Patents by Inventor Yongfen Ma

Yongfen Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Difluoro phenyl amide RIP1 inhibitor
    Patent number: 12129221
    Abstract: The disclosed compounds inhibit cellular necrosis, and include corresponding sulfonamides, prodrugs and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: October 29, 2024
    Assignee: SIRONAX LTD
    Inventors: Zhiyuan Zhang, Yaning Su, Yi Yang, Guozheng Wang, Wendong Liu, Yongfen Ma, Yan Ren
  • RIP1 Inhibitors
    Publication number: 20210284598
    Abstract: The invention provides amides that inhibit cellular necrosis including corresponding sulfonamides, prodrugs and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
    Type: Application
    Filed: May 19, 2021
    Publication date: September 16, 2021
    Applicant: SIRONAX LTD
    Inventors: Zhiyuan Zhang, Yaning Su, Yi Yang, Guozheng Wang, Wendong Liu, Yongfen Ma, Yan Ren