Abstract: Provided is a conjugate for photodynamic diagnosis or treatment in which a peptide binds with a photosensitizer via an intracellularly degradable linkage, and a composition for photodynamic diagnosis or treatment including the same. The conjugate generates no fluorescent signal and reactive oxygen in normal tissues or during the circulation in the blood by quenching a fluorescent signal and reactive oxygen generation ability of the photosensitizer. After the conjugate is selectively absorbed into target cells, a linker is degraded in cells to increase the distance between tryptophan included in the peptide and the photosensitizer, and the quenching action is terminated to generate a strong fluorescence signal and induce active generation of reactive oxygen. The conjugate has high tissue permeability, shows a high photodynamic therapeutic effect in only target cells while being safe in normal cells, and can obtain a good diagnostic image having a high ratio of target signal to background.

Abstract: One or more embodiments relate to an aerosol generating article including: a first portion including an aerosol generating element; a second portion including a cooling element; a third portion including a tobacco element; and a fourth portion including a filter element, wherein the first through fourth portions are sequentially arranged in a longitudinal direction of the aerosol generating article.

Abstract: A wafer level package includes: a substrate; an element portion disposed on one surface of the substrate; a cap disposed on the substrate to cover the element portion; a connection portion electrically connected to the element portion; and a bonding portion disposed on an outer side of the connection portion, wherein the bonding portion is disposed on a first surface of one of the substrate and the cap, wherein one end portion of the connection portion is disposed on a second surface having a step difference from the first surface, and wherein the connection portion and the bonding portion are formed of a eutectic material.

Abstract: The present invention relates to a lighting device and a control method therefor. The lighting device according to the present invention comprises: a light source unit comprising one or more light emitting elements; a first body to which the light source unit is mounted; a second body; a sensor unit for sensing at least one of a relative posture and a relative position of the first body to the second body; and a control unit for controlling the light emitting operation of the light source unit on the basis of at least one of the relative posture and the relative position of the first body.

Abstract: A message display method includes: caching, by a server, a message display page according to each original URL, extracting a fingerprint feature, and generating an alternative URL, then detecting a display status of each message at a preset time interval and marking the display status, and when receiving a display information obtaining request from a client, sending the fingerprint feature, the original URL, or the alternative URL of each message to the client according to a currently marked display status; and when receiving a message access request of a user, determining, by the client, a type of a corresponding URL, and if the corresponding URL is an alternative URL, displaying the message to the user, or if the corresponding URL is an original URL, determining whether the message is displayed normally, and if yes, displaying the message to the user.

Abstract: A display apparatus includes a base substrate, a light emitting structure disposed on the base substrate, and a thin film encapsulation layer disposed on the light emitting structure and including at least one inorganic layer and at least one organic layer. The at least one inorganic layer includes a high density layer having a density of greater than or equal to about 2.0 g/cm3 and a low density layer having a density of less than about 2.0 g/cm3. The high density layer and the low density layer are in contact with each other.

Abstract: This application discloses a method for updating a virtual environment picture performed by a computer device. The method includes: displaying a first virtual environment picture of a virtual environment using a first observation position as an observation center, wherein a virtual character is located at a first position in the first virtual environment picture; in response to receiving a first directional operation on the virtual character, displaying a skill indicator in accordance with the first directional operation; and when at least a portion of the skill indicator is going to exceed the first virtual environment picture, replacing the first virtual environment picture with displaying a second virtual environment picture, wherein the virtual character is relocated from the first position in the first virtual environment picture to a second position in the second virtual environment picture so as to present the skill indicator in the second virtual environment picture.

Abstract: A method for unlocking the electronic device includes displaying a screen for verifying a registered user, determining whether a user is a registered user in the electronic device based on a user input to the screen for verifying a registered user, and unlocking the electronic device when the user is determined to be the registered user.

Abstract: Provided is an aerosol generating apparatus including: a susceptor configured to heat an aerosol generating article inserted into an accommodation space of the aerosol generating apparatus; an induction coil arranged around the susceptor and configured to heat the susceptor by induction heating; a switching module configured to switch an electrical path of the induction coil; and a controller electrically connected to the switching module and configured to detect insertion of the aerosol generating article on the basis of a change in an inductance of the induction coil by setting a control mode for the induction coil to a reception mode, and when the insertion of the aerosol generating article is detected, switch the control mode to a transmission mode for activating the induction heating, via the switching module.

Abstract: An embodiment of the present disclosure discloses tobacco material including: a center portion including a flavor material; and an outer portion including a tobacco mixture, wherein the outer portion surrounds the center portion.

