Abstract: The semiconductor memory device including a bit line in a first direction on a substrate, a channel structure on the bit line, and including a first vertical part in a second direction, and a second vertical part apart from the first vertical part in the first direction and in the second direction, a back-gate electrode on the bit line on a side of the channel structure and in the second direction, a back-gate insulating film between the back-gate electrode and the channel structure, a back-gate capping film on the back-gate electrode and the back-gate insulating film, a first and second word lines between the first and the second vertical parts and in the second direction, the second word line spaced apart from the first word line in the first direction and first and second capacitors connected to the first and second vertical parts, on the first and second vertical parts.

Abstract: A chemical supplier is proposed. The chemical supplier includes a bottle storing a fluid to be supplied therein and including a discharge port formed at a lower portion thereof, a reservoir including an inlet formed at an upper portion thereof, the inlet being fluidically connected to the discharge port, to receive the fluid to be supplied, which including an outlet formed at one portion thereof to supply the fluid to be supplied outward, a joint assembly of a mutual cognition structure, which is provided between the bottle and the reservoir to control physical coupling between the bottle and the reservoir, and a guide casing storing the bottle in a removable manner and supporting the bottle and the reservoir connected to each other by the joint assembly in a connected state. The chemical supplier has convenience of chemical replacement work, and can prevent errors in mounting and replacing a chemical.

Abstract: The present invention relates to: a recombinant protein in which an interferon-beta mutein, in which an amino acid residue is substituted, and an antibody binding to a specific antigen are fused together; and a pharmaceutical composition for treating cancer, the composition comprising, as active ingredients, a polynucleotide, an expression vector and a recombinant microorganism, and the recombinant protein. In the recombinant protein, the physical properties of interferon-beta are improved through site-specific mutation, and thus the recombinant protein may have improved biological activity and purification efficiency, and the productivity thereof can be increased.

Abstract: The present invention relates to an RNA in-vitro transcript mRNA for intracellular expression of a gene of interest and a pharmaceutical composition comprising same for vaccines. When injected into animal cells, the in-vitro transcript mRNA including the gene of interest according to the present invention allows the protein of interest to be expressed in the animal cell in large quantities, and, as such, can be used as a gene vaccine against autoimmune diseases, infectious diseases, cancer- or tumor-related diseases, inflammatory diseases, and so on.

Abstract: The present invention relates to a device and a method for measuring skin changes caused by blue light. A device for measuring skin changes caused by blue light according to one embodiment of the present invention comprises: at least one light source for irradiating light of a blue light band at different light amounts to a plurality of test areas set on a skin area to be tested; and a control unit for detecting a minimum pigmentation point among the test areas and calculating a light amount of the corresponding test area as a minimum pigmentation dose (MPD) for blue light. In addition, the present invention relates to a blue light irradiation device for irradiating a plurality of blue light beams in order to measure skin changes caused by blue light.

Abstract: The present invention relates to a pharmaceutical composition for diagnosing and treating prostate cancer, capable of targeting PSMA, and a compound provided by one aspect of the present invention has a glutamine-urea-lysine compound to which a radioactive metal-coupled chelator is structurally coupled and to which an aryl group that can additionally bind to PSMA protein is coupled. Coupling between the glutamine-urea-lysine compound and the chelator includes a polar spacer so as to serve the role of reducing in vivo nonspecific coupling and exhibit an effect of being rapidly removed from vital organs, but not from prostate cancer. These characteristics lower the radiation exposure, which is caused by a therapeutic radioisotope-coupled compound, to normal tissue and organs, and thus reduce side effects. In addition, a compound that contains a phenyl group having a coupling force with albumin has an increased residence time in the blood, thereby becoming more accumulated in prostate cancer.

