Abstract: A bidirectional self-regulating chemical flooding method and system for enhancing oil recovery includes: determining the average particle size of dispersed phase droplets under stable seepage flow of an oil-in-water emulsion according to the average reservoir permeability; determining injection concentration of an emulsifier which matches a target reservoir according to reservoir seepage velocity; under a condition of keeping the injection concentration of the emulsifier constant, determining the optimal injection concentration of a polymer which matches the injection concentration of the emulsifier through core flooding experiments with the maximum equivalent ton oil accumulation as a target; determining total injection amount of the emulsifier and total injection amount of the polymer for implementing well group units; and optimizing injection amount of the emulsifier and the polymer in each single well by using a numerical simulator of a chemical flooding reservoir.

Abstract: An encapsulated polymer flooding method and system for enhancing oil recovery includes: (1) determining reservoir parameters, a well deployment, and a development dynamic state of a target oil reservoir; (2) determining a near-wellbore targeted profile control area and a far-wellbore targeted viscosification area; (3) designing and synthesizing an encapsulated polymer according to conditions of the target oil reservoir; (4) evaluating and determining whether the anti-shearing performance, the sustained release and viscosification performance, the injection performance, and the profile control performance of the encapsulated polymer meet expected performance requirements based on laboratory tests; (5) formulating an injection scheme for an encapsulated polymer flooding field; and (6) monitoring the development dynamic state of the oil reservoir; according to the present disclosure, the polymer is wrapped with a shell layer, which greatly reduces the shear degradation during injection of the polymer and effecti

Abstract: A method for realizing balanced displacement of crude oil by injection and production optimization coordinated chemical flooding which comprises the following steps: determining the median size and elastic modulus of viscoelastic particles according to the average permeability of the reservoir; optimizing the concentration ratio of the total concentration of the chemical agent; the physical parameters of each layer are counted, and the hierarchical system is combined according to the entropy weight algorithm and the cluster analysis method based on the gravity center method; the optimal section slug volume ratio of the single well injected with two slugs under the heterogeneity of the permeability of the strata is calculated; and the objective function is established by combining the coefficient of variation of remaining oil saturation, the effect of chemical flooding and the cost, and the numerical simulator is used to optimize the objective function.

Abstract: The application relates to the technical field of oil and gas field development, and discloses a correction method and system for a permeability model considering gas hydrate distribution, and a method and system for determining the permeability of the hydrate-bearing porous medium.

Abstract: A method for improving the gas recovery of a natural gas hydrate reservoir by using artificial impermeable layers is described. Artificial impermeable layers are formed by injecting cement slurry into the permeable overburden and underburden layers. When depressurization exploitation is performed, a large amount of seawater can be effectively blocked from entering a hydrate layer, and a production pressure difference between the hydrate layer and the production well is effectively increased, so that a hydrate decomposition rate and the gas recovery are improved.

Abstract: The disclosure discloses a method for obtaining formation parameters of a gas hydrate reservoir through well testing interpretation, which comprises: (1) establishing a physical model for well testing interpretation of the gas hydrate reservoir according to multiphase flow, hydrate dissociation, secondary hydrate formation and heat transfer exhibited in the well testing process of the gas hydrate reservoir; (2) establishing a mathematical model for well testing interpretation of the gas hydrate reservoir; (3) conducting spatial discretization and temporal discretization on the mathematical model, and adopting a finite volume method to obtain a numerical solution of bottom-hole pressure; (4) calculating a bottom-hole pressure variation curve and a production rate variation curve in the well testing process of the hydrate reservoir, and drawing theoretical curves of bottom-hole pressure difference and pressure difference derivative; and (5) matching a measured pressure curve with the theoretical curve to obtain

Abstract: A daily gas production rate of a methane hydrate deposit is calculated based on inflow performance relationship formulas. Step 1 determines the production stage, including the gas production rate trend of a production test and selecting an inflow performance relationship formula corresponding to the stage. Step 2 calculates basic coefficient terms related to energy conversion in the inflow performance relationship formula. Step 3 obtains other coefficient terms related to production in the inflow performance relationship formula. Step 4 predicts the gas production rate under other production pressure differences. Staged inflow performance relationship formulas characterize the complex methane hydrate deposit production performance.

