Abstract: One aspect of the disclosure relates to a cargo delivery system comprising an autophagy targeting ligand and a target-binding ligand. In one aspect of the disclosure, by comprising an autophagy targeting ligand, cargo, which is a target-binding ligand that specifically binds to a target, is delivered to the p62 protein and autophagy is activated, so that depending on the type of target-binding ligand used, a target to be degraded can be selectively and directly removed. Accordingly, the cargo delivery system according to an aspect of the disclosure may be used in pharmaceutical compositions or food compositions for preventing, alimerating, and treating various diseases.

Abstract: A method, a computer readable medium, and an apparatus for wireless communication are provided. The apparatus may receive, via a radio frequency channel, a first data from a first human interface device at a first time slot of a frame. The apparatus may transmit the first data to a computing device. The apparatus may receive, via the radio frequency channel, a second data from a second human interface device at a second time slot of the frame. The apparatus may transmit the second data to the computing device. The apparatus may transmit, via the radio frequency channel at a third time slot of the frame, at least one of a first acknowledgment to the first data, a first lighting effect configuration data for the first human interface device, a second acknowledgment to the second data, or a second lighting effect configuration data for the second human interface device.

Abstract: Provided is a smart terminal accessory-based membership-only service platform and a method thereof. The smart terminal accessory-based membership-only service platform according to an embodiment of the present inventive concept includes: a management server for authenticating NFC information requested from a user terminal that identifies an NFC tag from a smart terminal accessory embedded with the NFC tag by means of NFC tagging, and registering the user terminal as a user of the smart terminal accessory; and a service server for registering and interconnecting the user terminal as a member in response to a request from the management server, and providing a membership-only service corresponding to the smart terminal accessory and requested from the user terminal.

Abstract: An information search method includes: obtaining search words at least including a question to be searched and obtaining an initial text vector representation of the search words; obtaining a video corresponding to the search words, and obtaining multi-modality vector representations of the video; starting from the initial text vector representation, performing N rounds of interaction between the video and the search words based on the multi-modality vector representations and a text vector representation of the search words of a current round, to generate a target fusion vector representation, where N is an integer greater than or equal to 1; and obtaining target video frames matching the question to be searched by annotating the video based on the target fusion vector representation.

Abstract: The present disclosure describes a method for forming polysilicon resistors with high-k dielectrics and polysilicon gate electrodes. The method includes depositing a resistor stack on a substrate having spaced apart first and second isolation regions. Further the method includes patterning the resistor stack to form a polysilicon resistor structure on the first isolation region and a gate structure between the first and second isolation regions, and doping the polysilicon resistor structure to form a doped layer in the polysilicon layer of the polysilicon resistor structure and source-drain regions in the substrate adjacent to the gate structure. Also, the method includes replacing the polysilicon layer in the gate structure with a metal gate electrode to form a transistor structure.

Abstract: The present disclosure provides a sliding puzzle. The sliding puzzle includes a cylindrical support and a plurality of blocks. The cylindrical support provided with two opposite bottom surfaces and a side surface connected between the two bottom surfaces, wherein the side surface is provided with a guide rail structure. Each of the blocks is mounted on the guide rail structure and can slide along the guide rail structure to change a position. The sliding puzzle in this solution can effectively decrease the possibility of loss of block parts in an assembling process of the sliding puzzle and improves the convenience of use of the sliding puzzle. Meanwhile, compared with the paper card type and plastic sliding puzzles, the sliding puzzle in this solution improves the stereo perception and the funniness. The sliding puzzle is simple in structure, convenient to assemble, and connected firmly.

Abstract: A heating patch for skin care including a substrate unit; an application electrode unit formed on the substrate unit in a predetermined pattern, and which includes a first electrode and a second electrode to which power supplied from the outside is applied; a heating unit including first and second heating electrodes, which respectively extend a predetermined length from the first and second electrodes so as to face each other at a certain length without being electrically connected, and a plurality of conductive heating materials formed to have predetermined areas in an overlapping part in which the first and second heating electrodes face each other and generate heat while allowing the first and second heating electrodes to communicate with each other during application of power; and a pair of cover members arranged on both surfaces of the substrate unit to prevent external exposure of the applied electrode unit and heating unit.

Abstract: An aerosol generating device includes a cavity into which a cigarette is inserted, a light source that emits light to the cigarette inserted in the cavity, a reuse detection sensor that receives light reflected from the cigarette, a heater that heats the cigarette inserted into the cavity, and a controller, and the controller determines whether or not to operate the heater based on a rate of increase or decrease of a sensing value received from the reuse detection sensor.