Abstract: Disclosure provides a two-segment electromagnet stirring member, and a two-segment electromagnet semi-solid die-casting apparatus including the same, and a die-casting method using the same. The two-segment electromagnet stirring member includes a plurality of magnetic field generation parts therein, and includes a first electromagnetic stirring part and a second electromagnetic stirring part separated from each other. The first electromagnetic stirring part and the second electromagnetic stirring part are coupled to each other in a ring shape to surround an outer circumferential surface of a sleeve to perform electromagnetic stirring to molten metal in the sleeve, and are coupled to each other so as to position the plurality of magnetic field generation parts at radially equal gaps around the sleeve.

Abstract: Disclosed herein is an electrical connector including a plug connector mounted on a substrate and connected to a receptacle connector. The plug connector includes: a plug housing including a base and first to fourth walls; and multiple plug signal terminals disposed at least on the first wall. A recess is formed between the plug signal terminals to be located below an upper end of the first wall of the plug housing. In the receptacle connector as a mating connector, a protrusion is formed between receptacle signal terminals 20-3 to be located above a base of a receptacle housing of the receptacle connector. The recess of the plug connector (10) receives the protrusion of the receptacle connector therein.

Abstract: Disclosure provides a two-segment electromagnet stirring member, and a two-segment electromagnet semi-solid die-casting apparatus including the same, and a die-casting method using the same. The two-segment electromagnet stirring member includes a plurality of magnetic field generation parts therein, and includes a first electromagnetic stirring part and a second electromagnetic stirring part separated from each other. The first electromagnetic stirring part and the second electromagnetic stirring part are coupled to each other in a ring shape to surround an outer circumferential surface of a sleeve to perform electromagnetic stirring to molten metal in the sleeve, and are coupled to each other so as to position the plurality of magnetic field generation parts at radially equal gaps around the sleeve.

Abstract: Proposed is an electromagnetic vibration stirring device of semi-solid high pressure casting equipment. The electromagnetic vibration stirring device includes: a ring-shaped casing including an inner wall into which a sleeve is inserted and an outer wall spaced apart from the inner wall; and a magnetic field generating unit located between the inner wall and the outer wall of the casing, and including a plurality of electromagnets radially arranged at equal intervals around the sleeve in a circumferential direction of the sleeve, each of the electromagnets including a core and a coil surrounding the core. The magnetic field generating unit generates a magnetic field by applying a current to the electromagnets in a clockwise or counterclockwise direction, and each portion of a semi-solid molten metal is sequentially vibrated by the magnetic field along the circumferential direction of the sleeve, thereby controlling a microstructure of the molten metal.

Abstract: Various embodiments provide an electronic device and a method, the device comprising: a capacitive sensor, a heart rate sensor including at least one light-emitting unit, a first light receiving unit, and a second light receiving unit; and a processor, wherein the processor is configured to: measure capacitance for a user wearing the electronic device by using the capacitive sensor; emit light by using the light-emitting unit according to the capacitance; measure a first amount of light which is said light reflected by the user's body tissue through the first light receiving unit, and a second amount of light which is said light reflected by the body tissue through the second light receiving unit; determine that the electronic device is worn by the user when at least one amount of light of the first amount of light and the second amount of light satisfies an amount of light in a specified range; and determine that the electronic device is detached from the user when the first amount of light and the second am

Abstract: Disclosed is a transfer learning system for a deep neural network. The transfer learning system includes a pre-trained model storage unit configured to store a plurality of pre-trained models that are deep neural network models learned using one or more pre-training datasets, a transfer learning data input unit configured to receive transfer learning data, a pre-trained model selecting unit configured to select a pre-trained model corresponding to the transfer learning data from among the plurality of stored pre-trained models, and a transfer learning unit configured to generate one or more transfer learning models by performing transfer learning using the selected pre-trained model and the transfer learning data.

Abstract: The present invention relates to: a biomarker composition for predicting the prognosis of brain disease caused by microplastic exposure; and a use thereof. More particularly, it was confirmed that polyethylene microspheres (PS) in a mouse animal model orally administered with the PS penetrate brain tissue to change the level of metabolites inside the brain tissue and the diversity of intestinal microorganisms, thereby causing brain disease, and thus the present invention is intended to provide a biomarker composition for predicting the prognosis of brain disease caused by microplastic exposure, and a method for predicting the prognosis of brain disease using same.

