Abstract: A cordycepin-based derived compound with an anti-tumor effect, and a structure of the compound is as shown in formula I; a cordycepin derivative and a pharmaceutical composition thereof provided by the invention have a good anti-tumor proliferation effect; compared with a parent drug, the cordycepin derivative has better affinity to cell membranes, so that a half-life period of in-vivo metabolism of the drug is longer, and in-vivo remaining time of the drug is longer; compared with other nucleoside anti-tumor drugs, the cordycepin derivative and the pharmaceutical composition thereof provided by the invention have wider types and action ranges of tumors, have excellent inhibition effects on a gastric cancer, a pancreatic cancer, a liver cancer, a small cell lung cancer, a colorectal cancer, melanoma, an ovarian cancer and the like, and have lower side effects and better curative effects.

Abstract: A lattice-based proxy signature method, apparatus and device, a lattice-based proxy signature verification method, apparatus and device, and a storage medium. Polynomials are randomly selected in rings to calculate public and private keys of nodes, and the magnitudes of proxy public and private keys are the same as the magnitudes of public and private keys of an original signer. Therefore, compared with existing proxy signature schemes, the present application has smaller lengths of public and private keys and higher storage efficiency. Proxy signature information generated in the present application shows a signature of the original signer and also shows a signature of a proxy signer. Once a proxy signature is created, the proxy signature cannot be repudiated by the proxy signer, and has strong non-repudiation and strong unforgeability. The proxy signature method has the advantage of resisting quantum computer attack.

Abstract: Methods of forming devices comprise forming a dielectric layer on a substrate, the dielectric layer comprising at least one feature defining a gap including sidewalls and a bottom. A self-assembled monolayer (SAM) is formed on the bottom of the gap, and a barrier layer is formed on the SAM before selectively depositing a metal liner on the barrier layer. The SAM is removed after selectively depositing the metal liner on the barrier layer.

Abstract: A single-phase permanent magnet synchronous motor and dust collector. The single-phase permanent magnet synchronous motor includes a plurality of stator teeth, the plurality of stator teeth include at least: a first-type and second-type stator tooth; the first-type and second-type stator teeth enclose an annular working cavity for accommodating a rotor part, where the size of a central angle corresponding to a first contour line of an end face of the first-type stator tooth facing the rotor part is different from the size of a central angle corresponding to a second contour line of an end face of the second-type stator tooth facing the rotor part. The motor has a significantly reduced cogging torque, a greatly reduced torque ripple, and an obviously increased motor output torque. The single-phase permanent magnet synchronous motor is small in size, light in weight, simple in structure, convenient for large-scale manufacture and low in manufacturing cost.

Abstract: The present disclosure presents a device and method for calculating a change in CO2 storage capacity before and after drying, wherein the method comprises the following steps: S1: acquire a target stratum core and prepare a formation water sample and a gaseous CO2 sample; S2: measure the content of the saturated condensate water of the gaseous CO2 sample under a target formation condition; S3: saturate formation water for the target stratum core; S4: perform displacement experiments until a water saturation of a core at the target stratum reaches saturation of irreducible water in an actual stratum, and record a core porosity ?0 at this time; S5: continue the displacement experiment until all the formation water in the core of the target stratum has evaporated, and record the core porosity ?1 at this time; S6: calculate a drying radius of reservoir and the change of CO2 storage capacity after reservoir drying.

Abstract: The present application relates to an oral irrigator, the oral irrigator includes at least a main body, a partition wall, a sterilization portion, and a control main board. By providing the partition wall, the first cavity and the second cavity are separated from each other, and the spray head is separately accommodated in the second cavity, and the first cavity is provided with the sterilization portion corresponding to the second cavity. The sterilization portion includes a UV lamp module. The second cavity and the spray head are sterilized through the UV lamp module, which effectively reduces the secondary pollution of the flushing fluid.

Abstract: Disclosed is a method for evaluating the underground hydrogen storage (UHS) capacity in porous media of depleted gas reservoirs using CO2 as cushion gas, including the following steps: S1: obtaining physical parameters required for UHS capacity evaluation based on geological and production data of the target depleted gas reservoir; S2: calculating the cap-rock breakthrough pressure and fault-slip pressure of the UHS based on the cap and fault properties of the target depleted gas reservoir to further estimate the highest operating pressure of the UHS; S3: developing the H2—CO2—CH4 multi-component material balance equation in underground porous media by considering the dissolution of three components in formation water; S4: substituting the parameters obtained from S1 and S2 into the multi-component material balance equation to calculate the proportion of different gas components in the pore space to finally determine the UHS capacity of the target depleted gas reservoir.