Abstract: Provided is a lithography apparatus including a wafer stage, a cable connected to the wafer stage, the cable being configured to bend based on the wafer stage moving, a support unit configured to prevent the cable from sagging, the support unit including a plurality of clamps configured to restrict movement of the cable and a connection member connecting the plurality of clamps to each other, and a protective unit under the cable, the protective unit being configured to collide with the support unit based on the wafer stage moving, wherein the protective unit includes ultra-high molecular weight polyethylene (UHMWPE).

Abstract: A display driving device includes a low-speed communication circuit configured to receive configuration data at a first data rate in a first mode; a high-speed communication circuit configured to train a communication clock signal for communication at a second data rate in a second mode, to receive image data and first control data using the communication clock signal in a third mode, and to receive second control data using the communication clock signal in a fourth mode; a control circuit configured to switch the first mode to the second mode upon completion of the first mode, to switch the second mode to the third mode upon completion of the second mode, to switch the third mode to the second mode when an abnormal state is detected in the third mode, and to switch the fourth mode to the first mode when an abnormal state is detected in the fourth mode; and a circuit configured to control pixels of a display panel to be driven according to the image data, thereby easily managing operation modes of a data dri

Abstract: Methods of forming electrochemical cells are described. In some implementations, the method can include providing an electrochemical cell having an electrode including electrochemically active material with at least about 20% to about 100% by weight of silicon. The method can include charging the electrochemical cell by providing a formation charge current at about 1 C or greater to the electrochemical cell. The method can also include discharging the electrochemical cell. In various implementations, substantially no rest of greater than about 5 minutes occurs between charging and discharging.

Abstract: A multi-wavelength entangled photon pair generation device includes: a multi-mode pump laser that radiates a broadband pump laser beam in an ultraviolet wavelength range including multiple Gaussian-distributed wavelengths; a nonlinear crystal that generates a multi-wavelength de-multiplexed entangled photon pair in a near-infrared wavelength range including multiple wavelength components corresponding to multiple Gaussian-distributed wavelengths of the broadband pump laser beam, respectively; a temperature controller that adjusts a temperature of the nonlinear crystal; and an output optical system that filters out the broadband pump laser beam from light output through the nonlinear crystal and passes the multi-wavelength de-multiplexed entangled photon pair.

Abstract: The present application relates to a peptide having protective activity against cell damage caused by particulate matter, and to uses for the peptide.

Abstract: A chip package structure includes a first chip, a second chip, and a carrier board. The first chip is disposed between the second chip and the carrier board. An active layer of the first chip is opposite to an active layer of the second chip. A first interconnection structure is disposed between the first chip and the second chip and is configured to couple the active layer of the first chip to the active layer of the second chip. A first conductor pillar is disposed in the first chip. One end of the first conductor pillar is coupled to the active layer of the first chip, and the other end of the first conductor passes through the first chip to be coupled to a circuit in the carrier board.

Abstract: Systems and method for bidirectional communication for front end modules (FEM) are disclosed. In one aspect, a bidirectional communication path tunneling through an existing communication bus between a FEM and a baseband processor is created. In a particular aspect, a driver may be hosted by an external processor and communicate with the baseband processor to effectuate the desired tunneled communication through the bus between the baseband processor and the FEM. The bidirectional communication may allow the FEM to adjust settings to optimize performance based on the information provided by the baseband processor. Likewise, information from the FEM may be used to adjust operation of the baseband processor.

Abstract: A method includes: forming, on a first substrate, a first bonding layer including a first metal oxide material in an amorphous state; forming, on a second substrate, a second bonding layer including a second metal oxide material in an amorphous state; annealing the first and second bonding layers using a laser source, so as to convert the first and second metal oxide materials to a crystalline state; forming, on the first bonding layer, a third bonding layer including a third metal oxide material in an amorphous state; forming, on the second bonding layer, a fourth bonding layer including a fourth metal oxide material in an amorphous state; bonding the first and second substrates to each other through the first to fourth bonding layers; and annealing the third and fourth bonding layers using a heat source, so as to convert the third and fourth metal oxide materials to a crystalline state.

Abstract: The present invention provides a new group of protein kinase inhibitors, aminopyrimidine derivatives, and pharmaceutically acceptable salts thereof that are useful for treating cell proliferative disease and disorder such as cancer and immune disease. The present invention provides methods for synthesizing and administering the protein kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the protein kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefore. The invention also provides useful intermediates generated during the syntheses of the aminopyrimidine derivatives.