Abstract: The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts and esters thereof: pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.

Abstract: Apparatus and methods for implementing a real-time Versatile Video Coding (VVC) decoder use multiple threads to address the limitation with existing parallelization techniques and fully utilizes the available CPU computation resource without compromising on the coding efficiency. The proposed Multi-threaded (MT) framework uses CTU level parallel processing techniques without compromising on the memory bandwidth. Picture level parallel processing separates the sequence into temporal levels by considering the picture's referencing hierarchy. Embodiments are provided using various optimization techniques to achieve real-time VVC decoding on heterogenous platforms with multi-core CPUs, for those bitstreams generated using a VVC reference encoder with a default configuration.

Abstract: A video decoder may be configured to output layers of video data according to layers specified in an output layer set mode as well as based on the actual layers received in an access unit. Accordingly, the video coder may be configured to output layers actually received rather than restart a video bitstream in situations where the layers actually received do not match the layers specified in the output layer set mode. In another example, a video encoder may disable inter prediction when the sub-picture ID of a sub-picture in a currently coded picture does not match the sub-picture ID of a sub-picture in a reference picture.

Abstract: A streaming device may request and download multi-layer video segments based on a number of factors including the artistic interest associated with the video segments and/or the status of a buffer area managed by the streaming device. The multi-layer segments may be coded using scalable coding techniques or a combination of scalable coding and simulcast coding techniques by which each of the video segments may be coded into one or more representations of different qualities and/or bitrates. When requesting the multi-layer segments, the streaming device may ensure that the fullness of the buffer area falls between a buffer underflow threshold and a backfilling threshold under various network conditions. The streaming device may estimate the available network bandwidth in order to facilitate the scheduling decisions. The streaming device may consider the artistic interest associated with the video segments during scheduling and may give priority to those segments with higher artistic interest.

Abstract: Embodiments contemplate coding video data by generating a video encoded bitstream that may include reference picture set (RPS) extensions for inter-layer reference pictures, and the extensions may include inter-layer delta Picture Order Counts (POCs). Embodiments may also include signaling that lower layer reference pictures may be available in a lower layer decoder picture buffer (DPB), and/or an aggregate DPB, that may be added to the RPS set of a higher layer. The bitstream may include a signal indicating whether the higher layer RPS may be specified by a lower layer RPS, and the lower layer RPS may be temporal, inter-layer prediction (ILP), or both.

Abstract: Methods and systems are disclosed for a mobile device to decode video based on available power and/or energy. For example, the mobile device may receive a media description file (MDF) from for a video stream from a video server. The MDF may include complexity information associated with a plurality of video segments. The complexity information may be related to the amount of processing power to be utilized for decoding the segment at the mobile device. The mobile device may determine at least one power metric for the mobile device. The mobile device may determine a first complexity level to be requested for a first video segment based on the complexity information from the MDF and the power metric. The mobile device may dynamically alter the decoding process to save energy based on the detected power/energy level.

Abstract: An automatic feeding device and method for a seedling bed of a transplanter, comprising: a bracket installed on the transplanter; several trays, obliquely arranged on the bracket downwards, and the bottom of the trays being provided with release mechanisms for releasing the rice seedling bed; a conveyor belt, arranged on the bracket; a photoelectric sensor, arranged on the transplanting platform; and a controller, in communication connection with the photoelectric sensor, when the photoelectric sensor detects that the height of the remaining rice seedling bed on the transplanting platform is lower than the height of the photoelectric sensor. Only one driver is needed to operate, so that the labor input is greatly reduced, and the labor intensity is reduced; meanwhile, the space is saved by the reduction of the number of workers, enabling more seedling raw materials to be stored.

Abstract: Described herein are systems, methods, and instrumentalities associated with video coding. The signaling of certain syntax elements may be moved from a slice header to a picture header and/or a layer access unit delimiter (AUD). The dependency between AUD and one or more parameter sets may be explored. Syntax elements may be signaled to enable wrap-around motion compensation for certain sub-picture(s) and specify wrap-around motion compensation offsets for the sub-picture(s).

Abstract: The present disclosure provides a ratiometric fluorescent probe, a preparation method thereof, and an application in detection of hydrogen peroxide. In the present disclosure, MoOx QDs (nanoenzymes) and Co/Zn-MOFs both have catalytic activity, and the large specific surface area and porous structure of Co/Zn-MOFs can provide more binding sites for the contact between nanoenzymes and substrates. Moreover, Co/Zn-MOFs have high catalytic activity similar to natural enzymes. When nanoenzymes with fluorescent properties encounter Co/Zn-MOFs with similar catalytic activity, they will collide with a spark of “synergy catalysis”, and the fusion of the two plays a role of synergy catalysis; in addition, the uniform cavity of Co/Zn-MOFs can provide “hosts” for nanoenzymes, and Co/Zn-MOFs provide “anchors” for MoOx QDs, avoiding the aggregation of MoOx QDs and enhancing the stability of the probe.

