the projected image, then identifies whether vibration of the vibrating mirror is used to improve a resolution of an image, and further automatically controls the on or off state of the vibrating mirror, such that an optimal projection display effect is achieved, and visual enjoyment of a user is greatly improved.

Abstract: The present application provides a preparation method for a core-shell structured tungsten/gadolinium oxide functional fiber for X and ? ray protection, comprising: first preparing a core-shell structured tungsten/gadolinium oxide powder; preparing a W@Gd2O3/PP blended melt from the powder; and preparing a W@Gd2O3/PP composite fiber from the blended melt. The core-shell structured tungsten/gadolinium oxide functional fiber prepared by the method can play a role in synergistic protection in the aspect of radiation protection, eliminate a weak protection area, and effectively absorb secondary radiation generated by radiation. Secondly, the prepared functional fiber has the characteristics of no lead and light weight, and has good application prospects in the aspect of X and ? ray radiation protection.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may receive a synchronization signal block (SSB) comprising a plurality of symbols. The UE may obtain, during a plurality of measurement windows, a plurality of measurements associated with a beam group of a plurality of reception beams corresponding to a plurality of symbols of the SSB, wherein the beam group is associated with a serving cell and comprises a first set of beams and a second set of beams, wherein each beam of the beam group corresponds to a measurement window having a window size that is less than a size of a corresponding symbol of the plurality of symbols of the SSB. The UE may perform a wireless communication task based on the plurality of measurements. Numerous other aspects are described.

Abstract: This application describes a model training method, applied to the field of artificial intelligence. The method includes a computing core of a first processor obtains an embedding used for model training, and writes an updated embedding to a first memory of the first processor instead of transferring the updated embedding to a second processor after model training is completed. In this application, after updating an embedding, the first processor saves the updated embedding to the first memory of the first processor. Without needing to wait for the second processor to complete a process of transferring a second target embedding to a GPU, the first processor may directly obtain the updated embedding and perform model training of a next round based on the updated embedding, provided that the first processor may obtain a latest updated embedding.

Abstract: The present disclosure provides a deuterium-modified thienopyridone compound, a preparation method therefor, a pharmaceutical composition thereof, and a medical use thereof. The deuterium-modified thienopyridone compound is shown in formula I, and has been shown to inhibit HPK1 kinase activity, being capable of achieving an anti-tumour effect.

Abstract: A method for manufacturing a transparent heat-insulation building material from waste wood is provided. The method includes the following steps of: step S1, wood pretreatment, drying immersing, heating, adding a complexing agent solution, stirring, then drying the wood; step S2, wood acetylation treatment, loading the wood into a pressure vessel, adding acetylation fluid, reducing the pressure, and then pressurizing and raising a temperature; step S3, resin impregnating, adding a methyl methacrylate monomer solution and heating it, adding the methyl methacrylate monomer and benzoyl peroxide, bleaching the wood by hydrogen peroxide, and placing them in a vacuum permeator to allow the prepolymer liquid to penetrate into the wood and collecting the prepolymer liquid; and step S4, hot press molding polymerizing the wood in an oven and sleeving it into a heat press molding to obtain a densified wood.

Abstract: Provided is an antibody drug conjugate, specifically comprising a therapeutic antibody moiety, an intermediate linker moiety and a cytotoxic drug moiety which are linked. The therapeutic antibody moiety is an antibody against an HER2 target. The cytotoxic drug moiety is a camptothecin topoisomerase I inhibitor. The cytotoxic drug moiety or the linker-cytotoxic drug moiety is modified by means of deuterium substitution. The antibody drug conjugate can be used for the prevention or treatment of cancers.

Abstract: The present application relates to the technical field of composite film, and more particularly, to a diaphragm composite material and a preparation method thereof. The diaphragm composite material includes a polyethylene naphthalate (PEN) film layer, an aluminum-plated film layer, an aerogel layer, and an elastic adhesive layer disposed between the PEN film layer and the aluminum-plated film layer for bonding the PEN film layer and the aluminum-plated film layer, the aerogel layer is coated on one side of the aluminum-plated film layer away from the elastic adhesive layer. The diaphragm composite layer of the present application has high strength and strong rigidity, has better vibration dampening and noise-reducing effects, and wear-resistant and corrosion-resistant effects, and is worthy of popularization.

Abstract: Provided is a compound as an Akt kinase inhibitor. The present invention specifically relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, a preparation method therefor, a pharmaceutical composition containing the compound, and the use thereof in the preparation of a drug for treating Akt kinase-related diseases.

