Abstract: Disclosed herein are systems and methods based on tumor infiltrating leukocyte (TIL) fractal geometry to predict clinical implications in breast cancer samples. Using machine learning techniques, an algorithmic classifier is constructed and trained on a cohort of tumor images (e.g. radiographic, immunohistochemical (IHC), and H&E images) to discriminate between TILs and cancer cells, and breast cancer samples are classified based on TIL fractal geometry/anatomic distribution in the tumor stroma. Fractal geometry-directed reassessment of classifications may prompt tumor type reclassification resulting in altered cancer therapy.

Abstract: A vehicle parallel diagnosis method and apparatus, a coordinator, a system, and a medium, relating to the technical field of vehicle diagnosis, are disclosed. The method includes: receiving a diagnostic request message transmitted by a random client; detecting a current diagnostic state of a diagnostic server after the diagnostic request message is received, the current diagnostic state including a completed state and an uncompleted state; and forwarding, when the current diagnostic state is the completed state, the diagnostic request message to the diagnostic server via a target routing controller, otherwise controlling the random client to retransmit the diagnostic request message after a target delay duration until the diagnostic server is in the completed state, and forwarding the diagnostic request message to the diagnostic server via the target routing controller so as to process the diagnostic request message.

Abstract: A data processing method and apparatus are disclosed. The method includes: obtaining a sample dataset, where each sample in the sample dataset includes a first label; dividing the sample dataset into K sample sub-datasets, determining a group of data from the K sample sub-datasets as a test dataset, and using sample sub-datasets other than the test dataset as a train dataset; training the classifier by using the train dataset, and classifying the test dataset by using a trained classifier, to obtain a second label of each sample in the test dataset; obtaining a first indicator and a first hyper-parameter at least based on the first label and the second label; obtaining a loss function of the classifier at least based on the first hyper-parameter, where the loss function is used to update the classifier; and completing training of the classifier when the first indicator meets a preset condition.

Abstract: A transmission and drive system comprises an input end connected to a driving device, an output end connected to a rear wheel, a gear transmission mechanism and a belt driven transmission mechanism. A unidirectional transmission mechanism is connected to the rear wheel with the unidirectional transmission mechanism driving the rear wheel. The transmission provides power output by the driving device, transmits power to the pulley transmission mechanism by the gear transmission mechanism, and the pulley transmission mechanism drives the rear wheel to rotate the unidirectional transmission mechanism, such that the vehicle moves forward. Noise dampening plates are provided to reduce noise emanating from the transmission. In addition, a belt tensioning system is provided to maintain consistent tension on the belt.

Abstract: A signal transmission structure for speaker includes a base having two outgoing lead grooves provided on the same side thereof; a magnet member arranged on the base; a voice coil movably disposed over the magnet member; two tinsel leads respectively having an end connected to two opposite sides of the voice coil and another end set in the two outgoing lead grooves; and a signal connection board disposed in the base with two tinsel lead welding pads and two hook-up wire welding pads provided on a top and a bottom surface thereof, respectively. The tinsel lead welding pads are located between the voice coil and the outgoing lead grooves, allowing the two tinsel leads to be separately welded thereto. With the above signal transmission structure for speaker, welding of tinsel leads and hook-up wires thereto can be conveniently performed to reduce labor and time costs.

Abstract: A signal transmission structure for speaker includes a base having two outgoing lead grooves provided on the same side thereof; a magnet member arranged on the base; a voice coil movably disposed over the magnet member; two tinsel leads respectively having an end connected to two opposite sides of the voice coil and another end set in the two outgoing lead grooves; and a signal connection board disposed in the base with two tinsel lead welding pads and two hook-up wire welding pads provided on a top and a bottom surface thereof, respectively. The tinsel lead welding pads are located between the voice coil and the outgoing lead grooves, allowing the two tinsel leads to be separately welded thereto. With the above signal transmission structure for speaker, welding of tinsel leads and hook-up wires thereto can be conveniently performed to reduce labor and time costs.

