Abstract: A method and system for picking first-break times for a seismic dataset are disclosed. The method includes generating a pre-processed seismic dataset and an initial refraction velocity model from the pre-stack seismic dataset and generating a first-break energy-enhanced seismic dataset using nonlinear beamforming applied to the pre-processed seismic dataset and the initial refraction velocity model. The methods further include estimating a refined refraction velocity model from the first-break energy-enhanced seismic dataset, and generating a post-processed seismic dataset from the refined refraction velocity model and first-break energy-enhanced seismic dataset. The methods still further include, for each pre-stack trace, determining a first-break time from the post-processed seismic dataset and the refined refraction velocity model.

Abstract: A method and system for picking first-break times for a seismic dataset are disclosed. The method includes generating a pre-processed seismic dataset and an initial refraction velocity model from the pre-stack seismic dataset and generating a first-break energy-enhanced seismic dataset using nonlinear beamforming applied to the pre-processed seismic dataset and the initial refraction velocity model. The methods further include estimating a refined refraction velocity model from the first-break energy-enhanced seismic dataset, and generating a post-processed seismic dataset from the refined refraction velocity model and first-break energy-enhanced seismic dataset. The methods still further include, for each pre-stack trace, determining a first-break time from the post-processed seismic dataset and the refined refraction velocity model.

Abstract: Provided are methods for identifying the presence or absence of a chromosome abnormality by which a cell-free sample nucleic acid from a subject is analyzed. In certain embodiments, provided are methods for identifying the presence or absence of a fetal chromosome abnormality in a nucleic acid from cell-free maternal blood.

Abstract: Provided are methods for identifying the presence or absence of a chromosome abnormality by which a cell-free sample nucleic acid from a subject is analyzed. In certain embodiments, provided are methods for identifying the presence or absence of a fetal chromosome abnormality in a nucleic acid from cell-free maternal blood.

Abstract: Provided are methods for identifying the presence or absence of a chromosome abnormality by which a cell-free sample nucleic acid from a subject is analyzed. In certain embodiments, provided are methods for identifying the presence or absence of a fetal chromosome abnormality in a nucleic acid from cell-free maternal blood.

Abstract: Provided are methods for identifying the presence or absence of a chromosome abnormality by which a cell-free sample nucleic acid from a subject is analyzed. In certain embodiments, provided are methods for identifying the presence or absence of a fetal chromosome abnormality in a nucleic acid from cell-free maternal blood.

Abstract: Provided herein are processes for rapidly identifying or determining sequence information in a sample nucleic acid by comparing sample nucleic acid sequence information to reference nucleic acid sequence information or information obtained from reference samples. Also provided are automated systems for conducting comparative sequence analyses.

Abstract: Provided are methods for identifying the presence or absence of a chromosome abnormality by which a cell-free sample nucleic acid from a subject is analyzed. In certain embodiments, provided are methods for identifying the presence or absence of a fetal chromosome abnormality in a nucleic acid from cell-free maternal blood.

Abstract: Provided herein are processes for rapidly identifying or determining sequence information in a sample nucleic acid by comparing sample nucleic acid sequence information to reference nucleic acid sequence information or information obtained from reference samples. Also provided are automated systems for conducting comparative sequence analyses.