Abstract: A fuel-cell hydrogen recycling system, comprising a fuel cell; a controller; a hydrogen recycling pipeline provided with a hydrogen circulating pump and a check valve; an air inlet pipeline and an air outlet pipeline connected to the fuel cell, respectively; a hydrogen inlet pipeline provided with a hydrogen inlet valve; and a hydrogen outlet pipeline provided with a hydrogen outlet valve, with the hydrogen recycling pipeline connected to the hydrogen inlet pipeline, wherein the system further comprises a gas-liquid separating reservoir, which comprises a reservoir positioned at its upper portion and a gas-liquid separator positioned at its lower portion communicated with each other vertically, the reservoir is connected to the hydrogen outlet pipeline and the hydrogen recycling pipeline, respectively, and the gas-liquid separator discharges exhaust water and redundant nitrogen through a exhaust pipeline that is provided with a ventilation valve.

Abstract: An aromatherapy nebulizer and an aroma diffuser of the same are proposed in the present invention. The aroma diffuser includes the aromatherapy nebulizer and a main body to mount the aromatherapy nebulizer. The aromatherapy nebulizer includes an atomizer; and an essential oil container. The atomizer includes an atomizing seat defined an atomization chamber therein and an outer cover defining a mist outlet. The atomizing seat is provided with an air conduit and a liquid conduit; the liquid conduit defines an essential oil channel therethrough. The essential oil channel is bent at one end of the liquid conduit which forms a liquid outlet, thereby the essential oil is absorbed upwards to the liquid conduct from the essential oil container and changes a direction sprayed out from the liquid outlet.

Abstract: An aromatherapy nebulizer and an aroma diffuser of the same are proposed in the present invention. The aroma diffuser includes the aromatherapy nebulizer and a main body to mount the aromatherapy nebulizer. The aromatherapy nebulizer includes an atomizer; and an essential oil container. The atomizer includes an atomizing seat defined an atomization chamber therein and an outer cover defining a mist outlet. The atomizing seat is provided with an air conduit and a liquid conduit; the liquid conduit defines an essential oil channel therethrough. The essential oil channel is bent at one end of the liquid conduit which forms a liquid outlet, thereby the essential oil is absorbed upwards to the liquid conduct from the essential oil container and changes a direction sprayed out from the liquid outlet.

Abstract: The present disclosure relates to an interactive projection input and output device, which includes: a projecting module, configured to display a screen mirroring content from an external device in a projection region of a projection picture corresponding to the external device; a coordinated operation capturing module, configured to: determine a first coordinate of a user coordinated operation point corresponding to a user coordinated operation behavior in a first coordinate system; a coordinated instruction generating module, configured to, generate a position information instruction according to the first coordinate of the user coordinated operation point and regional position information of the projection region in the first coordinate system; and a wireless transmission module, configured to receive screen mirroring information from the external device, and send the position information instruction to the external device, so as to operate the external device.

Abstract: Provided in this patent disclosure are two types of novel fluoro-monomers that can be polymerized for the fabrication of ion-exchange fluoropolymers. In addition, new proton-conductive zirconium-perfluorophosphonic acid fluoropolymer membranes that can reduce metal crossovers in redox flow batteries are also provided.

Abstract: The present application relates to the technical field of composite film, and more particularly, to a diaphragm composite material and a preparation method thereof. The diaphragm composite material includes a polyethylene naphthalate (PEN) film layer, an aluminum-plated film layer, an aerogel layer, and an elastic adhesive layer disposed between the PEN film layer and the aluminum-plated film layer for bonding the PEN film layer and the aluminum-plated film layer, the aerogel layer is coated on one side of the aluminum-plated film layer away from the elastic adhesive layer. The diaphragm composite layer of the present application has high strength and strong rigidity, has better vibration dampening and noise-reducing effects, and wear-resistant and corrosion-resistant effects, and is worthy of popularization.

Abstract: A delivery sheath includes an outer tubular layer and an initially folded inner tubular layer. When an implant passes therethrough, the outer tubular layer expands and the inner tubular layer unfolds into an expanded lumen diameter. The sheath may also include selectively placed longitudinal support rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion, thereby reducing the push force needed to advance the implant through the sheath's lumen.

Abstract: A method for allocating virtual reward resources performed by an electronic device are provided. The method includes: obtaining behavior information of each virtual character in a target camp during a teamfight of a game, the target camp including at least one virtual character, the behavior information being a behavior applied by each virtual character in the target camp to a virtual object, and the virtual object being a virtual character in at least one of the target camp or an enemy camp; determining, according to the behavior information, contribution information achieved by each virtual character in the target camp during the teamfight; determining, according to the contribution information, a target virtual character and a target virtual reward resource corresponding to the target virtual character from at least one virtual character included in the target camp; and updating attribute information of the target virtual character according to the target virtual reward resource.