Abstract: A transmission and drive system comprises an input end connected to a driving device, an output end connected to a rear wheel, a gear transmission mechanism and a belt driven transmission mechanism. A unidirectional transmission mechanism is connected to the rear wheel with the unidirectional transmission mechanism driving the rear wheel. The transmission provides power output by the driving device, transmits power to the pulley transmission mechanism by the gear transmission mechanism, and the pulley transmission mechanism drives the rear wheel to rotate the unidirectional transmission mechanism, such that the vehicle moves forward. Noise dampening plates are provided to reduce noise emanating from the transmission. In addition, a belt tensioning system is provided to maintain consistent tension on the belt.

Abstract: The disclosure provides an intelligent water control equipment for intermittently countercurrent rinsing plating articles, comprising: a multi-stage countercurrent rinse tank, a PLC automatic control system, a liquid level sensor, a water supply pump, a water discharge pump, a water inlet pipe and a water output pipe; the multi-stage countercurrent rinse tank is composed of n rinse tanks connected in series, the water inlet pipe of a preceding-stage rinse tank is connected with the water outlet pipe of a next-stage rinse tank, rinse water is conveyed to the final-stage rinse tank through the water supply pump, the water flow direction is opposite to the movement direction of plating articles; signals of the liquid level sensor and a conductivity electrode are input to the PLC automatic control system.

Abstract: A transmission comprises an input end connected to a driving device, an output end connected to a rear wheel, a gear transmission mechanism and a pulley transmission mechanism. The gear transmission mechanism comprises a primary gear connected to the driving mechanism. The pulley transmission mechanism comprises a driving wheel, a driven wheel and a synchronous belt. A unidirectional transmission mechanism is connected to the driven wheel with the unidirectional transmission mechanism driving the rear wheel. The transmission provides power output by the driving device, transmits power to the pulley transmission mechanism by the gear transmission mechanism, and the pulley transmission mechanism drives the rear wheel to rotate the unidirectional transmission mechanism, such that the vehicle moves forward.

Abstract: An optical fiber detection method includes: selecting an optical fiber path required to be detected and setting relevant parameters of an optical fiber detection device related to the optical fiber path (S10); sending a detection starting instruction to the optical fiber detection device for the optical fiber detection device to detect the optical fiber path according to the detection starting instruction (S20); receiving a result of the detection performed by the optical fiber detection device on the optical fiber path, and analyzing the result of the detection to acquire the working status of the optical fiber path (S30). A network element management system and an optical fiber detection device and platform are also described.

Abstract: Compositions comprise a highly miscible polymer blend of at least one cellulose derivative and at least one polysiloxane additive of formula [R1R2R3SiO0.5]a[R4R5SiO]b[R6SiO1.5]c[SiO2]d, wherein the substituents R1, R2, R3, R4, R5 and R6 each independently represents a hydrocarbon group or a functional group selected from a hydroxyl group, an acyloxy group or an alkoxy group, and may be the same or different from each other with respect to each individual silicon atom, and 0?a?0.4, 0.01?b?0.99, 0.01?c?0.99, 0?d?0.3, under the proviso that at least one hydrocarbon group and at least one functional group are present and a+b+c+d=1.

Abstract: Disclosed is a conductive composition useful for the preparation of electrically conductive structures on a substrate comprising a plurality of metal particles, a plurality of glass particles and a vehicle comprising at least one cellulose derivative and at least one solid organopolysiloxane resin dissolved in a mutual organic solvent. The solid organopolysiloxane resin acts as adhesion promoter and assists in stably dispersing the metal and glass particles to avoid an agglomeration of such particles without degrading the rheological properties. From such conductive compositions uniform well adherent electrically conductive structures essentially free from defects in the form of cracks, bubbles or coarse particulates can be prepared on dielectric or semiconductor substrates such as silicon wafers in an efficient and cost-saving manner e.g. by screen printing, drying and sintering while inducing only low warping of the substrate.

