Abstract: Provided are a method and control device for setting an operation route for an operation device, belonging to the field of agricultural crop protection operations. The method includes: displaying a map on a display interface, displaying target land plot information on the map, displaying a planned route for the target land plot on the map, and displaying a movable identifier on the map, the target land plot information including boundary information of the target land plot; in response to a drag operation by a user on the movable identifier, changing the position at which the movable identifier remains; according to the remain position, determining an operation route from the planned route.