Abstract: A method and mechanism for producing and executing self-steering program code. A method comprises analyzing program code and identifying portions which may be amenable to optimization. Having identified such a portion of code, at least one optimized version of the identified code is added to the program code. Additionally, a selection mechanism is added to the program code which is configured to select between two or more versions of the portion of code during runtime. The modified program code is then compiled with the added optimized version and the selection mechanism. During execution, monitoring of behavior of the code may be enabled or disabled. Based upon such monitored behavior, a different version of the code may be selected for execution.

Abstract: Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders.

Abstract: A method and system for identifying multi-block indirect memory access chains. A method may include identifying basic blocks between an entry point and an exit point of a procedure, where the procedure includes a control statement governing its execution. It may be determined whether a probability of execution of a given basic block relative to the control statement equals or exceeds a first threshold value. If so, a respective set of one or more chains of indirect memory accesses may be generated, where each chain includes at least a respective head memory access that does not depend for its memory address computation on another memory access within the given basic block. Chains may be joined across basic blocks dependent upon whether the relative execution probabilities of the blocks exceed a threshold value.

Abstract: Prefetch information is generated for multi-block indirect memory access chains. A method may include selecting a chain of indirect memory accesses of a procedure, the chain comprising a head access that does not depend for its address on another prefetch candidate memory access within the procedure and an indirect access that depends for its address on the head access. The method may further include determining a prefetch-ahead value for the chain, and generating a load operation corresponding to the head access that specifies a target memory address that is dependent upon the prefetch-ahead value and an address of the head access. The method may further include, for a terminal indirect access of the chain, generating a respective prefetch operation that is dependent for its address computation on results of preceding load operations in the same manner as its corresponding terminal indirect access depends upon preceding accesses in the chain.

Abstract: A method and mechanism for using threads in a computing system. A multithreaded computing system is configured to execute a first thread and a second thread. Responsive to the first thread detecting a launch point for a function, the first thread is configured to provide an indication to the second thread that the second thread may begin execution of a given function. The launch point of the function precedes an actual call point of the function in an execution sequence. The second thread is configured to initiate execution of the function in response to the indication. The function includes one or more inputs and the second thread uses anticipated values for each of the one or more inputs. When the first thread reaches a call point for the function, the first thread is configured to use a results of the second thread's execution, in response to determining the anticipated values used by the second thread were correct.

Abstract: The present invention is directed to compounds of formula (I) and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to intermediates used in making such compounds, pharmaceutical compositions containing such a compound, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.

Abstract: Novel benzamide compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.

Abstract: One embodiment of the present invention provides a system that generates code to perform anticipatory prefetching for data references. During operation, the system receives code to be executed on a computer system. Next, the system analyzes the code to identify data references to be prefetched. This analysis can involve: using a two-phase marking process in which blocks that are certain to execute are considered before other blocks; and analyzing complex array subscripts. Next, the system inserts prefetch instructions into the code in advance of the identified data references. This insertion can involve: dealing with non-constant or unknown stride values; moving prefetch instructions into preceding basic blocks; and issuing multiple prefetches for the same data reference.

Abstract: The present invention is directed to compounds represented by Formula (I) or a pharmaceutically acceptable salt, ester, or prodrug thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.

Abstract: One embodiment of the present invention provides a system that generates code to perform anticipatory prefetching for data references. During operation, the system receives code to be executed on a computer system. Next, the system analyzes the code to identify data references to be prefetched. This analysis can involve: using a two-phase marking process in which blocks that are certain to execute are considered before other blocks; and analyzing complex array subscripts. Next, the system inserts prefetch instructions into the code in advance of the identified data references. This insertion can involve: dealing with non-constant or unknown stride values; moving prefetch instructions into preceding basic blocks; and issuing multiple prefetches for the same data reference.

Abstract: Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders.

Abstract: One embodiment of the present invention provides a system for communicating and performing synchronization operations between a main thread and a helper-thread. The system starts by executing a program in a main thread. Upon encountering a loop which has associated helper-thread code, the system commences the execution of the code by the helper-thread separately and in parallel with the main thread. While executing the code by the helper-thread, the system periodically checks the progress of the main thread and deactivates the helper-thread if the code being executed by the helper-thread is no longer performing useful work. Hence, the helper-thread is executes in advance of where the main thread is executing to prefetch data items for the main thread without unnecessarily consuming processor resources or hampering the execution of the main thread.

Abstract: One embodiment of the present invention provides a system that generates code for software scouting the regions of a program. During operation, the system receives source code for a program. The system then compiles the source code. In the first step of the compilation process, the system identifies a first set of loops from a hierarchy of loops in the source code, wherein each loop in the first set of loops contains at least one effective prefetch candidate. Then, from the first set of loops, the system identifies a second set of loops where scout-mode prefetching is profitable. Next, for each loop in the second set of loops, the system produces executable code for a helper-thread which contains a prefetch instruction for each effective prefetch candidate. At runtime the helper-thread is executed in parallel with the main thread in advance of where the main thread is executing to prefetch data items for the main thread.

Abstract: Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders.

Abstract: The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.

Abstract: The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.

Abstract: The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.

Abstract: Novel benzamide compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.

Abstract: Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders.

Abstract: Novel benzamide compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.