Abstract: An omni-directional camera (a 360 degree camera) is proposed with an integrated microphone array. The primary application for such a camera is videoconferencing and meeting recording, and the device is designed to be placed on a meeting room table. The microphone array is in a planar configuration, and the microphones are located as close to the desktop as possible to eliminate sound reflections from the table. The camera is connected to the microphone array base with a thin cylindrical rod, which is acoustically invisible to the microphone array for the frequency range [50-4000] Hz. This provides a direct path from the person talking to all of the microphones in the array, and can therefore be used for sound source localization (determining the location of the talker) and beam-forming (improving the sound quality of the talker by filtering only sound from a particular direction). The camera array is elevated from the table to provide a near frontal viewpoint of the meeting participants.

Abstract: A system and method for object tracking using probabilistic mode-based multi-hypothesis tracking (MHT) provides for robust and computationally efficient tracking of moving objects such as heads and faces in complex environments. A mode-based multi-hypothesis tracker uses modes that are local maximums which are refined from initial samples in a parametric state space. Because the modes are highly representative, the mode-based multi-hypothesis tracker effectively models non-linear probabilistic distributions using a small number of hypotheses. Real-time tracking performance is achieved by using a parametric causal contour model to refine initial contours to nearby modes. In addition, one common drawback of conventional MHT schemes, i.e., producing only maximum likelihood estimates instead of a desired posterior probability distribution, is addressed by introducing an importance sampling framework into MHT, and estimating the posterior probability distribution from the importance function.

Abstract: Transgenic mice that produce high levels of humanized antibodies are described. Targeted gene replacement exchanges constant regions of the mouse immunoglobulin heavy and light chain genes with human genes, either through conventional gene targeting, or by use of the bacteriophage-derived Cre-loxP recombination system. The transgenic animals undergo antibody affinity maturation, and a class switch from the native immunoglobulin to the humanized form.

Abstract: Automatic detection and tracking of multiple individuals includes receiving a frame of video and/or audio content and identifying a candidate area for a new face region in the frame. One or more hierarchical verification levels are used to verify whether a human face is in the candidate area, and an indication made that the candidate area includes a face if the one or more hierarchical verification levels verify that a human face is in the candidate area. A plurality of audio and/or video cues are used to track each verified face in the video content from frame to frame.

Abstract: Transgenic mice that produce high levels of humanized antibodies are described. Targeted gene replacement exchanges constant regions of the mouse immunoglobulin heavy and light chain genes with human genes, either through conventional gene targeting, or by use of the bacteriophage-derived Cre-loxP recombination system. The transgenic animals undergo antibody affinity maturation, and a class switch from the native immunoglobulin to the humanized form.

Abstract: An automated system and method for producing videos using expert video production rules. The automated video production system and method of the present invention is particularly well-suited for the online publishing of lectures. The system of the present invention includes a camera system for capturing the lecture, such as an audience-tracking camera and a non-intrusive lecturer-tracking camera. Moreover, each camera may be controlled by a cinematographer. Tracking of a subject is performed using a history-based, reduced-motion tracker that sets up a camera shot based on the subject's movement history and leaves the shot fixed until the camera is switched. The system also includes a virtual director module having a probabilistic finite state machine (FSM) module that uses probabilistic rules and the expert video production rules to determine a current camera view.

Abstract: An automated system and method for broadcasting meetings over a computer network. The meeting is filmed using an omni-directional camera system and capable of being presented to a viewer both live and on-demand. The system of the present invention includes an automated camera management system for controlling the camera system and an analysis module determining the location of meeting participants in the meeting environments. The method of the present invention includes using the system of the present invention to broadcast an event to a viewer over a computer network. In particular, the method includes filming the event using an omni-directional camera system. Next, the method determines the location of each event participant in the event environment. Finally, a viewer is provided with a user interface for viewing the broadcast event. This user interface allows a viewer to choose which event participant that the viewer would like to view.