Abstract: An ice maker of the present embodiment comprises: an upper tray including an upper tray body defining an upper chamber that is a portion of an ice chamber for generating ice; and a lower tray rotated relative to the upper tray based on a rotational center, and including a lower tray body defining a lower chamber that is another portion of the ice chamber, wherein a top surface of the lower tray body can contact a bottom surface of the upper tray body, the rotational center is disposed outside of the upper chamber and the lower chamber, the bottom surface of the upper tray body includes a first surface and a second surface disposed farther from the rotational center than the first surface, and before the top surface of the lower tray body contacts the bottom surface of the upper tray body, the second surface is lower than the first surface.

Abstract: A refrigerator includes a cabinet forming a storage space, a door configured to open or close the storage space, and an ice maker provided in the storage space or the door. The ice maker includes an upper tray including an upper chamber forming an upper portion of an ice chamber, a lower tray including a lower chamber forming a lower portion of the ice chamber, and an upper heater disposed along a circumference of the upper chamber so that at least two heating regions are formed at different positions in a vertical direction in the upper chamber.

Abstract: An ice maker of the present invention comprises: an upper tray defining an upper chamber that is a portion of an ice chamber, wherein an upper opening is provided in an upper side of the upper tray; a lower tray defining a lower chamber that is another portion of the ice chamber; a lower support supporting the lower tray and provided with a lower heater; and a control unit configured to operate the lower heater in an ice making process, wherein the control unit variably controls an output of the lower heater so that bubbles included in water in the ice chamber are gathered in a lowermost section in the ice making process.

Abstract: An ice maker includes an upper tray defining an upper chamber that is a portion of an ice chamber; a lower tray defining a lower chamber that is another portion of the ice chamber, where the lower tray is relatively rotatable relative to the upper tray; and an upper heater disposed around the upper tray, for providing heat to the upper chamber. The upper tray is made of a non-metal material and a flexible material, the upper heater is a DC heater receiving DC power, at least a portion of the upper tray is thicker than the lower tray, an accommodation part for accommodating the upper heater is formed on the upper tray, and at least a portion of the upper heater is disposed to vertically overlap the ice chamber in a state that the upper heater is accommodated in the accommodation part.

Abstract: An ice maker of the present invention comprises: an upper tray defining an upper chamber that is a portion of an ice chamber, wherein an upper opening is provided in an upper side of the upper tray; a lower tray defining a lower chamber that is another portion of the ice chamber; a lower support supporting the lower tray and provided with a lower heater; and a control unit configured to operate the lower heater in an ice making process, wherein the control unit variably controls an output of the lower heater so that bubbles included in water in the ice chamber are gathered in a lowermost section in the ice making process.

Abstract: Provided is a refrigerator including a cabinet having a refrigerating compartment and a freezing compartment defined therein, and an ice maker disposed in the freezing compartment, wherein the ice maker includes an upper tray made of an elastic material, and having a plurality of hemispherical upper chambers defined therein, a lower tray made of an elastic material, wherein the lower tray comes into contact with the upper tray by pivoting to define a plurality of spherical ice chambers therebetween, a driver for pivoting the lower tray to open and close the upper tray and the lower tray, and each rib formed along a circumference of each upper chamber or each lower chamber in contact with each other.

Abstract: An ice maker includes an upper assembly provided with an upper tray which has an upper chamber recessed upwardly to define an upper side of an ice chamber in which water is filled to generate ice, a lower assembly provided with a lower tray which has a lower chamber recessed downwardly to define a lower side of the ice chamber, and a lower supporter which supports a lower side of the lower tray, in which the lower assembly is rotatably connected to the upper assembly. The ice maker also includes an upper ejector provided with an upper ejecting pin which separates ice from the upper tray after ice-making is completed, in which the upper ejector is connected to the lower assembly to be interlocked with each other, such that when the lower assembly is rotated, the upper ejector is lifted and lowered.

Abstract: In a refrigerator, a cam of a cam gear rotating by a driving motor is provided with a structure protruding from an edge portion of a cam gear to a center, thereby increasing the thickness of a cam surface. Therefore, it is possible to reduce the magnitude of force directly transferred from the cam gear to a magnet lever.

Abstract: An ice maker includes first and second trays configured to form a plurality of ice chambers configured to make ice, an upper case including a cool air hole through which cool air passes, and a tray opening configured to allow the first tray to contact the cool air passing through the cool air hole, a driver configured to move the second tray, and a connector configured to transfer power of the driver to the second tray, wherein the upper case further includes the cool air guide configured to guide the cool air passing through the cool air hole toward the tray opening.

Abstract: A method controls a refrigerator including first and second trays defining an ice chamber, a driving unit for moving the second tray, an ice bin for storing ice produced in the ice chamber, and an ice-fullness detection means for detecting whether or not the ice bin is full of ice. The method includes supplying water to the ice chamber when the second tray is at a water-supply position, making ice after the second tray has moved to an ice-making position in an inverse direction after the water supply has been completed, determining whether the ice bin is full of ice after the ice making is completed, moving the second tray to an ice-separating position and then rotating in the inverse direction if it is not determined whether or not the ice bin is full of ice, and determining again whether the ice bin is full of ice after ice separation is completed.