Abstract: Disclosed is a method for evaluating the underground hydrogen storage (UHS) capacity in porous media of depleted gas reservoirs using CO2 as cushion gas, including the following steps: S1: obtaining physical parameters required for UHS capacity evaluation based on geological and production data of the target depleted gas reservoir; S2: calculating the cap-rock breakthrough pressure and fault-slip pressure of the UHS based on the cap and fault properties of the target depleted gas reservoir to further estimate the highest operating pressure of the UHS; S3: developing the H2—CO2—CH4 multi-component material balance equation in underground porous media by considering the dissolution of three components in formation water; S4: substituting the parameters obtained from S1 and S2 into the multi-component material balance equation to calculate the proportion of different gas components in the pore space to finally determine the UHS capacity of the target depleted gas reservoir.

Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of PI3K-? enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with PI3K-? signaling with the compounds and compositions of the disclosure.

Abstract: A burrowing apparatus may comprise an anterior segment and a posterior segment coupled by a linear actuator that is configured to extend and contract the distance between the anterior segment and the posterior segment to effectuate horizontal translation of the burrowing apparatus in a granular medium. The anterior segment may further comprise a conical tip. The conical tip may be configured to rotate relative to the anterior segment, and the conical tip may be an auger. The rotation of the conical tip while the linear actuator extends and contracts may create kinetic asymmetry that may be beneficial to the net horizontal translation in the granular medium. The burrowing apparatus may be advantageously used in applications, for example, in geotechnical subsurface investigation, extraterrestrial exploration, underground contamination detection, and precision agriculture.

Abstract: The present invention discloses a welding method of a demetallized ceramic substrate having a surface capillary microgroove structure. The demetallized ceramic substrate includes a ceramic substrate main body and surface capillary microstructures. The surface capillary microstructures are arranged on two lateral sides of the ceramic substrate main body and the surface capillary microstructures specifically are capillary microgrooves. The welding method includes the following steps: fixing a chip to an upper surface of the demetallized ceramic substrate having the surface capillary microgroove structure, fixing the ceramic substrate with the chip to a printed circuit board having a bonding pad, and placing melted solder on the bonding pad, and driving the solder to ascend to an electrode of the chip from the bonding pad in a lower layer by means of a capillary force, thereby realizing an electrical connection between the chip and the printed circuit board.

Abstract: The present disclosure provides a video generation method and apparatus, computer device, and storage medium, wherein the method comprises: generating a virtual three-dimensional scene, the virtual three-dimensional scene including at least one target object; in response to performing an event editing operation on the target object, generating an event stream corresponding to the target object, the event stream including: event information respectively corresponding to a plurality of nodes, wherein the event information is determined based on the event editing operation and is used for describing an event action executed by the target object; controlling the target object to execute an event action corresponding to the event information in the virtual three-dimensional scene based on the event information respectively corresponding to the plurality of nodes in the event stream, and acquiring a first target video of the target object when controlling the target object to execute the event action.

Abstract: Methods and systems for testing retrograde condensation damage in a near well zone of a condensate gas reservoir with a high condensate content are provided. The device comprises a long rock core holder, a first two-way valve, a second two-way valve, a first single-way valve, a second single-way valve, a third single-way valve, a fourth single-way valve, a first three-way valve, a second three-way valve, a third three-way valve, a confining pressure pump, a confining pressure gauge, a vacuum pump, a high-pressure high-precision displacement pump, a first intermediate container, an outlet pressure gauge, a displacement pump, a back pressure valve, a gas meter, a second intermediate container, an inlet pressure gauge, a test tube, a constant temperature oven, a gas flowmeter, a gas chromatograph, a six-way valve, a sample preparation device, and a thermostatic chamber.

Abstract: This invention provides flame retardant compositions comprised of or formed from components comprising a sulfur-containing compound and at least one isocyanate-reactive brominated flame retardant.