Abstract: Disclosed herein are novel compounds for treating apicomplexan parasite related disorders, methods for their use; cell line and non-human animal models of the dormant parasite phenotype and methods for their use in identifying new drugs to treat apicomplexan parasite related disorders, and biomarkers to identify disease due to the parasite and its response to treatment.

Abstract: In the turbine of a gas turbine engine, disk cavities exist between rotor and stator assemblies. These disk cavities enable hot gas from the hot gas flow path to ingress between the rotor and stator assemblies with detrimental effects to the durability of the turbine. Thus, a flow discourager is disclosed that can be integrated into the platform of a stator assembly that is downstream from a rotor assembly. The flow discourager comprises a continuous external surface that defines a recirculation zone within a disk cavity that is aft to a rotor assembly to circulate the hot gas back out into the hot gas flow path.

Abstract: In the turbine of a gas turbine engine, disk cavities exist between rotor and stator assemblies. These disk cavities enable hot gas from the hot gas flow path to ingress between the rotor and stator assemblies with detrimental effects to the durability of the turbine. Thus, a flow discourager is disclosed that can be integrated into the platform of a stator assembly that is downstream from a rotor assembly. The flow discourager comprises a continuous external surface that defines a recirculation zone within a disk cavity that is aft to a rotor assembly to circulate the hot gas back out into the hot gas flow path.

Abstract: In the turbine of a gas turbine engine, disk cavities exist between stator and rotor assemblies. These disk cavities enable hot gas from the hot gas flow path to ingress between the stator and rotor assemblies with detrimental effects to the durability of the turbine. Thus, a flow discourager is disclosed that can be mounted to the stator assembly. The flow discourager comprises a continuous external surface that defines a recirculation zone within the disk cavities to circulate the hot gas back out into the hot gas flow path.

Abstract: A handheld pneumatic medical device, such as a dentist handpiece, is provided for rotating a bur about an axis. Importantly, the device utilizes the boundary layer effect to transfer energy from the fluid flow to rotation of the bur. As a result, the device is operated without creating high decibel noise. Structurally, the device includes a housing defining a chamber, and a hub mounted for rotation in the chamber. When engaged with the hub, the bur passes through a distal aperture in the housing. The housing is further provided with a port for introducing a fluid into the chamber substantially tangential to the axis. Also, the device includes disks connected to the hub and substantially perpendicular to the axis. Operationally, boundary layer effect forces between the fluid flow and the disks cause the hub and the bur to rotate about the axis.

Abstract: A robust multiple-walled, multi-pass, high cooling effectiveness cooled turbine vane or blade designed for ease of manufacturability, minimizes cooling flows on highly loaded turbine rotors. The vane or blade design allows the turbine inlet temperature to increase over current technology levels while simultaneously reducing turbine cooling to low levels. A multi-wall cooling system is described, which meets the inherent conflict to maximize the flow area of the cooling passages while retaining the required section thickness to meet the structural requirements. Independent cooling circuits for the vane or blade's pressure and suction surfaces allow the cooling of the airfoil surfaces to be tailored to specific heat load distributions (that is, the pressure surface circuit is an independent forward flowing serpentine while the suction surface is an independent rearward flowing serpentine). The cooling air for the independent circuits is supplied through separate passages at the base of the vane or blade.

Abstract: A robust multiple-walled, multi-pass, high cooling effectiveness cooled turbine vane or blade designed for ease of manufacturability, minimizes cooling flows on highly loaded turbine rotors. The inventive vane or blade design allows the turbine inlet temperature to increase over current technology levels while simultaneously reducing turbine cooling to low levels. The invention comprises a complex multi-wall cooling system, which meets the inherent conflict to maximize the flow area of the cooling passages while retaining the required section thickness to meet the structural requirements. Independent cooling circuits for the vane or blade's pressure and suction surfaces allow the cooling of the airfoil surfaces to be tailored to specific head load distributions (that is, the pressure surface circuit is an independent forward flowing serpentine while the suction surface is an independent rearward flowing serpentine).

Abstract: A computer-facsimile system having separately a sending device and a receiving device, which devices are connected to the computer through a connecting device. Accordingly, the computer-facsimile system comprises a sending device of the facsimile system, a receiving device, and a connecting device connected to the sending device, the receiving device and the computer.

Abstract: The present invention comprises a process for the removal of oxides of nitrogen and sulfur from a gas mixture containing those species by exposure of the gas mixture to ultraviolet radiation having a wavelength below 220 nanometers.

Abstract: The present invention comprises a process for the removal of oxides of nitrogen and sulfur from a gas mixture containing those species by exposure of the gas mixture to ultraviolet radiation having a wavelength below 200 nanometers in absence of ammonia.

Abstract: A method and apparatus for in-process transient spectroscopic analysis of a molten metal, wherein a probe containing a pulsed high-power laser producing a pulsed laser beam having a substantially triangular pulse waveshape is immersed in the molten metal and irradiates a representative quantity of the molten metal. The pulsed laser beam vaporizes a portion of the molten metal to produce a plasma plume having an elemental composition representative of the elemental composition of the molten metal. Before the plasma plume reaches thermal equilibrium shortly after termination of the laser pulse, a spectroscopic detector in the probe detects spectral line reversals, as caused by absorption of radiation emitted by the hotter inner portion of the plasma plume to relatively coller outer portions of the plasma plume, during a short first time window.

Abstract: Apparatus which can be used for producing negative ions in a gaseous or liquid fluid is disclosed, as well as methods of using the apparatus to determine electron attachment parameters, to identify species in the fluid, or to separate selected species from the fluid. The apparatus comprises a photoelectron emitter, including a UV light source, which can be operated in pulsed or continuous modes, and a photocathode; in addition, a radially-spaced, coaxial negative ion collector, including a negative ion receiving plate, at least one of the photocathode and the receiving plate having cylindrical configuration.