Patents by Inventor Yonghan Hu

Yonghan Hu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4,6-diamino-[1,7]naphthyridine-3-carbonitrile inhibitors of Tpl2 kinase and methods of making and using the same
    Publication number: 20060276498
    Abstract: The present invention provides compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, m and n are defined as described herein. The invention also provides methods of making the compounds of formula (I), and methods of treating inflammatory diseases, such as rheumatoid arthritis, in a mammal comprising administering a therapeutically effective amount of a compound of formula (I) to the mammal.
    Type: Application
    Filed: May 18, 2006
    Publication date: December 7, 2006
    Applicant: Wyeth
    Inventors: Neal Green, Lori Gavrin, Neelu Kaila, Yonghan Hu, Kristin Janz, Jennifer Thomason, Ariamala Gopalsamy, Steve Tam, Lih-Ling Lin, John Cuozzo, Dennis Powell
  • 3-Cyanoquinoline inhibitors of Tpl2 kinase and methods of making and using the same
    Publication number: 20060264460
    Abstract: The present invention provides compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, m and n are defined as described herein. The invention also provides methods of making the compounds of formula (I), and methods of treating inflammatory diseases, such as rheumatoid arthritis, in a mammal comprising administering a therapeutically effective amount of a compound of formula (I) to the mammal.
    Type: Application
    Filed: May 18, 2006
    Publication date: November 23, 2006
    Applicant: Wyeth
    Inventors: Neal Green, Yonghan Hu, Neelu Kaila, Kristin Janz, Jennifer Thomason, Huan-Qiu Li, Rajeev Hotchandani, Junjun Wu, Ariamala Gopalsamy, Steve Tam, Lih-Ling Lin, John Cuozzo, Satenig Guler, Adrian Huang, Jeffrey condon
  • Biaryl sulfonamides and methods for using same
    Publication number: 20050143422
    Abstract: The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.
    Type: Application
    Filed: December 1, 2004
    Publication date: June 30, 2005
    Applicant: Wyeth
    Inventors: Jeremy Levin, Thomas Rush, Frank Lovering, Yonghan Hu, Jianchang Li, Wei Li, Jun Wu, Rajeev Hotchandani, Jason Xiang, Xuemei Du, Derek Cole, Steve Tam
  • Biaryl sulfonamides and methods for using same
    Publication number: 20050130973
    Abstract: The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.
    Type: Application
    Filed: December 1, 2004
    Publication date: June 16, 2005
    Applicant: Wyeth
    Inventors: Jason Xiang, Steve Tam, Yonghan Hu, Phaik-Eng Sum, David How, Darrin Hopper, Matthew Vera, Joshua Sabatini, Thomas Rush, Elisabeth Morris, Katy Georgiadis
  • Compositions for organic synthesis on solid phase and methods of using the same
    Patent number: 6147159
    Abstract: A modified solid support for use in solid phase synthesis which comprises:a solid support having a linker group extending therefrom having the general formula: ##STR1## wherein R.sub.1 and R.sub.2 are each independently selected from the group consisting of alkyl, cycloalkyl, aryl, alkoxy, aryloxy, fluorine, chlorine, iodine and bromine.
    Type: Grant
    Filed: September 30, 1998
    Date of Patent: November 14, 2000
    Assignee: Argonaut Technologies
    Inventors: Yonghan Hu, Jeffrey W. Labadie, John Anthony Porco, Jr., Barry Martin Trost