Patents by Inventor Yongjin Li

Yongjin Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12233382
    Abstract: A preparation method of an antifouling and hydrophilic polyethersulfone ultrafiltration membrane includes through the 60Co-? radiation grafting chemical modification method, evenly distributing an ionic liquid on a surface of a polyethersulfone material, wherein the ionic liquid containing unsaturated bonds is connected with the polyethersulfone material through chemical bonds, and then obtaining an asymmetric porous membrane by the immersion-precipitation phase transformation method, and finally performing Soxhlet extraction on the porous membrane, so as to migrate the grafted ionic liquid from an interior of the porous membrane to a surface of the porous membrane to be enriched, so that the adsorption and antibacterial properties of the porous membrane are improved. A mass ratio of the ionic liquid to the polyethersulfone material is in a range of (2-11):100.
    Type: Grant
    Filed: November 30, 2021
    Date of Patent: February 25, 2025
    Assignee: HANGZHOU NORMAL UNIVERSITY
    Inventors: Yongjin Li, Chunjun Ni, Xin Zheng
  • Publication number: 20240247065
    Abstract: The present disclosure describes methods of treatment of cancer in patients with altered activity or amount of a SETD2 biomarker with a treatment regimen comprising an antagonist of Programmed Death 1 receptor (PD-1).
    Type: Application
    Filed: May 16, 2022
    Publication date: July 25, 2024
    Applicant: MERCK SHARP & DOHME LLC
    Inventors: Razvan CRISTESCU, Elisha DETTMAN, Yongjin LI, Karla Gabriela RODRIGUEZ-LOPEZ, Michael NEBOZHYN, Rodolfo Fleury PERINI, Raluca Andreia PREDOIU, Yiwei ZHANG
  • Patent number: 11932717
    Abstract: Disclosed are a green synthesis method of an antibacterial super-porous hydrogel, a product of the antibacterial super-porous hydrogel and an application of the antibacterial super-porous hydrogel to degradation of various pollutants in wastewater treatment. The super-porous hydrogel based on poly (ionic liquid) is prepared by copolymerization of an imidazole type ionic liquid with double bonds and polyethylene glycol diacrylate (PEGDA) as a cross-linker. In the reaction system, water is a good solvent for the monomer ionic liquid and PEGDA, but a poor solvent for the poly (ionic liquid); when an initial concentration of the ionic liquid is higher than 25%, the phase separation typically proceeds through poly(ionic liquid) formation, interconnected networks with macroporous structure could be obtained by photo-crosslinking.
    Type: Grant
    Filed: May 23, 2023
    Date of Patent: March 19, 2024
    Assignee: Hangzhou Normal University
    Inventors: Yuanyuan Liang, Yongjin Li
  • Publication number: 20230322997
    Abstract: Disclosed are a green synthesis method of an antibacterial super-porous hydrogel, a product of the antibacterial super-porous hydrogel and an application of the antibacterial super-porous hydrogel to degradation of various pollutants in wastewater treatment. The super-porous hydrogel based on poly (ionic liquid) is prepared by copolymerization of an imidazole type ionic liquid with double bonds and polyethylene glycol diacrylate (PEGDA) as a cross-linker. In the reaction system, water is a good solvent for the monomer ionic liquid and PEGDA, but a poor solvent for the poly (ionic liquid); when an initial concentration of the ionic liquid is higher than 25%, the phase separation typically proceeds through poly(ionic liquid) formation, interconnected networks with macroporous structure could be obtained by photo-crosslinking.
    Type: Application
    Filed: May 23, 2023
    Publication date: October 12, 2023
    Inventors: Yuanyuan LIANG, Yongjin LI
  • Publication number: 20220080367
    Abstract: A preparation method of an antifouling and hydrophilic polyethersulfone ultrafiltration membrane includes through the 60Co-? radiation grafting chemical modification method, evenly distributing an ionic liquid on a surface of a polyethersulfone material, wherein the ionic liquid containing unsaturated bonds is connected with the polyethersulfone material through chemical bonds, and then obtaining an asymmetric porous membrane by the immersion-precipitation phase transformation method, and finally performing Soxhlet extraction on the porous membrane, so as to migrate the grafted ionic liquid from an interior of the porous membrane to a surface of the porous membrane to be enriched, so that the adsorption and antibacterial properties of the porous membrane are improved. A mass ratio of the ionic liquid to the polyethersulfone material is in a range of (2-11):100.
    Type: Application
    Filed: November 30, 2021
    Publication date: March 17, 2022
    Inventors: Yongjin Li, Chunjun Ni, Xin Zheng
  • Publication number: 20200369876
    Abstract: A transparent and heat-resistant polycarbonate (PC) composite and a preparation method thereof. The PC composite is a blend of a PC, a polyarylester (PAR) and an organic salt. The preparation method includes: drying the PC and the PAR each under vacuum at 80-120° C. for 24-48 h; adding the dried PC, the dried PAR and the organic salt into a melt blending device at a mass ratio of (60-90):(40-10):(0.3-3), and performing melt blending at 250-300° C. to obtain a mixture; and discharging the mixture from the melt blending device, and cooling to normal temperature to obtain a PC composite.
