Abstract: A pyridine derivative and use thereof are provided. The compound has an obvious inhibitory effect on the activity of KRAS and PI3K proteins, can be used as a KRAS and/or PI3K protein inhibitor, and can be used for preparing a drug for treatment of diseases such as KRAS or PI3K protein-mediated cancer. The compound has an extremely strong inhibitory effect on a KRAS G12C inhibitor (e.g. AMG-510) drug-resistant cancer cells, and has a wide application prospect thereof.

Abstract: An anti-oxidation dipping treatment method for a graphite sealing element for a thermal power generation unit, and an anti-oxidation production line. The anti-oxidation dipping treatment method for a graphite sealing element for a thermal power generation unit comprises the following steps: S1, placing a graphite sheet into a soaking device for soaking; S2, conveying the soaked graphite sheet into a drying and curing device for drying and curing; S3, stacking the multiple dried and cured graphite sheets together, and subjecting same to compression molding to form a layered graphite body; and S4, stamping the layered graphite body to form a finished graphite sealing element with a desired appearance.

Abstract: A method of evaluating an ability of a large language model (LLM) to generate an accurate hypothesis model (HM) of a linear programming word problem (LPWP) is provided. An attributed bipartite graph of the HM is transformed into an attributed bipartite graph of the ground truth model of the LPWP. The number of transformation steps required for the transformation effectively measures the ability of the LLM to generate an accurate HM. The use of attributed bipartite graphs provide invariance in the order to LPWP variables and constraints. Corresponding apparatus and systems are also provided.

Abstract: A lamp includes a cover plate, a housing, and a light source assembly. At least one side wall of the housing is a light-emitting surface; the cover plate and the housing are enclosed to form an accommodating space; the light source assembly is arranged in the accommodating space; and the light source assembly emits light toward the cover plate.

Abstract: A method for preparing a finerenone intermediate compound of formula I from a diastereomeric tartrate by means of racemic resolution is provided. A compound of formula I having an ee value higher than 99.5% can be obtained. The preparation method provided has mild reaction conditions, simple post-treatment, and no special reagents required, and is suitable for industrial production.

Abstract: The present invention provides a micro-light night vision lens comprising a hollow cylinder body; a number of transition segments, communicated with each other provided in turn on an inner surface of the cylinder body along its axial extension direction; a plurality of lens units, provided in succession and at intervals at different positions on the inner surface of the cylinder body along the central axis direction thereof; a CCD unit, provided at one end of the cylinder body in the axial direction and located on the light-out side of the lens unit therein, and spaced apart from the cylinder body, the radial dimension of the CCD unit does not exceed the diameter of the lens unit at the other end of the cylinder body in the axial direction. By reasonably laying out the lens unit, the present invention obtains a larger effective focal length and imaging quality.

Abstract: An iron-carbon composite material, a preparation method therefor, and an application thereof related to microbial technology applications. The method includes the following steps: a cross-linking and curing step: carrying out cross-linking and curing to iron powder and biological activated carbon by using an alkaline earth metal salt and a cross-linking agent; and a mineralization treatment step: soaking the cross-linked and cured iron-carbon composite material in a mineralization bacteria solution for 5-15 min, and carrying out drying to obtain an iron-carbon composite material.

Abstract: A solid dispersion, a preparation method therefor, and a solid formulation comprising same. The solid dispersion comprises compound A and a pharmaceutically acceptable matrix polymer, wherein the pharmaceutically acceptable matrix polymer includes an enteric high-molecular polymer and a non-enteric high-molecular polymer, and the compound A is 1-{(6-[(1-methyl)-4-pyrazolyl]-imidazo[1,2-a]pyridine)-3-sulfonyl}-6-[(1-methyl)-4-pyrazolyl]-1-hydro-pyrazolo[4,3-b]pyridine. The solid dispersion can significantly improve the solubility and dissolution stability of the compound A, prolong the supersaturation maintenance time of a drug, and further improve the bioavailability of the drug. The in vivo bioavailability of a solid formulation prepared from the solid dispersion meets the requirement of oral administration of the compound A.

Abstract: An integrated heat management system includes: a heat pump subsystem, configured to exchange heat with a passenger compartment and a battery of a vehicle; a high-pressure cooling subsystem, configured to exchange heat with a high-pressure system of the vehicle and the heat pump subsystem; a battery self-heating subsystem, configured to heat the battery through charging and discharging; an air heating subsystem, configured to exchange heat with the passenger compartment; the heat pump subsystem including a compressor and a control valve, one end of the control valve being in communication with an exhaust port of the compressor, and an other end of the control valve being in communication with an air return port of the compressor directly or through a gas-liquid separator; and a control subsystem, configured to control the control valve to be in communication with the exhaust port and the air return port of the compressor.

Abstract: An emulated card switching method, electronic device, and communication system are provided. The method includes sending first information to an near field communication (NFC) card reader which determines a first protocol based on the first information and a protocol supported by the NFC card reader, and performs a service process of the first protocol with the electronic device, if no identification information is obtained, modifying protocol information of a first emulated card from the first information to second information, sending the second information to the NFC card reader which obtains the second information from the electronic device, determines a second protocol based on the second information and the protocol supported by the NFC card reader, and performs a service process of the second protocol with the electronic device, and if identification information is obtained, switching the first emulated card to a second emulated card corresponding to the identification information.

