Abstract: The present disclosure relates to a robot, and provides a 3 degree-of-freedom parallel mechanism with 3 branched-chains, which includes a fixed platform, a movable platform, and three arc-shaped connecting rods. The rotation axes of three arc-shaped connecting rods are intersected with each other and each rotation axes is parallel to the fixed platform. Each arc-shaped connecting rod has a sliding slot curved extending along a longitudinal direction. The three connecting shafts one-to-one corresponds to the three arc-shaped connecting rods and are disposed on the movable platform. A first end of each connecting shaft is fixedly connected with the movable platform. A second end is hinged joint with a connecting head. The connecting head is slid and disposed in the corresponding sliding slot.

Abstract: The disclosure relates to a surgical instrument and discloses a flexible drive member, an end-effector, and a surgical instrument. The flexible drive member includes a distal portion, a proximal portion, and a bendable portion therebetween, wherein the bendable portion includes a plurality of wire bundles extending in the length direction of the flexible drive member, and a flexible casing enclosing the plurality of wire bundles. In the technical solutions of the disclosure, the bendable portion is provided with some rigidity and flexibility due to the plurality of wire bundles, and the flexibly casing can fix the plurality of wire bundles relatively and can alleviate friction rate of the surface of the flexible drive member and further improve the rigidity of the flexible drive member.

Abstract: A device for continuously generating high intensity neutrons is provided. The device includes a differential vacuum system, a throttle pipe, a linear target tube and a solid target device arranged in sequence along a moving direction of a beam. The beam and a gaseous medium react in the linear target tube, and the beam and a solid medium react in the solid target device. Two ends of an inner cavity of the linear target tube are hermetically connected to the throttle pipe and a chamber of the solid target device, respectively.

Abstract: Disclosed are an articulating assembly and a surgical instrument using the same. The articulating assembly includes a driver assembly configured to articulate an end effector of said surgical instrument, where said driver assembly includes: a screw portion rotatably mounted in a stationary handle of said surgical instrument, an axis of which is parallel to an axis of an elongated portion of said surgical instrument, wherein said screw portion is provided with at least two segments with opposite threads; two articulation plates in connection with said two thread segments, respectively, wherein a distal end of each articulation plate is in connection with said end effector of said surgical instrument; and a rotating sleeve coaxially sheathed on said screw portion so as to be in connection therewith through a gear assembly when being located at an articulation position.

Abstract: Methods and devices for email management are provided. According to email information of emails in an email box, whether an email box contains advertisement emails is determined. The email information at least contains sender addresses of the emails. When the email box contains the advertisement emails, classification data of the advertisement emails are obtained by obtaining the email information of the advertisement emails and classifying the advertisement emails, according to the sender addresses thereof, to form advertisement-email sets with each set containing at least one advertisement email. The at least one advertisement email in a same advertisement-email set has a same sender address. The advertisement emails are displayed according to the classification data thereof. Accordingly, the email managing device includes a determining module, an obtaining module, and a displaying module.

Abstract: The present invention provides taxanes compounds with a formula (I) or formula (II) structure, a method for preparing the compounds, as well as the use of the compositions containing the compounds, pharmaceutically acceptable salts and solvates thereof as active ingredients in manufacturing oral antitumor medicaments, In formula (I), R1 is —COR6, —COOR6 or —CONR7aR7b; R2 is a C1-C6 alkyl, a C1-C6 alkenyl, a substituted hydrocarbon group, a heterocyclic group, an aromatic group or a substituted aromatic group; R3 is —OR6, —OCOOR6, —OCOSR6 or —OCONR7aR7b; R4 is —OR6, —OCOOR6, —OCOSR6, —OCONR7aR7b or H; wherein, R6 is a C1-C6 alkyl, a C1-C6 alkenyl, a C1-C6 alkynyl, a substituted hydrocarbon group, an aromatic group or a heterocyclic group; R7a and R7b are respectively hydrogen, a hydrocarbon group, a substituted hydrocarbon group or a heterocyclic group.

Abstract: A suturing nail includes a first nail body a second nail body being intertwined mutually to form a helix portion; a first nail crown extending from an end of the first nail body; a second nail crown extending from an end of the second nail body and opposite to the first nail crown, the first and the second nail crown being located on the same side of the helix portion and perpendicular to the helix portion; a first nail leg extending from the other end of the first nail body; a second nail leg extending from the other end of the second nail body and being spaced from the first nail, the first and the second nail leg are located on the same side of the helix portion, the first nail leg and the second nail leg are parallel to the helix portion.

