Abstract: Compositions for specifically cleaving target sequences in retroviruses include nucleic acids encoding a Clustered Regularly Interspace Short Palindromic Repeat (CRISPR) associated endonuclease and a guide RNA sequence complementary to one or more target nucleic acid sequences in a retrovirus genome.

Abstract: A single-layer shock-absorbing sports helmet formed by steam, including a hard shell and an EPP layer. The hard shell is fitted and bonded with the EPP layer by glue, and the hard layer covers an outer surface of the EPP layer. The EPP layer is made of an EPP material which is waterproof and heat resisting and insulating, such that the wearing comfort of the helmet is effectively improved. The hard shell and the EPP layer are bonded by glue, so less materials are used, thus the weight and cost will be reduced without affecting the use of the helmet. In addition, the helmet also has excellent impact resistance.

Abstract: The present invention provides electronic systems, including device arrays, comprising functional device(s) and/or device component(s) at least partially enclosed via one or more containment chambers, such that the device(s) and/or device component(s) are at least partially, and optionally entirely, immersed in a containment fluid. Useful containment fluids for use in containment chambers of electronic devices of the invention include lubricants, electrolytes and/or electronically resistive fluids. In some embodiments, for example, electronic systems of the invention comprise one or more electronic devices and/or device components provided in free-standing and/or tethered configurations that decouple forces originating upon deformation, stretching or compression of a supporting substrate from the free standing or tethered device or device component.

Abstract: The present invention discloses a system for measuring the mechanical properties of sea floor sediments at full ocean depth.

Abstract: A method of resolving a racemic mixture of (±)-Huperzine A to (?)-Huperzine A includes: separating the (?)-Huperzine A from the racemic mixture of (±)-Huperzine A by chiral high performance liquid chromatography (HPLC), the chiral HPLC being performed utilizing a mobile phase including a solution including an alcohol and one selected from dichloromethane, trichloromethane, and a mixture thereof, and the chiral HPLC being performed utilizing a chiral stationary phase including a polysaccharide derivative.

Abstract: The present invention relates to the field of fluid heat transfer, and discloses a heat transfer enhancement pipe as well as a cracking furnace and an atmospheric and vacuum heating furnace including the same. The heat transfer enhancement pipe (1) includes a pipe body (10) of tubular shape having an inlet (100) for entering of a fluid and an outlet (101) for said fluid to flow out; internal wall of the pipe body (10) is provided with a fin (11) protruding towards interior of the pipe body (10), the fin (11) spirally extends in an axial direction of the pipe body (10), wherein a height of the fin (11) gradually increases from one end in at least a part extension of the fin. The heat transfer enhancement pipe can reduce thermal stress of itself, thereby increasing service life of the heat transfer enhancement pipe.

Abstract: Disclosed is a preparation method for a racemic adrenaline as represented by formula II. The method comprises the following steps: compound 1 is directly racemized in an acidic solution to produce compound 2, the acid solution comprising neither sodium bisulfite nor salicylic acid; and specifically comprises (a), in the acid solution of which the pH is 0.5-1.5, compound 1 is placed under the protection of nitrogen gas and, with the reaction temperature being controlled at 75-95° C., stirred and reacted for 1-3 hours; (b) the reaction solution is controlled at a temperature of 5-20° C., into which an activated carbon is added, under the protection of nitrogen gas, stirred for 20-40 minutes, and filtered, then a filtrate is collected; the filtrate is controlled at a temperature of 5-20° C., the pH thereof is adjusted using ammonia to 8.5-9.5, and is filtered when the pH is stabilized, and a filter cake is washed and dried to produce a high purity racemic adrenaline white powder.

Abstract: A die assembly is disclosed. The die assembly includes a die, one or more die pads on a first surface of the die and a die attach film on the die where the die attach film includes one or more openings that expose the one or more die pads and that extend to one or more edges of the die.

Abstract: The present invention discloses a second-generation in-situ test device for strength of a shallow water sediment, including a workboat and a static cone penetration test unit carried by the workboat, where the static cone penetration unit includes a mounting frame, a penetration unit, a control cabin and a hydraulic unit; the penetration unit and the hydraulic unit are both electrically connected to the control cabin. In this solution, the workboat is used to carry the test equipment, and the static cone penetration test unit is carried on the workboat with a special structure. Based on a double-cable lifting frame, the equipment is launched and recovered through a moon pool in the center of a hull. This significantly improves the efficiency and safety of the sediment strength test operation in a shallow water environment.

Abstract: A preparation method for a racemic adrenaline as represented by formula II. The method may comprise the following steps: compound 1 is directly racemized in an acidic solution to produce compound 2, the acid solution comprising neither sodium bisulfite nor salicylic acid; and specifically comprises (a), in the acid solution of which the pH is 0.5-1.5, compound 1 is placed under the protection of nitrogen gas and, with the reaction temperature being controlled at 75-95° C., stirred and reacted for 1-3 hours; (b) the reaction solution is controlled at a temperature of 5-20° C., into which an activated carbon is added, under the protection of nitrogen gas, stirred for 20-40 minutes, and filtered, then a filtrate is collected; the filtrate is controlled at a temperature of 5-20° C., the pH thereof is adjusted using ammonia to 8.5-9.5, and is filtered when the pH is stabilized, and a filter cake is washed and dried to produce a high purity racemic adrenaline white powder.