Abstract: Proposed is an electromagnetic vibration stirring device of semi-solid high pressure casting equipment. The electromagnetic vibration stirring device includes: a ring-shaped casing including an inner wall into which a sleeve is inserted and an outer wall spaced apart from the inner wall; and a magnetic field generating unit located between the inner wall and the outer wall of the casing, and including a plurality of electromagnets radially arranged at equal intervals around the sleeve in a circumferential direction of the sleeve, each of the electromagnets including a core and a coil surrounding the core. The magnetic field generating unit generates a magnetic field by applying a current to the electromagnets in a clockwise or counterclockwise direction, and each portion of a semi-solid molten metal is sequentially vibrated by the magnetic field along the circumferential direction of the sleeve, thereby controlling a microstructure of the molten metal.

Abstract: The present invention relates to a human interferon-beta variant with double mutation and a method for improving stability of a human interferon-beta variant and, more specifically, to a human interferon-beta variant including an amino acid sequence having serine substituted for the 17th amino acid cysteine of human interferon-beta and threonine substituted for the 27th amino acid arginine of the human interferon-beta, and a method for improving stability of human interferon-beta R27T variant, the method comprising a step of substituting serine for the 17th amino acid serine in the human interferon-beta R27T variant in which threonine is substituted for the 27th amino acid arginine of human interferon-beta.

Abstract: A battery module for a vehicle includes a cell module in which battery cells are overlapped with each other while having a predetermined directivity, and a cooling channel module directly bonded to at least one surface parallel to an overlap direction of the battery cells of the cell module, the cooling channel module having a refrigerant circulated therein, where a cell bonding surface of the cooling channel module has a wave-shaped cross section curved along a curvature formed by end portions of the overlapped battery cells.

Abstract: The present invention relates to a method for structure learning and model compression for a deep neural network. The method for structure learning and model compression for a deep neural network according to an embodiment of the present invention includes (a) generating a parameter for a neural network model, (b) generating an objective function corresponding to the neural network model on the basis of the parameter, and (c) performing training on the parameter and performing model learning on the basis of the objective function and learning data.

Abstract: The present invention relates to a transgenic cloned pig for xenotransplantation in which porcine endogenous retrovirus (RUN) EnvC is negative, ?1,3-galactosyltransferase (GGTA1), CMP-N-acetylneuraminic acid hydroxylase (CMAH), isoglobotrihexosylceramide synthase (iGb3s), and beta-I,4-N-acetyl-galactosaminyl transferase2 (?4GalNT2) are knocked out, and human CD46 and thrombomodulin (TBM) genes are expressed, and to a method of preparing the transgenic cloned pig. The transgenic cloned pig according to the present invention may overcome hyperacute and antigen-antibody mediated immune rejection reaction, immune rejection reaction due to blood coagulation, and immune rejection reaction due to complement activity, without causing transfer of porcine endogenous retrovirus that occurs in xenotransplantation. Therefore, the transgenic cloned pig according to the present invention may be usefully utilized as a donor animal for xenotransplantation of organs and cells.

Abstract: Proposed is an electromagnetic vibration stirring device of semi-solid high pressure casting equipment. The electromagnetic vibration stirring device includes: a ring-shaped casing including an inner wall into which a sleeve is inserted and an outer wall spaced apart from the inner wall; and a magnetic field generating unit located between the inner wall and the outer wall of the casing, and including a plurality of electromagnets radially arranged at equal intervals around the sleeve in a circumferential direction of the sleeve, each of the electromagnets including a core and a coil surrounding the core. The magnetic field generating unit generates a magnetic field by applying a current to the electromagnets in a clockwise or counterclockwise direction, and each portion of a semi-solid molten metal is sequentially vibrated by the magnetic field along the circumferential direction of the sleeve, thereby controlling a microstructure of the molten metal.

Abstract: Various embodiments of the present invention relate to: an electronic device capable of measuring illuminance by using an optical sensor and providing information on the measured illuminance to a user; and an operating method therefor.