Abstract: An outbound packet is detected from a client device of a first spoke destined to a client device of a second spoke over SD-WAN through a hub connecting the first and second spokes with IPSec tunneling. The first spoke is on a local enterprise network, the second spoke is on a remote enterprise network and the hub is on wide area network, and each of the first spoke, the second spoke and the hub are each ADVPN2.0 compatible. Responsive to the detection, a health check is performed on the remote spoke. A path is selected between a local NAT device of multiple NAT devices of the first spoke and a remote NAT device of the multiple remote NAT devices of the second spoke, based on link quality data of the response. A NAT hole is punched between a selected local NAT and a selected inbound NAT and an IPSec tunnel is established, independent of the hub.

Abstract: An isolator for separating a power line into a power consumption side and a transmission side can be used to enhance power line communication (PLC) and to prevent time varying noise and impedance of the power consumption side in a communication frequency band from affecting communication effects, wherein the isolator often has a larger inductance value. This disclosure provides a special circuit, wherein the inductor is kept at a low inductance value when a low frequency alternating current flows through the inductor, but is kept at a high inductance value in the communication frequency band, and a small core can be used to satisfy requirements of the high inductance value in the communication frequency band.

Abstract: A diffusiophoresis-enhanced particle deposition system can include a deposition surface and a droplet ejector connectable to a supply of particle-containing ink, where the droplet ejector is positioned to eject droplets of the particle-containing ink onto the deposition surface. An atmosphere control chamber can surround the deposition surface. A supply of a solute gas that is soluble in the particle-containing ink can be connected to the atmosphere control chamber to provide a controlled atmospheric concentration of the solute gas to droplets on the deposition surface.

Abstract: A battery connection module is provided. The battery connection module is adapted to connect a plurality of batteries, the battery connection module includes a plurality of busbars and a single layer wiring flexible circuit board. The plurality of busbars are used to connect a plurality of batteries in series. The single layer wiring flexible circuit board has multiple connector connecting points positioned to a front end portion thereof and a multiple traces, front ends of the multiple traces are respectively connected to the multiple connector connecting points, and rear end connecting points of some of the multiple traces are electrically and mechanically connected to the plurality of busbars, the multiple traces includes at least one rounding trace and at least one rounded trace, the rounding trace rounds the rear end connecting point of the rounded trace so as to round from one side of the at least one rounded trace to the other side of the at least one rounded trace.

Abstract: The present invention relates to matriptase antibodies and immunoconjugates of matriptase antibodies with cytotoxic agents and the use thereof for killing or inhibiting the growth of matriptase-expressing cancer cells, such as those of multiple myeloma and breast cancers. In particular, immunoconjugates comprising a matriptase monoclonal antibody and anticancer agents such as auristatin, including monomethyl auristatin E (MMAE) and monomethyl auristatin F (MMAF) are introduced, which have potent antitumor activity in vivo. Moreover, importantly; there was no weight loss or other evidence of toxicity in the animals, indicating that no significant free drug was released into the circulation from the conjugate. The present invention also provides compositions comprising these new immunoconjugates and use of them for treatment of malignancies comprising cells that express matriptase.

Abstract: The present application discloses a light sensor circuit comprising a first amplifier, a second amplifier and an active load. An integration circuit is formed by the operation of this light sensor circuit and connected to a photodiode. The cathode of the photodiode is controlled to maintain an identical or approximate voltage level with the anode of the photodiode, which significantly reduces the influence of the dark current from the photodiode. Consequently, when applied to an analog-to-digital conversion device, the light sensor circuit effectively maintains the performance and accuracy of the device. Additionally, this design significantly reduces circuit complexity and manufacturing costs.

Abstract: A workpiece spindle comprises a spindle, a spindle motor and an actuator. The spindle is dynamically connected to the spindle motor and has a first channel and a second channel connected to the first channel. The first channel is assembled with a lathe center, the actuator is provided with an actuating rod disposed outside the spindle corresponding to the second channel. The workpiece spindle limits rotation of the spindle by displacing the actuating rod of the actuator by a first actuation distance relative to the second channel, and the workpiece spindle drives the lathe center to displace in the first channel by displacing the actuating rod of the actuator by a second actuation distance relative to the second channel. Thereby, machining statuses of the lathe center are integrated for convenient operation, and the lathe center is driven and displaced in the channel to facilitate replacement.

