Patents by Inventor Yong-Jun Liu

Yong-Jun Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7271248
    Abstract: Nucleic acids encoding mammalian Toll-like receptors (TLRs) have been identified in human cells. Recombinantly produced TLRs are used in the preparation of antibodies that are capable of binding to the TLRs. The antibodies are advantageously used in the prevention and treatment of septic shock, inflammatory conditions, and viral infections.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: September 18, 2007
    Assignee: Schering Corporation
    Inventors: Gerard T. Hardiman, Fernando L. Rock, J. Fernando Bazan, Robert A. Kastelein, Stephen W. K. Ho, Yong-Jun Liu
  • Publication number: 20070178093
    Abstract: Provided are methods of modulating activity of regulatory T cells, CD4+ T cells, and CD8+ T cells. Also provided are methods of treating immune disorders.
    Type: Application
    Filed: February 15, 2007
    Publication date: August 2, 2007
    Applicant: Schering Corporation
    Inventors: Shino Hanabuchi, Rene de Waal Malefyt, Yong-Jun Liu
  • Publication number: 20070048781
    Abstract: Purified genes encoding cytokines from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Application
    Filed: October 30, 2006
    Publication date: March 1, 2007
    Inventors: J. Bazan, Rene de Waal Malefyt, Yong-Jun Liu, Vassili Soumelis
  • Patent number: 7071308
    Abstract: Nucleic acids encoding mammalian cytokine receptor, e.g., for cytokine IL-B50, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: July 4, 2006
    Assignee: Schering Corporation
    Inventors: Pedro A. Reche-Gallardo, Vassilli Soumelis, Yong-Jun Liu, Rene de Waal Malefyt, J. Fernando Bazan, Robert A. Kastelein
  • Publication number: 20060110386
    Abstract: Nucleic acids encoding mammalian cytokine receptor, e.g., for cytokine IL-B50, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
    Type: Application
    Filed: December 9, 2005
    Publication date: May 25, 2006
    Applicant: Schering Corporation
    Inventors: Pedro Reche-Gallardo, Vassili Soumelis, Yong-Jun Liu, Rene de Waal Malefyt, J. Bazan, Robert Kastelein
  • Patent number: 6933369
    Abstract: Nucleic acids encoding various proteases, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Grant
    Filed: January 22, 2003
    Date of Patent: August 23, 2005
    Assignee: Schering Corporation
    Inventors: Christopher G. Mueller, Serge J. E. Lebecque, Yong-Jun Liu, Lynette M. Dowling, Constance F. Huffine, Daniel M. Gorman
  • Patent number: 6913924
    Abstract: Dendritic cell subsets, and various methods of making and using same are provided. In particular, methods for making a defined subset of dendritic cells are provided.
    Type: Grant
    Filed: October 9, 2003
    Date of Patent: July 5, 2005
    Assignee: Schering Corporation
    Inventors: Bianca Blom, Yong-Jun Liu
  • Publication number: 20050112659
    Abstract: Nucleic acids encoding mammalian Toll-like receptors (TLRs) have been identified in human cells. Recombinantly produced TLRs are used in the preparation of antibodies that are capable of binding to the TLRs. The antibodies are advantageously used in the prevention and treatment of septic shock, inflammatory conditions, and viral infections.
    Type: Application
    Filed: October 28, 2004
    Publication date: May 26, 2005
    Inventors: Gerard Hardiman, Fernando Rock, J. Bazan, Robert Kastelein, Stephen Ho, Yong-Jun Liu
  • Patent number: 6890734
    Abstract: Nucleic acids encoding mammalian cytokine receptor, e.g., for cytokine IL-B50, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: May 10, 2005
    Assignee: Schering Corporation
    Inventors: Pedro A. Reche-Gallardo, Vassilli Soumelis, Yong-Jun Liu, Rene de Waal Malefyt, J. Fernando Bazan, Robert A. Kastelein
  • Publication number: 20050048054
    Abstract: Provided are methods of modulating activity of regulatory T cells, CD4+ T cells, and CD8+ T cells. Also provided are methods of treating immune disorders.
