Abstract: The present disclosure provides a haptic rendering device, a method, a display device and a controller. The haptic rendering device includes: a substrate; a first driver arranged on the substrate and configured to vibrate and drive the substrate to vibrate after receiving a first driving signal; a vibration sensor arranged on the substrate and configured to generate a first detection voltage signal according to an amplitude or a frequency at which the first driver vibrates together with the substrate in a case where the substrate vibrates; and a controller configured to output the first driving signal to the first driver, receive the first detection voltage signal, and adjust the first driving signal according to the first detection voltage signal.

Abstract: Provided in the present invention are an improved hinge area and the use of same in constructing CAR skeleton. The amino acid sequence of the improved hinge area is as shown in SEQ ID NO.1 or SEQ ID NO.2 or SEQ ID NO.3, and the hinge area can prolong the survival of CAR-T cells in vivo and/or improve the capability of CAR-T cells to infiltrate tumors.

Abstract: A display panel includes an array substrate, a composite functional layer, a first adhesive layer and a cover plate. The composite functional layer is located on a side of the light-emitting layer away from the base substrate. A through hole penetrating through the composite functional layer and the array substrate is formed on the array substrate and the composite functional layer. The array substrate includes a non-display area surrounding the through hole. The composite functional layer includes a first shading layer, and the orthographic projection of the first shading layer on the array substrate is located in the non-display area of the array substrate. The first adhesive layer is located on a side of the composite functional layer away from the base substrate. The cover plate is located on a side of the first adhesive layer away from the base substrate.

Abstract: The present invention relates to processes of preparing PD-1/PD-L1 inhibitor (R)-1-((7-cyano-2-(3?-(3-(((R)-3-hydroxypyrrolidin-1-yl)methyl)-1,7-naphthyridin-8-ylamino)-2,2?-dimethylbiphenyl-3-yl)benzo[d]oxazol-5-yl)methyl)pyrrolidine-3-carboxylic acid, or salts thereof, related synthetic intermediates, and salts of the intermediates, where the PD-1/PD-L1 inhibitor is useful in the treatment of various diseases including infectious diseases and cancer.

Abstract: The present disclosure is related to processes for preparing baricitinib, salts thereof, and related synthetic intermediate compounds and salts thereof.

Abstract: A display panel includes an array substrate, a composite functional layer, a first adhesive layer and a cover plate. The composite functional layer is located on a side of the light-emitting layer away from the base substrate. A through hole penetrating through the composite functional layer and the array substrate is formed on the array substrate and the composite functional layer. The array substrate includes a non-display area surrounding the through hole. The composite functional layer includes a first shading layer, and the orthographic projection of the first shading layer on the array substrate is located in the non-display area of the array substrate. The first adhesive layer is located on a side of the composite functional layer away from the base substrate. The cover plate is located on a side of the first adhesive layer away from the base substrate.

Abstract: A profiling device, a profiling method, a bonding system, a bonding method, and a display device are provided. The profiling device includes a profiling jig. The profiling jig includes an attaching surface. The attaching surface is switchable between a planar state and a profiling state, and the attaching surface is a planar surface in the case that the attaching surface is in the planar state, and the attaching surface is a profiling surface in the case that the attaching surface is in the profiling state.

Abstract: The present disclosure is related to processes for preparing baricitinib, salts thereof, and related synthetic intermediate compounds and salts thereof.

Abstract: A haptic reproduction system comprises: a touch display device, an upper computer and a waveform generator. The touch display device comprises a piezoelectric unit, a touch display panel and a touch driving unit. The piezoelectric unit is disposed on the touch display panel. The touch driving unit is electrically connected to the touch display panel and the upper computer, and is configured to acquire touch information and transmit the touch information to the upper computer. The upper computer is electrically connected to the waveform generator, and is configured to send a first waveform generation instruction to the waveform generator according to the touch information. The waveform generator is configured to generate a first waveform signal according to the first waveform generation instruction. The piezoelectric unit is electrically connected to the waveform generator, and is configured to resonate with the touch display panel under the drive of the first waveform signal.