Abstract: A local spoke is configured with a hub that serves at least one remote spoke equipped with a plurality of IPSEC endpoint interfaces for routing traffic according to a routing table of the hub. A first routing path is received to the at least one remote spoke for dynamic VPN with a first IPSEC endpoint selected by the hub based on a Reply message without consideration of first link quality of the remote spoke relative to other available links. In another embodiment, an ADVPN shortcut is established. Data packets are then transmitted using a second routing path for dynamic VPN with a second IPSEC endpoint. A new ADVPN shortcut is established for more optimal routing, based on updated link quality metrics discovered during a health check. The existing ADVPN shortcut is then allowed to expire.

Abstract: The present invention relates to anti-matriptase antibodies and immunoconjugates of anti-matriptase antibodies with cytotoxic agents and the use thereof for killing or inhibiting the growth of matriptase-expressing cancer cells, such as those of multiple myeloma and breast cancers. In particular, immunoconjugates comprising an anti-matriptase monoclonal antibody and anticancer agents such as auristatin, including monomethyl auristatin E (MMAE) and monomethyl auristatin F (MMAF) are introduced, which have potent antitumor activity in vivo. Moreover, importantly; there was no weight loss or other evidence of toxicity in the animals, indicating that no significant free drug was released into the circulation from the conjugate. The present invention also provides compositions comprising these new immunoconjugates and use of them for treatment of malignancies comprising cells that express matriptase.

Abstract: A grinding wheel changing structure of grinding machines includes a base to which a clamping device, a grinding device, a storage device, a gripping device are mounted thereon. The clamping device clamps workpieces. The grinding device is movable along two axes and includes a grinding wheel and a guard. The grinding wheel is located inside the guard. A lid is pivotably connected to the guard. The storage device has multiple grinding wheels detachably stored therein. The gripping device is located between the grinding device and the storage device. The gripping device is linearly movable and includes a gripping unit which is rotatable. By using the gripping device with its gripping unit to grasp the grinding wheel and shuttle back and forth, rotate between the grinding device and the storage device, to load and unload the grinding wheel.

Abstract: A battery connection module is provided. The battery connection module is adapted to connect a plurality of batteries, the battery connection module includes a plurality of busbars and a single layer wiring flexible circuit board. The plurality of busbars are used to connect a plurality of batteries in series. The single layer wiring flexible circuit board has multiple connector connecting points positioned to a front end portion thereof and a multiple traces, front ends of the multiple traces are respectively connected to the multiple connector connecting points, and rear end connecting points of some of the multiple traces are electrically and mechanically connected to the plurality of busbars, the multiple traces includes at least one rounding trace and at least one rounded trace, the rounding trace rounds the rear end connecting point of the rounded trace so as to round from one side of the at least one rounded trace to the other side of the at least one rounded trace.

Abstract: The present disclosure relates to a battery connection module and a battery device. The battery connection module includes a carrying tray, a plurality of busbars and a flexible circuit board. The plurality of busbars are provided to the carrying tray.

Abstract: An image processing circuit includes a receiver, at least one memory, a recognition circuit, a calculation circuit and a compensation circuit. The receiver is configured to receive a current image frame and a plurality of previous image frames. The at least one memory is configured to store the plurality of previous image frames. The recognition circuit is configured to select a first previous image frame or a second previous image frame among the plurality of previous image frames from the at least one memory. The calculation circuit is configured to calculate a compensation value for the current image frame according to at least one of the first previous image frame and the second previous image frame by referring to a lookup table (LUT). The compensation circuit is configured to modify a current image data of the current image frame by using the compensation value.

Abstract: A battery connection module includes a carrying tray, a plurality of busbars and a flexible circuit board. The plurality of busbars are provided on the carrying tray. The flexible circuit board is provided on the carrying tray, the plurality of busbars is adjacent to the flexible circuit board, and the busbar has a notch which is formed to a side toward the flexible circuit board and a notch side plate portion which is positioned alongside the notch, the flexible circuit board has a bending arm which integrally extend out from the flexible circuit board, the bending arm is positioned in the notch of the busbar and a tip of the bending arm is electrically connected to the busbar. In some embodiments, a battery connection module further includes an output connection port provided to the carrying tray. In some embodiments, a battery connection module further includes a connector provided to the carrying tray.

Abstract: An operation method of a proximity sensor comprises: controlling a light-emitting element by a processing circuit. Such control includes a plurality of light source on and light source off operations. An optical sensor receives light and outputs a sensing signal corresponding to the intensity of the light. The processing circuit computes the sensing signal to produce a sensing result. The plurality of light source on and light source off operations includes a group having two light sources on operations and two light sources off operations. The two light sources on operations in the group or the two light sources off operations in the group are performed consecutively. In this way, the ambient light components of the light source on and off operations may cancel out each other to reduce the ambient light components contained in the sensing results.