    Type: Application
    Filed: July 8, 2004
    Publication date: March 3, 2005
    Inventors: Shino Hanabuchi, Rene De Waal Malefyt, Yong-Jun Liu
  • Publication number: 20050014199
    Abstract: Nucleic acids encoding mammalian cytokine receptor, e.g., for cytokine IL-B50, purified proteins and fragments thereof Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
    Type: Application
    Filed: August 25, 2004
    Publication date: January 20, 2005
    Applicant: Schering Corporation
    Inventors: Pedro Reche-Gallardo, Vassilli Soumelis, Yong-Jun Liu, Rene de Waal Malefyt, J. Bazan, Robert Kastelein
  • Publication number: 20040091970
    Abstract: Purified genes encoding cytokines from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Application
    Filed: June 20, 2003
    Publication date: May 13, 2004
    Applicant: Schering Corporation, a New Jersey corporation
    Inventors: J. Fernando Bazan, Rene de Waal Malefyt, Yong-Jun Liu, Vassili Soumelis
  • Publication number: 20040071662
    Abstract: Dendritic cell subsets, and various methods of making and using same are provided. In particular, methods for making a defined subset of dendritic cells are provided.
    Type: Application
    Filed: October 9, 2003
    Publication date: April 15, 2004
    Applicant: Schering Corporation, a New Jersey corporation
    Inventors: Bianca Blom, Yong-Jun Liu
  • Patent number: 6660523
    Abstract: Dendritic cell subsets, and various methods of making and using same are provided. In particular, methods for making a defined subset of dendritic cells are provided.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: December 9, 2003
    Assignee: Schering Corporation
    Inventors: Bianca Blom, Yong-Jun Liu
  • Publication number: 20030149245
    Abstract: Nucleic acids encoding various proteases, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Application
    Filed: January 22, 2003
    Publication date: August 7, 2003
    Inventors: Christopher G. Mueller, Serge J.E. Lebecque, Yong-Jun Liu, Lynette M. Dowling, Constance F. Huffine, Daniel M. Gorman
  • Publication number: 20030099947
    Abstract: Purified genes encoding cytokines from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Application
    Filed: September 25, 2001
    Publication date: May 29, 2003
    Inventors: J. Fernando Bazan, Rene de Waal Malefyt, Yong-Jun Liu, Vassili Soumelis
  • Publication number: 20030032090
    Abstract: Nucleic acids encoding mammalian Toll-like receptors (TLRs) have been identified in human cells. Recombinantly produced TLRs are used in the preparation of antibodies that are capable of binding to the TLRs. The antibodies are advantageously used in the prevention and treatment of septic shock, inflammatory conditions, and viral infections.
    Type: Application
    Filed: September 10, 2001
    Publication date: February 13, 2003
    Applicant: Schering Corporation, a New Jersey Corporation
    Inventors: Gerard T. Hardiman, Fernando L. Rock, Bazan J. Fernando, Robert A. Kastelein, Stephen W.K. Ho, Yong-Jun Liu
  • Publication number: 20030003579
    Abstract: Methods of effecting particular dendritic cell subsets. In particular, methods for inducing responses in defined subsets of dendritic cells are provided.
    Type: Application
    Filed: October 22, 2001
    Publication date: January 2, 2003
    Inventors: Norimitsu Kadowaki, Yong-Jun Liu
  • Publication number: 20020173623
    Abstract: Nucleic acids encoding mammalian cytokine receptor, e.g., for cytokine IL-B50, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
    Type: Application
    Filed: November 8, 2001
    Publication date: November 21, 2002
    Inventors: Pedro A. Reche-Gallardo, Vassilli Soumelis, Yong-Jun Liu, Rene de Waal Malefyt, J. Fernando Bazan, Robert A. Kastelein
  • Publication number: 20020098587
    Abstract: Dendritic cell subsets, and various methods of making and using same are provided. In particular, methods for making a defined subset of dendritic cells are provided.
    Type: Application
    Filed: September 18, 2001
    Publication date: July 25, 2002
    Inventors: Bianca Blom, Yong-Jun Liu