Abstract: A sensor system for measuring an angle of a gate of an isolating switch of overhead lines, comprising an optical fiber angle sensor, a base, a support plate, a light source fiber, a laser transmitter, an aluminum box, a relay, a step-down power module, a control circuit board, a photoelectric converter, and a receiving optical fiber. The support plate is arranged on an upper part of a pillar insulator; the optical fiber angle sensor is arranged on the base to detect a rotation angle of the gate; the laser transmitter is controlled to emit a laser beam into the light source fiber; the laser beam is received by the receiving optical fiber and transmitted to the photoelectric converter to convert a light intensity into a voltage signal; the converted voltage signal is transmitted to the control circuit board for processing, and the angle of the gate is output.

Abstract: A sensor system for measuring an angle of a gate of an isolating switch of overhead lines, comprising an optical fiber angle sensor, a base, a support plate, a light source fiber, a laser transmitter, an aluminum box, a relay, a step-down power module, a control circuit board, a photoelectric converter, and a receiving optical fiber. The support plate is arranged on an upper part of a pillar insulator; the optical fiber angle sensor is arranged on the base to detect a rotation angle of the gate; the laser transmitter is controlled to emit a laser beam into the light source fiber; the laser beam is received by the receiving optical fiber and transmitted to the photoelectric converter to convert a light intensity into a voltage signal; the converted voltage signal is transmitted to the control circuit board for processing, and the angle of the gate is output.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, ester, stereoisomer, tautomer, solvate, hydrate, or combination thereof: which inhibit the Apoptosis signal-regulating kinase 1 (ASK-1), which associated with autoimmune disorders, neurodegenerative disorders, inflammatory diseases, chronic kidney disease, cardiovascular disease. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from ASK-1 related disease. The invention also relates to methods of treating an ASK-1 related disease in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention specifically relates to methods of treating ASK-1 associated with hepatic steatosis, including non-alcoholic fatty liver disease (NAFLD) and non-alcohol steatohepatitis disease (NASH).

Abstract: Improved method and apparatus for signaling of reference pictures used for temporal prediction. The signaling schemes and construction process for different reference picture lists in HEVC Working Draft 5 (WD5) are improved.

Abstract: A streaming device may request and download multi-layer video segments based on a number of factors including the artistic interest associated with the video segments and/or the status of a buffer area managed by the streaming device. The multi-layer segments may be coded using scalable coding techniques or a combination of scalable coding and simulcast coding techniques by which each of the video segments may be coded into one or more representations of different qualities and/or bitrates. When requesting the multi-layer segments, the streaming device may ensure that the fullness of the buffer area falls between a buffer underflow threshold and a backfilling threshold under various network conditions. The streaming device may estimate the available network bandwidth in order to facilitate the scheduling decisions. The streaming device may consider the artistic interest associated with the video segments during scheduling and may give priority to those segments with higher artistic interest.

Abstract: Cross plane filtering may be used for enhanced chroma coding. An indication of a cross-plane filter associated with a current picture may be received. The current picture may include an intra-coded video block and a plurality of reference samples. The plurality of reference samples may be used to predict the intra-coded video block. A luma sample region may be determined in the current picture. The luma sample region may determined to enhance a corresponding chroma sample in the current picture. The cross-plane filter may be applied to a plurality of luma samples in the luma sample region to determine an offset. The cross-plane filter may be a high pass filter. The offset may be applied to the corresponding chroma sample to determine an enhanced chroma sample.

Abstract: Systems, methods, and instrumentalities are disclosed that relate to the processing of a media container file associated with 3D video data. The media container file may indicate that certain video-based point cloud compression (V-PCC) component tracks may be played together as a playout group. These V-PCG component tracks may represent respective encoded versions of one or more V-PCC components, and a video decoding device may play the tracks together in response to determining that the tracks belong to the same playout track group. The video decoding device may also determine from the media container file that certain PCC component tracks include tile groups that correspond to different objects in a point cloud or different parts of a same object in the point cloud. The video decoding device may decode these tile groups independently from each other so that a subset of the objects or parts of the point cloud may be accessed without also accessing the rest of the objects or parts.

Abstract: The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts and esters thereof: which inhibit the Apoptosis signal-regulating kinase 1 (ASK-1), which associated with autoimmune disorders, neurodegenerative disorders, inflammatory diseases, chronic kidney disease, cardiovascular disease. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from ASK-1 related disease. The invention also relates to methods of treating an ASK-1 related disease in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention specifically relates to methods of treating ASK-1 associated with hepatic steatosis, including non-alcoholic fatty liver disease (NAFLD) and non-alcohol steatohepatitis disease (NASH).

Abstract: Video encoders and video decoders are configured to supplemental enhancement information (SEI) messages. The SEI messages may include picture orientation transform type syntax elements that indicate how a picture may be rotated and/or mirrored. The SEI messages may also include quality metrics.

Abstract: Video encoders and video decoders are configured to supplemental enhancement information (SEI) messages. The SEI messages may include picture orientation transform type syntax elements that indicate how a picture may be rotated and/or mirrored. The SEI messages may also include quality metrics.

Abstract: A method applied to a terminal device includes displaying a first home screen, detecting a preset first input, opening, in response to the first input, a first application, displaying a screen of the first application, where the first input is an input of a user for opening the first application, detecting a preset second input, displaying a second home screen in response to the second input, where the second home screen is a home screen on which an icon of the first application is located, where the preset second input is an input of the user for exiting the screen of the first application, and the first home screen is different from the second home screen.