Abstract: Compounds serving as histone deacetylase 6 (HDAC6) selective inhibitors, and applications thereof in the preparation of drugs for treating HDAC6-related diseases. Specifically disclosed are a compound as represented by formula (I) and a pharmaceutically acceptable salt thereof.

Abstract: Embodiments of wet processing systems and methods for uniform wet processing are disclosed. A method described in the present disclosure includes measuring one or more wafer characteristics of a wafer using a plurality of detectors and determining a wafer profile of the wafer based on the measured one or more wafer characteristics. The method also includes setting first and second sets of wet processing parameters of a wet processing system for respective first and second wafer regions based on the wafer profile, where a value of at least one wet processing parameter is different between the first and second sets of wet processing parameters. The method further includes performing wet processing on the wafer by dispensing one or more chemicals onto the first and second wafer regions according to the respective first and second sets of wet processing parameters.

Abstract: Network transformer structures including a production method therefore are disclosed. In one embodiment, multiple integrated I-shaped magnetic cores that include three winding barrel portions based on a new design for a magnetic core structure is disclosed. A first winding barrel portion and a second winding barrel portion are configured to wind a transformer winding, and a third winding barrel portion is configured to wind a common mode choke winding, so that a transformer and a common mode choke are combined onto one magnetic core to replace two previous magnetic cores, thereby saving on the overall network transformer structure cost as well as space on, for example, an end consumer printed circuit board.

Abstract: The invention provides a peptide amide compound represented by the general general formula (I), a preparation method thereof, and a medical application thereof. The compound has a novel structure, better biological activity, and better analgesic effect.

Abstract: An observation system and determination method for the re-suspension quantity of submarine sediments by deep-sea internal waves. The observation system comprises a submarine observation platform, a mooring rope, and an anchor mooring counterweight. Acoustic release transponder, a single-point current meter, a turbidity meter, a high-precision temperature and salinity detector, and a sediment catcher are mounted on the submarine observation platform. A main floating body and auxiliary floating bodies are arranged on the mooring rope, wherein the main floating body is located in the middle of the mooring rope and is equipped with acoustic Doppler current profilers, and the auxiliary floating bodies are equipped with turbidity meters and high-precision temperature and salinity detectors. The anchor mooring counterweight is a gravity anchor provided with a square clamping groove and a fixed ring.

Abstract: An observation system and determination method for the re-suspension quantity of submarine sediments by deep-sea internal waves. The observation system comprises a submarine observation platform, a mooring rope, and an anchor mooring counterweight. Acoustic release transponder, a single-point current meter, a turbidity meter, a high-precision temperature and salinity detector, and a sediment catcher are mounted on the submarine observation platform. A main floating body and auxiliary floating bodies are arranged on the mooring rope, wherein the main floating body is located in the middle of the mooring rope and is equipped with acoustic Doppler current profilers, and the auxiliary floating bodies are equipped with turbidity meters and high-precision temperature and salinity detectors. The anchor mooring counterweight is a gravity anchor provided with a square clamping groove and a fixed ring.

Abstract: A magnetic core of an electric motor includes a central portion and a plurality of teeth extending outwardly from the central portion, the teeth disposed along a circumferential direction of the central portion. Each tooth includes a tooth body, two neck portions and two crown portions, the neck portions respectively connecting the crown portions to the tooth body, the two crown portions respectively extending beyond opposite sides of the tooth body. Each of the two neck portions of each tooth has a minimum width which is 0.1˜0.3 times of the width of the tooth body. The present invention further provides an electric motor that employs the magnetic core which can increase the peak value of the cogging torque of the motor.

Abstract: A system for multi-layer quality of service (QoS) management in a distributed computing environment includes a management node hosting a workload scheduler operable to receive a workload and identify a workload QoS class for the workload. The system also includes a plurality of distributed compute nodes. A workload scheduler schedules running of the workload on the compute nodes, translates the workload QoS class to a storage level QoS class, and communicates the storage level QoS class to a workload execution manager of the compute nodes. The workload scheduler communicates the storage level QoS class to one or more storage managers where the storage managers manage storage resources, and the storage managers are operable to extend the storage level QoS class to the storage resources to support the workload QoS class.

Abstract: A technique for multi-layer quality of service (QoS) management in a distributed computing environment includes receiving a workload to run in a distributed computing environment. A workload quality of service (QoS) class for the workload is identified, and the workload QoS class is translated to a storage level QoS class. The workload is scheduled to run on a compute node of the environment, and the storage level QoS class is communicated to a workload execution manager of the compute node. The storage level QoS class is communicated to one or more storage managers of the environment where the storage managers manage storage resources in the environment. The storage managers extend the storage level QoS class to the storage resources to support the workload QoS class.

Abstract: A method for multi-layer quality of service (QoS) management in a distributed computing environment includes receiving a workload and identifying a workload QoS class for the workload. The workload is scheduled to be run compute nodes. The workload QoS class is translated to a plurality of different resource layer QoS classes, and the plurality of QoS classes are communicated to a workload execution manager of the compute nodes. The workload execution manager extends the plurality of different resource layer QoS classes to respective resource layers involved in the running of the workload.