Abstract: Dental bulk blocks for cutting machining are provided. The dental bulk block is a glass ceramic block having a structure in which crystalline phases including lithium disilicate as a main crystalline phase and lithium phosphate and at least one of cristobalite and tridymite as additional crystalline phases in an amorphous glass matrix. The dental bulk block is a functionally graded material (FGM) having gradations of size in the main crystalline phase along a depth direction thereof and having no interface at a gradation value change point at which a gradation value of size in the main crystalline phase changes. The dental bulk block is useful for the manufacture of artificial dental prostheses similar to natural teeth. Therefore, the present disclosure provides the effect of reducing the time and process of manufacturing artificial teeth protheses and increasing structural stability in teams of force distribution by functionally grading physical properties.

Abstract: Methods, systems, and computer program products for de-duplicating data in executable files in a container image are disclosed. The method may include receiving a request to read a file in a first layer in a container image including a plurality of layers, wherein the file is a delta file which is from an updated executable file based on a base executable file, the base executable file is in a lower layer than the first layer in the container image, and the delta file includes block mappings between the updated executable file and the base executable file and different data between the two files, and blocks included in the two files are based on respective file structure. The method may also include restoring the updated executable file based on the delta file and the base executable file. The method may further include returning data in the updated executable file.

Abstract: An aerosol generating device includes: a housing including a hole for receiving an aerosol generating article and a guide apart from the hole; and a cover configured to move along the guide between a first position and a second position to open or close the hole, wherein the hole is open when the cover is located in the first position, and the hole is closed when the cover is located in the second position.

Abstract: A device for controlling a user interface may include a sensor configured to acquire information associated with a passenger of a vehicle, a user interface device configured to receive at least one user input of the passenger, and a processor. The processor may monitor, based on the information associated with the passenger, the passenger, determine, based on an abnormality associated with an appearance of the passenger, a passenger type for the passenger, and provide, based on the passenger type for passenger and via the user interface device, a user interface associated with the passenger type, wherein the user interface associated with the passenger type is configured to reduce a task completion time for the passenger type.

Abstract: A dental bulk block for machining, which is a glass-ceramic block including a crystalline phase in an amorphous glass matrix. The bulk block is a functionally graded material including crystalline phases where among the crystalline phases, a main crystalline phase is lithium disilicate, and an additional crystalline phase includes quartz, lithium phosphate, and at least one selected from among cristobalite and tridymite, in which the main crystalline phase has a size gradient with respect to a depth, and no interface is present at a point where a size gradient value of the main crystalline phase changes. Thus, the bulk block is useful in manufacturing artificial tooth prostheses that are similar to natural teeth and thus can not only reduce the time and processes for manufacturing artificial tooth prostheses but also obtain the effect of enhancing structural stability in terms of force distribution based on functionally graded mechanical characteristics.

Abstract: An optical imaging system includes a first lens, a second lens, a third lens, a fourth lens, a fifth lens, and a sixth lens sequentially disposed on an optical axis from an object side toward an image side. A distance from an object-side surface of the first lens to an imaging plane of an image sensor is TTL, an overall focal length of an optical system including the first to sixth lenses is F, and TTL/F?0.83. An optical axis distance between the second lens and the third lens is D23, an optical axis distance between the third lens and the fourth lens is D34, and 2.2<D23/D34<5.4.

Abstract: An embodiment includes generating a caller list of callers that issue requests for calling a designated program at runtime. The embodiment also includes generating an authorized caller list of authorized callers allowed to call the designated program, wherein the authorized callers are selected from among callers on the caller list. The embodiment also includes generating an authorization key for each of the authorized callers that the designated program will require as a condition for completing call requests.

Abstract: A vibration apparatus comprises a lower vibration structure, an upper vibration structure on the lower vibration structure, and an adhesive member between the lower vibration structure and the upper vibration structure. The lower vibration structure and the upper vibration structure are configured to generate sound waves having different frequencies.

Abstract: A display device includes a semiconductor layer positioned on a substrate and including a driving transistor and a plurality of transistors; a gate conductive layer positioned on the semiconductor layer; and a data conductive layer positioned on the gate conductive layer. The driving transistor has a linear shape in which a plurality of grooves are formed.

Abstract: The present invention relates to monobactam compounds of Formula I: and pharmaceutically acceptable salts thereof. The present invention also relates to compositions which comprise a monobactam compound of structural formula I or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of structural formula I, either alone or in combination with a therapeutically effective amount of a second beta-lactam antibiotic.