Abstract: Provided are taxanes compounds having the structure of formula I, preparation method thereof, and uses of compositions having the compound, pharmaceutical salts and solvates thereof as active ingredients in the preparation of oral antitumor drugs. In the formula, R1 is —COR6, —COOR6, and —CONR7aR7b; R2 is C1-C6 alkyl, C1-C6 alkenyl group, a substituted hydrocarbon group, a heterocyclic group, an aromatic group or a substituted aromatic group; R3 is —OR6, —OCOOR6, —OCOSR6, and —OCONR7aR7b; R4 is —OR6, —OCOOR6, —OCOSR6, —OCONR7aR7b, H, and OH; R6 is C1-C6 alkyl, C1-C6 alkenyl, C1-C6 alkynyl group, a substituted hydrocarbon group, an aromatic group or a heterocyclic group; and R7a and R7b are respectively hydrogen, a hydrocarbon group, a substituted hydrocarbon group or a heterocyclic group.

Abstract: The present application discloses an A-type polymorphic substance of yonkenafil hydrochloride and a preparation method, a composition and use thereof. The powder diffraction pattern of the A-type polymorphic substance of yonkenafil hydrochloride comprises diffraction peaks at three or more 2? values selected from: 8.4±0.2°, 11.3±0.2°, 13.9±0.2°, 14.2±0.2°, 14.7±0.2°, 16.8±0.2°, 17.1±0.2°, 19.7±0.2°, 21.0±0.2°, 21.7±0.2°, 22.4±0.2°, 23.3±0.2°, 23.8±0.2°, 26.8±0.2°, 27.5±0.2°, 28.0±0.2°.

Abstract: The present application discloses an A-type polymorphic substance of yonkenafil hydrochloride and a preparation method, a composition and use thereof. The powder diffraction pattern of the A-type polymorphic substance of yonkenafil hydrochloride comprises diffraction peaks at three or more 2? values selected from: 8.4±0.2°, 11.3±0.2°, 13.9±0.2°, 14.2±0.2°, 14.7±0.2°, 16.8±0.2°, 17.1±0.2°, 19.7±0.2°, 21.0±0.2°, 21.7±0.2°, 22.4±0.2°, 23.3±0.2°, 23.8±0.2°, 26.8±0.2°, 27.5±0.2°, 28.0±0.2°.

Abstract: A suturing nail includes a first nail body a second nail body being intertwined mutually to form a helix portion; a first nail crown extending from an end of the first nail body; a second nail crown extending from an end of the second nail body and opposite to the first nail crown, the first and the second nail crown being located on the same side of the helix portion and perpendicular to the helix portion; a first nail leg extending from the other end of the first nail body; a second nail leg extending from the other end of the second nail body and being spaced from the first nail, the first and the second nail leg are located on the same side of the helix portion, the first nail leg and the second nail leg are parallel to the helix portion. The suturing nail is not deformed easily.

Abstract: Disclosed are an articulating assembly and a surgical instrument using the same. The articulating assembly includes a driver assembly configured to articulate an end effector of said surgical instrument, where said driver assembly includes: a screw portion rotatably mounted in a stationary handle of said surgical instrument, an axis of which is parallel to an axis of an elongated portion of said surgical instrument, wherein said screw portion is provided with at least two segments with opposite threads; two articulation plates in connection with said two thread segments, respectively, wherein a distal end of each articulation plate is in connection with said end effector of said surgical instrument; and a rotating sleeve coaxially sheathed on said screw portion so as to be in connection therewith through a gear assembly when being located at an articulation position.

Abstract: A suturing nail includes a first nail body a second nail body being intertwined mutually to form a helix portion; a first nail crown extending from an end of the first nail body; a second nail crown extending from an end of the second nail body and opposite to the first nail crown, the first and the second nail crown being located on the same side of the helix portion and perpendicular to the helix portion; a first nail leg extending from the other end of the first nail body; a second nail leg extending from the other end of the second nail body and being spaced from the first nail, the first and the second nail leg are located on the same side of the helix portion, the first nail leg and the second nail leg are parallel to the helix portion.