    Type: Application
    Filed: April 24, 2020
    Publication date: November 26, 2020
    Inventors: Yongjin Li, Huihui Xu
  • Patent number: 9512280
    Abstract: Provided are: an organic/inorganic composite, and a manufacturing method therefor; and a dental material and bone substitute material manufactured using the organic/inorganic composite. The organic/inorganic composite includes: (A) 100 parts by mass of a thermoplastic resin containing as a main component at least one kind selected from a polyarylketone resin and a polysulfone resin; and (B) 60 to 300 parts by mass of an inorganic particle mixture dispersed in the thermoplastic resin, in which the inorganic particle mixture contains inorganic particles each having a particle diameter of from 200 to 700 nm at a content of 25 vol % or more, and inorganic particles each having a particle diameter of from 40 to 100 nm at a content of 10 vol % or more.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: December 6, 2016
    Assignees: TOKUYAMA DENTAL CORPORATION, NATIONAL IINSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Jun-ichiro Yamagawa, Hiroshi Shimizu, Yongjin Li
  • Patent number: 9199393
    Abstract: A high-shear melt-kneader includes a high-shear unit (20) having an internal feedback-type screw (23) configured to apply high-shear stress to a melted resin, resin pressure sensors (33) for configured to detect a front portion resin pressure in the vicinity of an inlet of the internal feedback-type screw and a rear portion resin pressure in the vicinity of an outlet, and a control device configured to appropriately control a material supplying amount, a material temperature, a kneading time, and a screw rotation speed according to pressure values detected by the sensors. The control device controls the conditions such that waveforms with the lapse of time of the front and rear portion resin pressures are similar to each other and show variation to a steady state after formation of a predetermined peak value, and the front and rear portion resin pressures form a predetermined pressure difference with the lapse of time.
    Type: Grant
    Filed: February 2, 2010
    Date of Patent: December 1, 2015
    Assignee: NIIGATA MACHINE TECHNO CO., LTD.
    Inventors: Hiroshi Shimizu, Yongjin Li, Yukio Yoshizawa, Takayuki Takahashi, Ken-ichi Toyoshima
  • Patent number: 8975336
    Abstract: It is an object of the present invention to obtain an optically transparent nano-dispersed polymer blend extrudate and a transparent resin having a microscopic dispersion structure in which incompatible polymer blend is melted and kneaded, one of resins is formed into a matrix, a size of dispersed phase of the other resin is controlled to 300 nm or less, more preferably 100 nm or less. Extra additive such as a compatibilizer is not added. When the incompatible polymer blend is melted and kneaded using a high shearing and forming apparatus having an inner feedback type screw under a condition that the screw rotation speed is 600 rpm to 3000 rpm, the rotation speed of the inner feedback type screw is increased, the kneading time is set under constant rotation speed, the high shearing forming condition is adjusted, and a structure in which a size of dispersed phase is controlled to 300 nm or less, more preferably 100 nm or less is formed.
    Type: Grant
    Filed: November 26, 2009
    Date of Patent: March 10, 2015
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Hiroshi Shimizu, Yongjin Li
  • Patent number: 8937126
    Abstract: Disclosed is a novel ternary aliphatic polycarbonate blend derived from carbon dioxide, which is mainly composed of an aliphatic polycarbonate. Also disclosed is a process for producing the ternary aliphatic polycarbonate blend. A methacrylic resin or an aliphatic polyester is incorporated, as a second component, into an aliphatic polycarbonate to produce a blend, and a vinyl resin is added, as a third component, to the blend at a specified ratio, thereby producing a novel ternary aliphatic polycarbonate blend derived from carbon dioxide and having excellent mechanical properties that cannot be achieved by binary blends.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: January 20, 2015
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Hiroshi Shimizu, Yongjin Li
  • Publication number: 20150011673
    Abstract: Provided are: an organic/inorganic composite, and a manufacturing method therefor; and a dental material and bone substitute material manufactured using the organic/inorganic composite. The organic/inorganic composite includes: (A) 100 parts by mass of a thermoplastic resin containing as a main component at least one kind selected from a polyarylketone resin and a polysulfone resin; and (B) 60 to 300 parts by mass of an inorganic particle mixture dispersed in the thermoplastic resin, in which the inorganic particle mixture contains inorganic particles each having a particle diameter of from 200 to 700 nm at a content of 25 vol % or more, and inorganic particles each having a particle diameter of from 40 to 100 nm at a content of 10 vol % or more.
    Type: Application
    Filed: November 20, 2012
    Publication date: January 8, 2015
    Applicant: Tokuyama Dental Corporation
    Inventors: Jun-ichiro Yamagawa, Hiroshi Shimizu, Yongjin Li
  • Patent number: 8415423
    Abstract: A melt-kneaded product includes: a disperse medium selected from an a rubber, elastomer, thermoplastic resin, or thermosetting resin; and a filling material constituted by nano-size filler particles having a mutually aggregating nature, said nano-size filler particles being uniformly dispersed in the disperse medium.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: April 9, 2013
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Hiroshi Shimizu, Yongjin Li
  • Patent number: 8349953
    Abstract: The invention provides a method of obtaining a compatible resin blend from at least two incompatible resins which are not conventionally blended with each other. The blend of an incompatible resins is dissolved at a molecular level by being melted and sheared under a high shearing rate by rotating a screw without adding a compatibilizer or the like.