Abstract: A refrigerator includes a cabinet forming a storage space, a door configured to open or close the storage space, and an ice maker provided in the storage space or the door. The ice maker includes an upper tray including an upper chamber forming an upper portion of an ice chamber, a lower tray including a lower chamber forming a lower portion of the ice chamber, and an upper heater disposed along a circumference of the upper chamber so that at least two heating regions are formed at different positions in a vertical direction in the upper chamber.

Abstract: The present invention relates to a refrigerator. An ice maker of the refrigerator according to this embodiment includes: an upper tray which is made of an elastic material and in which a plurality of hemispherical upper chamber are defined; and a lower tray which is made of an elastic material and in which a plurality of lower chambers, which rotate to be in close contact with the upper tray so as to provide spherical ice chambers, are defined.

Abstract: An ice maker of a refrigerator includes a tray assembly having an upper tray that defines upper portions of a plurality of ice making chambers. Each of the plurality of ice making chambers is configured to receive water and generate an ice piece. The tray assembly also includes a lower tray that is located vertically below the upper tray, that is configured to rotate relative to the upper tray, and that defines lower portions of the plurality of ice making chambers, wherein at least one of the upper tray or the lower tray comprises a flexible tray made of a flexible material. Additionally, a case is configured to accommodate the flexible tray to restrict a deformation of the flexible tray. A heater that is located between the case and the flexible tray is configured to supply heat to the plurality of ice making chambers through the flexible tray.

Abstract: Disclosed herein are matrix-free and in vivo-like glioblastoma organoids (GBOs) developed using patient-derived xenograft GBM lines in small-scale bioreactors and a method of scalable biomanufacture thereof. Shear stress, agitation rate, and media supplements can be optimized to produce highly reproducible GBOs over 1 mm diameter within 4-5 weeks. GBOs can exhibit high stemness and strong cell-to-cell interactions compared to conventional tumorsphere cultures. They can display spatial gradients of HIF-1? positive hypoxic cores where CD133-positive cells resided and spatially heterogeneous expression of NOTCH and its ligands. A self-established, hierarchically organized, and heterogeneous TME by GBM transdifferentiation into endothelial cells, pericytes, and astrocytes can also be observed. Collectively, the ability to biomanufacture uniformly sized GBOs that recapitulate in vivo GBM TME features that can serve as an improved GBM in vitro model is demonstrated herein.

Abstract: Systems and methods for utilizing a universal denoiser for improving Ebeam images are disclosed. A method can include obtaining a base set of Ebeam images from a plurality of domains within a process environment; and applying a universal denoiser to the base set of Ebeam images to generate an enhanced set of Ebeam images, wherein the enhanced set of Ebeam images has a higher quality than the base set of Ebeam images and accounts for a domain type of each of the plurality of domains.

Abstract: Systems and methods for detecting and quantifying images are disclosed. Systems and methods can include a metrology platform comprising: a customizable or user-configurable pipeline that is configured to enable a user to automatically and longitudinally obtain a plurality of metrology metrics from a process environment; and a graphical user interface (GUI) for implementing the pipeline, wherein the GUI comprises (1) a plurality of graphical functions configured to permit the user to interact with or to customize the pipeline and (2) one or more visual display areas configured to display the plurality of metrology metrics and a set of metrology images associated thereof.

Abstract: A display apparatus in one example can include a plurality of light emitting diodes, and a plurality of driving devices to output driving signals for driving the plurality of light emitting diodes. Each of the plurality of driving devices bypasses input common command data and outputs the common command data to an adjacent driving device. Accordingly, a transmission period of data transmitted to the plurality of driving devices can be reduced.

Abstract: An ice maker of this embodiment comprises: an upper tray defining an upper chamber that is a portion of an ice chamber; a lower tray defining a lower chamber that is another portion of the ice chamber, wherein the lower tray is relatively rotatable relative to the upper tray; and an upper heater disposed around the upper tray, for providing heat to the upper chamber, wherein the upper tray is made of a non-metal material and a flexible material, the upper heater is a DC heater receiving DC power, at least a portion of the upper tray is thicker than the lower tray, an accommodation part for accommodating the upper heater is formed on the upper tray, and at least a portion of the upper heater is disposed to vertically overlap the ice chamber in a state that the upper heater is accommodated in the accommodation part.

Abstract: A refrigerator includes a cabinet, an ice maker configured to make spherical ice, and an ice bin for storing the ice. The ice maker includes an upper assembly including a plurality of hemispherical upper chambers, a lower assembly disposed below and pivotably coupled to the upper assembly, where the lower assembly includes a plurality of hemispherical lower chambers that are configured to come in contact with the plurality of hemispherical upper chambers to define a plurality of spherical ice chambers, a driver configured to pivot the lower assembly, and an ice-full state detection lever that is coupled to and configured to be pivoted by the driver, where the ice-full state detection lever is configured to pivot in the same direction as the lower assembly to detect whether the ice bin is in an ice-full state.

Abstract: An ice maker of a refrigerator includes an upper assembly having an upper tray that defines upper portions of a plurality of ice making chambers as well as a lower assembly located vertically below the upper assembly that is configured to rotate relative to the upper assembly. The lower assembly includes a lower tray that defines lower portions of the plurality of ice making chambers. Each of the plurality of ice making chambers is configured to receive water when the lower assembly rotates relative to the upper assembly and generate an ice piece within when the upper and lower portions of the ice making chambers are joined. The lower tray includes a deformable portion that is configured to, based on an outward expansion of the ice piece within the ice making chamber during ice generation, change from a first shape to a second shape.