Abstract: A flexible display module includes a flexible display panel, a driving chip and a circuit board. The flexible display panel includes a display region and a bonding region arranged at a side of the display region opposite to a light-exiting side, and a bending region between the display region and the bonding region. The flexible display module further includes a flexible substrate supporting the flexible display panel, the flexible substrate includes a first flexible substrate and a second flexible substrate. The circuit board is connected to the other end of the second flexible substrate at a first position. An orthographic projection of the driving chip onto a plane where the first flexible substrate is located and an orthographic projection of the bending region onto the plane where the first flexible substrate is located are both located on a same side of a first vertical line.

Abstract: Disclosed is a virtual haptic assembly and a virtual haptic system. The virtual haptic assembly includes a display screen; an actuator on a light emitting side of the display screen, where the actuator includes a touch panel and a piezoelectric sensor, the touch panel includes a touch area and a non-touch area on at least one side of the touch area, the piezoelectric sensor is located on one side of the touch panel facing the display screen, and the piezoelectric sensor is configured to drive the touch panel to vibrate to form haptic feedback in response to interactive information of a user; and a first cushion, fixed between the display screen and the actuator, where an orthographic projection of the first cushion on the touch panel is located in the non-touch area.

Abstract: The present invention is related to processes for preparing itacitinib, or a salt thereof, and related synthetic intermediates related thereto.

Abstract: A display device is disclosed. The display device includes a module outer frame, including a display opening window, where an accommodation space is formed inside the module outer frame; a display module, fixed in the accommodating space, where a light emitting side of the display module faces the display opening window; a touch module, fixed between the display module and the display opening window, where the touch module includes a haptic sensor configured to generate a standing wave on a surface of the touch module during operation; a first isolation structure, arranged between the touch module and the module outer frame, where the first isolation structure is configured to isolate the touch module from the module outer frame; and a second isolation structure, arranged between the display module and the touch module, where the second isolation structure is configured to isolate the display module from the touch module.

Abstract: A two-component adhesive composition comprising the reaction product of: a polyol component, comprising a hydrophobic polyol and a phosphate-functional adhesion promoter; and an isocyanate component, comprising the reaction product of an isocyanate monomer and a dimer acid polyester polyol.

Abstract: A polyurethane composition reaction mixture including: (a) at least one organic isocyanate; and (b) at least one butylene oxide-based hydrophobic polyol; a process for making the above polyurethane composition; a polyurethane composite article composition, a process for making the above polyurethane composite article composition; and a process for making a composite article from the above polyurethane composite article composition.

Abstract: A seed coating composition includes a silane-functionalized polymer. The silane-functionalized polymer is acrylate-based. The seed coating composition also includes polydimethylsiloxane having a weight average molecular weight of 500,000 g/mol or greater as measured according to Gel Permeation Chromatography.

Abstract: Described is a curable composition, and particularly a two-component composition comprising a silane modified polymer; an epoxy resin terminated with epoxy terminal group; wherein the composition further comprises a hardening agent and a compatibilizer which has at least one silane group and at least one epoxy terminal group. The curable composition exhibits enhanced adhesion strength and good elongation at break. A method for applying the curable composition on the surface of a substrate is also provided.

Abstract: Described is a curable composition, and particularly a two-component composition comprising a silane modified polymer; an epoxy resin terminated with epoxy terminal group; wherein the composition further comprises a hardening-compatibilizing agent which has at least one silane group and at least two amine groups. The curable composition exhibits enhanced adhesion strength and good elongation at break. A method for applying the curable composition on the surface of a substrate is also provided.

Abstract: Described is a curable composition comprising a silane modified polymer; an epoxy resin terminated with epoxy terminal group; a compatibilizer having at least one silane group and at least one epoxy terminal group or at least one nitrogen-containing groups; and optionally a hardening agent; wherein the composition further optionally comprises at least one of a nitrogen-containing unsaturated heterocyclic compound catalyst and a nitrogen-containing phenol catalyst. The curable composition exhibits high hermeticity, fast curing speed, quick adhesion build up, dry surface and strong adhesion strength. A method for applying the curable composition on the surface of a substrate is also provided.

Abstract: A polyurethane composition reaction mixture including: (a) at least one organic isocyanate; and (b) at least one butylene oxide-based hydrophobic polyol; a process for making the above polyurethane composition; a polyurethane composite article composition, a process for making the above polyurethane composite article composition; and a process for making a composite article from the above polyurethane composite article composition.