Abstract: Compositions comprise a highly miscible polymer blend of at least one cellulose derivative and at least one polysiloxane additive of formula [R1R2R3SiO0.5]a[R4R5SiO]b[R6SiO1.5]c[SiO2]d, wherein the substituents R1, R2, R3, R4, R5 and R6 each independently represents a hydrocarbon group or a functional group selected from a hydroxyl group, an acyloxy group or an alkoxy group, and may be the same or different from each other with respect to each individual silicon atom, and 0?a?0.4, 0.01?b?0.99, 0.01?c?0.99, 0?d?0.3, under the proviso that at least one hydrocarbon group and at least one functional group are present and a+b+c+d=1.

Abstract: The present invention regards mutant forms of Bik that comprise anti-cell proliferation and/or pro-apoptotic activities. In particular embodiments, the Bik polypeptides comprise a substitution at Thr33 and Ser35 and, in some embodiments, phosphorylation at these sites is inhibited. In more particular embodiments, these forms are useful for cancer therapy, particularly when administered in combination with liposomes. In embodiments wherein a mutant Bik polynucleotide is administered for cancer therapy, the polynucleotide may be regulated in a tissue-specific manner.

Abstract: An absorptive device to carbon dioxide comprising a rotating packed bed includes a sealed housing, in which a filler is speedily rotated by a motor. A liquid distributor on the filler center communicates an absorbent entrance. An air pump impels the air into the housing; an absorbent reservoir saves an absorbent extruded from an absorbent exit; a water pump forces the absorbent within the absorbent reservoir into the housing. The absorbent flows through the liquid distributor into the filler center; the air enters the center through the filler. The absorbent spurts via the centrifugal force created by the super gravity field at a speedy rotation more than 100 G to meet the carbon dioxide in the air at the filler center, thence achieving a chemical absorption to absorb carbon dioxide, discharging redundant air from the air exit, and recycling the absorbent with the absorption of carbon dioxide in the absorbent reservoir.

Abstract: The present invention regards mutant forms of Bik that comprise anti-cell proliferation and/or pro-apoptotic activities. In particular embodiments, the Bik polypeptides comprise a substitution at Thr33 and Ser35 and, in some embodiments, phosphorylation at these sites is inhibited. In more particular embodiments, these forms are useful for cancer therapy, particularly when administered in combination with liposomes. In embodiments wherein a mutant Bik polynucleotide is administered for cancer therapy, the polynucleotide may be regulated in a tissue-specific manner.

Abstract: The present invention regards mutant forms of Bik that comprise anti-cell proliferation and/or pro-apoptotic activities. In particular embodiments, the Bik polypeptides comprise a substitution at Thr33 and Ser35 and, in some embodiments, phosphorylation at these sites is inhibited. In more particular embodiments, these forms are useful for cancer therapy, particularly when administered in combination with liposomes. In embodiments wherein a mutant Bik polynucleotide is administered for cancer therapy, the polynucleotide may be regulated in a tissue-specific manner.

Abstract: A camera having a housing, an imaging array positioned in said housing, and a lens assembly is disclosed. The lens assembly includes a fixed portion attached to the housing and a moveable portion connected to the fixed portion by a threaded coupling. The lens is positioned in the moveable portion to image a scene on the imaging array. The lens is separated from the imaging array by a distance that changes as the moveable portion is rotated relative to the fixed portion. The moveable portion includes a gear for applying a torque to the moveable portion such that the moveable portion moves relative to the fixed portion. The gear is preferably a spur gear. During the assembly of the camera, the gear is turned via a second gear such that the position of the lens is moved to a predetermined desired position.

Abstract: The present invention regards mutant forms of Bik that comprise anti-cell proliferation and/or pro-apoptotic activities. In particular embodiments, the Bik polypeptides comprise a substitution at Thr33 and Ser35 and, in some embodiments, phosphorylation at these sites is inhibited. In more particular embodiments, these forms are useful for cancer therapy, particularly when administered in combination with liposomes. In embodiments wherein a mutant Bik polynucleotide is administered for cancer therapy, the polynucleotide may be regulated in a tissue-specific manner.