    Type: Grant
    Filed: August 17, 2006
    Date of Patent: January 8, 2013
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Hiroshi Shimizu, Yongjin Li, Toshiyuki Imoto
  • Publication number: 20120327737
    Abstract: The invention provides a method of obtaining a compatible resin blend from at least two incompatible resins which are not conventionally blended with each other. The blend of an incompatible resins is dissolved at a molecular level by being melted and sheared under a high shearing rate by rotating a screw without adding a compatibilizer or the like.
    Type: Application
    Filed: September 6, 2012
    Publication date: December 27, 2012
    Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Hiroshi Shimizu, Yongjin Li, Toshiyuki Imoto
  • Publication number: 20120053282
    Abstract: Disclosed is a novel ternary aliphatic polycarbonate blend derived from carbon dioxide, which is mainly composed of an aliphatic polycarbonate. Also disclosed is a process for producing the ternary aliphatic polycarbonate blend. A methacrylic resin or an aliphatic polyester is incorporated, as a second component, into an aliphatic polycarbonate to produce a blend, and a vinyl resin is added, as a third component, to the blend at a specified ratio, thereby producing a novel ternary aliphatic polycarbonate blend derived from carbon dioxide and having excellent mechanical properties that cannot be achieved by binary blends.
    Type: Application
    Filed: November 5, 2009
    Publication date: March 1, 2012
    Applicant: National Institute of Advanced Industrial Science and technology
    Inventors: Hiroshi Shimizu, Yongjin Li
  • Publication number: 20110292756
    Abstract: A high-shear melt-kneader includes a high-shear unit (20) having an internal feedback-type screw (23) configured to apply high-shear stress to a melted resin, resin pressure sensors (33) for configured to detect a front portion resin pressure in the vicinity of an inlet of the internal feedback-type screw and a rear portion resin pressure in the vicinity of an outlet, and a control device configured to appropriately control a material supplying amount, a material temperature, a kneading time, and a screw rotation speed according to pressure values detected by the sensors. The control device controls the conditions such that waveforms with the lapse of time of the front and rear portion resin pressures are similar to each other and show variation to a steady state after formation of a predetermined peak value, and the front and rear portion resin pressures form a predetermined pressure difference with the lapse of time.
    Type: Application
    Filed: February 2, 2010
    Publication date: December 1, 2011
    Inventors: Hiroshi Shimizu, Yongjin Li, Yukio Yoshizawa, Takayuki Takahashi, Ken-ichi Toyoshima
  • Publication number: 20110282006
    Abstract: It is an object of the present invention to obtain an optically transparent nano-dispersion polymer blend extrudate and a transparent resin having a microscopic dispersion structure in which incompatible polymer blend is melted and kneaded, one of resins is formed into a matrix, a size of dispersed phase of the other resin is controlled to 300 nm or less, more preferably 100 nm or less. Extra additive such as a compatibilizer is not added. When the incompatible polymer blend is melted and kneaded using a high shearing and forming apparatus having an inner feedback type screw under a condition that the screw rotation speed is 600 rpm to 3000 rpm, the rotation speed of the inner feedback type screw is increased, the kneading time is set under constant rotation speed, the high shearing forming condition is adjusted, and a structure in which a size of dispersed phase is controlled to 300 nm or less, more preferably 100 nm or less is formed.
    Type: Application
    Filed: November 26, 2009
    Publication date: November 17, 2011
    Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Hiroshi Shimizu, Yongjin Li
  • Patent number: 8048948
    Abstract: A melt-kneading method for filling material-containing resin or elastomer includes: a step of preparing a filling material as a filler and a resin or elastomer comprising an incompatible blend; and a step of introducing the filling material-containing resin or elastomer into a material feed part provided at an end of a cylindrical melt-kneading part having a heater and provided with a screw, and then melt-kneading the filling material-containing resin or elastomer under conditions where the rotation speed of the screw is about 600 rpm to about 3,000 rpm and its shear rate is about 900 to about 4,500 sec?1, thereby forming a co-continuous structure comprising the incompatible blend.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: November 1, 2011
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Hiroshi Shimizu, Yongjin Li, Li Zhao
  • Publication number: 20110124793
    Abstract: A melt-kneaded product includes: a disperse medium selected from an a rubber, elastomer, thermoplastic resin, or thermosetting resin; and a filling material constituted by nano-size filler particles having a mutually aggregating nature, said nano-size filler particles being uniformly dispersed in the disperse medium.
    Type: Application
    Filed: January 26, 2011
    Publication date: May 26, 2011
    Applicant: National Institute of Advanced Industrial Science and Technology
    Inventors: Hiroshi SHIMIZU, Yongjin LI
  • Patent number: D889401
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: July 7, 2020
    Assignee: Shenzhen Lepower Electronic Co., Ltd.
    Inventor: Yongjin Li