Abstract: An energy conversion device is provided, including: a first electrical motor control circuit, where the first electrical motor control circuit is connected with a battery pack; a second electrical motor control circuit, where the second electrical motor control circuit is connected with the first electrical motor control circuit in parallel; and a controller, configured to: when operating in a first control mode, control the first electrical motor control circuit to charge and discharge the battery pack to heat the battery pack, and control the second electrical motor control circuit to output torque.

Abstract: An electronic cigarette control method, an electronic cigarette control device and an electronic cigarette using the control method and the control device are provided. The control method includes: determining the suction force indication information according to the information detected by a detecting assembly, wherein the detecting assembly includes a first air pressure detecting member arranged in an air passage in communication with a mouthpiece; determining the target value of a working parameter of an atomizer according to the suction force indication information, wherein the working parameter includes at least one of the output power, the temperature in an atomizing chamber, the working voltage of the atomizer, and the temperature of a heating member; and controlling the atomizer to work according to the target value of the working parameter. The control method can adjust the output power, so that the user can obtain different smoking tastes.

Abstract: The present disclosure provides a substrate, a maintenance method thereof and a display device. The substrate includes a base substrate, the base substrate is provided with at least one conductive pattern, and at least one of the at least one conductive pattern is interrupted and divided into a first conductive sub-pattern and a second conductive sub-pattern. The maintenance method includes: coating a conductive material in an interruption region in such a manner as to cover both the first conductive sub-pattern and the second conductive sub-pattern; and coating an organic insulation material at a side of the conductive material away from the base substrate, and curing the organic insulation material to form an organic protection film covering the conductive material.

Abstract: An emulated card switching method, electronic device, and communication system are provided. The method includes sending first information to an near field communication (NFC) card reader which determines a first protocol based on the first information and a protocol supported by the NFC card reader, and performs a service process of the first protocol with the electronic device, if no identification information is obtained, modifying protocol information of a first emulated card from the first information to second information, sending the second information to the NFC card reader which obtains the second information from the electronic device, determines a second protocol based on the second information and the protocol supported by the NFC card reader, and performs a service process of the second protocol with the electronic device, and if identification information is obtained, switching the first emulated card to a second emulated card corresponding to the identification information.

Abstract: A vehicle and a temperature control device thereof are disclosed. The temperature control device includes a motor control circuit and a heat exchange medium circulation loop. The motor control circuit includes a switch module, a three-phase inverter, a three-phase alternating current motor, and a control module. The heat exchange medium circulation loop includes a first valve electrically connected to the control module. At least one of the three-phase inverter and the three-phase alternating current motor and the first valve form an electrically driven cooling loop through a heat exchange medium pipeline. The first valve and a component to be heated form a cooling loop through a heat exchange medium pipeline.

Abstract: A vehicle battery thermal management system includes a heat conducting element connected to a vehicle air conditioning system and a self-heating circuit connected to a vehicle power battery. The heat conducting element, a compressor of the vehicle air conditioning system, and an outdoor condenser of the vehicle air conditioning system form a battery refrigeration loop, and the battery refrigeration loop absorbs heat from the vehicle power battery through a refrigerant in the heat conducting element to cool down the vehicle power battery. The self-heating circuit and the vehicle power battery form a battery self-heating loop, and the self-heating circuit is configured to control the vehicle power battery to perform high-frequency alternating charging and discharging for self-heating in the battery self-heating loop.

Abstract: A flyback converter is provided that detects a load-transient-produced increase in the output current to more quickly detect and respond to the load transient.

Abstract: The present disclosure discloses a method for capturing a trip sign of a turbine due to a high bearing temperature based on correlation and a device therefor. By combining a temperature of a target bearing and related operating parameters thereof, this method can capture possible abnormal trip online. According to the present disclosure, it is not necessary to add additional detection equipment, and it does not need to establish a complex physical model for turbine bearings, and only the historical data of the operating parameters of the temperature of the target bearing and generator set operating parameters related to the temperature of the target bearing are required to complete the establishment of the model for capturing abnormal sign before the trip, which is convenient for popularization and application.

Abstract: Embodiments of this application disclose an NFC-based communication method, an apparatus, and a system. In the NFC-based communication method, an electronic device works in an NFC reader/writer mode and performs an NFC communication process with an NFC tag. When failing to perform the NFC communication process, the electronic device may adjust a currently used radio frequency parameter, and re-perform the NFC communication process with the NFC tag by using an adjusted radio frequency parameter.

Abstract: The present disclosure belongs to the field of vehicles, and relates to a battery energy processing device and method and a vehicle, which can charge batteries during self-heating of the batteries. The battery energy processing device includes: an energy exchange interface; a first circuit, wherein a first end of the first circuit is connected with the energy exchange interface, and a second end of the first circuit is connected with a battery; a second circuit, wherein a first end of the second circuit is connected with the battery; an energy storage device, connected with a second end of the second circuit; and a controller, configured to: in a first preset state, control the second circuit to charge and discharge the battery to heat the battery, and control the first circuit to receive energy from the energy exchange interface and output the energy to the battery to charge the battery.