Abstract: Methods and devices for email management are provided. According to email information of emails in an email box, whether an email box contains advertisement emails is determined. The email information at least contains sender addresses of the emails. When the email box contains the advertisement emails, classification data of the advertisement emails are obtained by obtaining the email information of the advertisement emails and classifying the advertisement emails, according to the sender addresses thereof, to form advertisement-email sets with each set containing at least one advertisement email. The at least one advertisement email in a same advertisement-email set has a same sender address. The advertisement emails are displayed according to the classification data thereof. Accordingly, the email managing device includes a determining module, an obtaining module, and a displaying module.

Abstract: Provided are taxanes compounds having the structure of formula I, preparation method thereof, and uses of compositions having the compound, pharmaceutical salts and solvates thereof as active ingredients in the preparation of oral antitumor drugs. In the formula, R1 is —COR6, —COOR6, and —CONR7aR7b; R2 is C1-C6 alkyl, C1-C6 alkenyl group, a substituted hydrocarbon group, a heterocyclic group, an aromatic group or a substituted aromatic group; R3 is —OR6, —OCOOR6, —OCOSR6, and —OCONR7aR7b; R4 is —OR6, —OCOOR6, —OCOSR6, —OCONR7aR7b, H, and OH; R6 is C1-C6 alkyl, C1-C6 alkenyl, C1-C6 alkynyl group, a substituted hydrocarbon group, an aromatic group or a heterocyclic group; and R7a and R7b are respectively hydrogen, a hydrocarbon group, a substituted hydrocarbon group or a heterocyclic group.

Abstract: The present invention provides taxanes compounds with a formula (I) or formula (II) structure, a method for preparing the compounds, as well as the use of the compositions containing the compounds, pharmaceutically acceptable salts and solvates thereof as active ingredients in manufacturing oral antitumor medicaments, In formula (I), R1 is —COR6, —COOR6 or —CONR7aR7b; R2 is a C1-C6 alkyl, a C1-C6 alkenyl, a substituted hydrocarbon group, a heterocyclic group, an aromatic group or a substituted aromatic group; R3 is —OR6, —OCOOR6, —OCOSR6 or —OCONR7aR7b; R4 is —OR6, —OCOOR6, —OCOSR6, —OCONR7aR7b or H; wherein, R6 is a C1-C6 alkyl, a C1-C6 alkenyl, a C1-C6 alkynyl, a substituted hydrocarbon group, an aromatic group or a heterocyclic group; R7a and R7b are respectively hydrogen, a hydrocarbon group, a substituted hydrocarbon group or a heterocyclic group.

Abstract: The disclosure relates to a surgical instrument and discloses a flexible drive member, an end-effector, and a surgical instrument. The flexible drive member includes a distal portion, a proximal portion, and a bendable portion therebetween, wherein the bendable portion includes a plurality of wire bundles extending in the length direction of the flexible drive member, and a flexible casing enclosing the plurality of wire bundles. In the technical solutions of the disclosure, the bendable portion is provided with some rigidity and flexibility due to the plurality of wire bundles, and the flexibly casing can fix the plurality of wire bundles relatively and can alleviate friction rate of the surface of the flexible drive member and further improve the rigidity of the flexible drive member.

Abstract: A suturing nail includes a first nail body a second nail body being intertwined mutually to form a helix portion; a first nail crown extending from an end of the first nail body; a second nail crown extending from an end of the second nail body and opposite to the first nail crown, the first and the second nail crown being located on the same side of the helix portion and perpendicular to the helix portion; a first nail leg extending from the other end of the first nail body; a second nail leg extending from the other end of the second nail body and being spaced from the first nail, the first and the second nail leg are located on the same side of the helix portion, the first nail leg and the second nail leg are parallel to the helix portion. The suturing nail is not deformed easily.

Abstract: The present invention relates to a controlled release system, in particular to a controlled release system containing temozolomide.

Abstract: The invention relates to the compounds of formula I, their preparation and the pharmaceutical compositions containing the compounds. The invention also relates to the use of the compounds of formula I in preparing medicines, which can treat sexual dysfunction of animals including human (male and female), especially erectile dysfunction of male and the diseases in which the function of phospholipase 5 (cGMP PDE5) is involved.