Abstract: Disclosed is a method for simulation of a microscopic flow of pre-crosslinked gel suspension liquid in a porous medium, including the steps of: establishing a simulation area of the porous medium based on a two-dimensional core CT slice image and subjecting the simulation area to numerical grid discretization; setting initial position and original shape of pre-crosslinked gel particles to generate virtual boundary mark points; marking the type of numeric grid nodes; calculating the force of the fluid on each virtual boundary mark point according to the momentum change of the numerical grid nodes on the boundary of the pre-crosslinked gel particles; calculating the contact force on each virtual boundary mark point using a particle contact action model; calculating the bending recovery force and the stretching recovery force for each virtual boundary mark point based on the current shape and original shape of the pre-crosslinked gel particles; and calculating the velocity and displacement of each virtual bounda

Abstract: The example of implementation of the invention provides a method used for exploiting a natural gas hydrate reservoir and belongs to the field of natural gas hydrate reservoir exploitation. The method mainly comprises a heat-injecting vertical well and a production horizontal well. The production horizontal well is opened in a segmental manner. In combination with natural gas hydrate heat exploitation, heat flow injected into the vertical well is enabled to heat different positions of the natural gas hydrate reservoir to increase a recovery ratio of the natural gas hydrate reservoir. The method specifically comprises the steps of injecting a heat flow into the natural gas hydrate reservoir by utilizing the vertical well to promote decomposition of the hydrate; firstly opening a horizontal branch of the horizontal well fully and keeping depressurization exploitation.

Abstract: Disclosed is a method for simulation of a microscopic flow of pre-crosslinked gel suspension liquid in a porous medium, including the steps of: establishing a simulation area of the porous medium based on a two-dimensional core CT slice image and subjecting the simulation area to numerical grid discretization; setting initial position and original shape of pre-crosslinked gel particles to generate virtual boundary mark points; marking the type of numeric grid nodes; calculating the force of the fluid on each virtual boundary mark point according to the momentum change of the numerical grid nodes on the boundary of the pre-crosslinked gel particles; calculating the contact force on each virtual boundary mark point using a particle contact action model; calculating the bending recovery force and the stretching recovery force for each virtual boundary mark point based on the current shape and original shape of the pre-crosslinked gel particles; and calculating the velocity and displacement of each virtual bounda

Abstract: The present invention relates to methods of reducing cardiotoxicity and/or improving survival from treatment with anthracycline agents comprising administering a therapeutically effective amount of a composition comprising a vasopressin antagonist compound or a pharmaceutically acceptable salt thereof as an active ingredient, administered simultaneously or prior to the anthracycline administration.

Abstract: The present invention describes a method for reducing reperfusion injury and/or infarction by using an inhibitor of platelet GPVI. This method may be used to treat patients during or after a heart attack or elective cardiac surgery.

Abstract: The present invention relates to methods of reducing cardiotoxicity and/or improving survival from treatment with anthracycline agents comprising administering a therapeutically effective amount of a composition comprising a vasopressin antagonist compound or a pharmaceutically acceptable salt thereof as an active ingredient, administered simultaneously or prior to the anthracycline administration.

Abstract: The present invention relates to pharmaceutical compositions comprising at least one multifunctional phosphodiesterase inhibitor (MPDEI) and at least one adenosine uptake inhibitor. The present invention also relates to compositions comprising cilostazol and dipyridamole and their use.

Abstract: The present invention relates to a method for reducing infarction comprising administering to a patient ion need thereof a therapeutically effective amount of a composition comprising as an active ingredient a vasopressin antagonist compound and to a composition useful therefor. The present invention also relates to a method for reducing infarction comprising administering to a patient in need thereof a therapeutically effective amount of a combination of a vasopressin antagonist compound and a beta-blocker and to combinations useful therefor. The methods, compositions and combinations of the present invention can be used for reducing infarction in the heart (myocardial infarction) and the brain (stroke).

Abstract: The present invention relates to pharmaceutical compositions comprising at least one multifunctional phosphodiesterase inhibitor (MPDEI) and at least one adenosine uptake inhibitor. The present invention also relates to compositions comprising cilostazol and dipyridamole and their use.

Abstract: The present invention relates to pharmaceutical compositions comprising at least one multifunctional phosphodiesterase inhibitor (MPDEI) and at least one adenosine uptake inhibitor. The present invention also relates to compositions comprising cilostazol and dipyridamole and their use.