Patents by Inventor Yongjing CHEN
Yongjing CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11802857Abstract: The eluent used in IC separation contains non-volatile salt which is not compatible with electrospray ionization-mass spectrometry (ESI-MS). A suppressor is required to convert the non-volatile salt into water or the volatile acid form (i.e. acetic acid). When the suppressor fails, the non-volatile salts will enter the MS and cause extensive shutdown and maintenance of the mass spectrometer. The suppressor voltage derivative is used to evaluate the most common suppressor failure modes, including disruption of regenerant flow and excessive backpressure on the suppressor due to clogging in the downstream, and to trigger the eluent pump to stop the eluent flow or to trigger the auxiliary valve to switch the flow to the mass spectrometer from eluent to water.Type: GrantFiled: December 8, 2021Date of Patent: October 31, 2023Assignee: Dionex CorporationInventor: Yongjing Chen
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Publication number: 20230341361Abstract: A suppressor comprising one or more channels, a flow path for each of the channels, and one or more measurement probes positioned in the flow path is described. Each channel includes an inlet and an outlet. Each flow path includes an upstream path to the inlet, a channel stream path through the channel and connecting the inlet to the outlet, and a downstream path from the outlet. A system including the suppressor as well as methods implementing the suppressor are also described.Type: ApplicationFiled: March 20, 2023Publication date: October 26, 2023Inventors: Yongjing Chen, Yan Liu
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Publication number: 20230194485Abstract: An analytical system comprises a chromatography column configured to separate a sample into one or more analytes; an ion removal device configured to remove at least ions of one charge from the mobile phase, the ion removal device fluidly coupled to an output of the chromatography column; an ion selective sensor configured to measure a signal corresponding to an activity of the ions of one charge in the mobile phase, the ion selective sensor fluidly coupled to an output of the ion removal device; an optional diverter valve that can interrupt the flow of the mobile phase; and a microprocessor configured to monitor the signal of the ion selective sensor and to either switch the optional diverter valve to interrupt the flow of the mobile phase or turn off the pump when the signal is greater than a predetermined threshold.Type: ApplicationFiled: December 17, 2021Publication date: June 22, 2023Inventors: Yongjing Chen, Yan Liu
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Publication number: 20230176019Abstract: The eluent used in IC separation contains non-volatile salt which is not compatible with electrospray ionization-mass spectrometry (ESI-MS). A suppressor is required to convert the non-volatile salt into water or the volatile acid form (i.e. acetic acid). When the suppressor fails, the non-volatile salts will enter the MS and cause extensive shutdown and maintenance of the mass spectrometer. The suppressor voltage derivative is used to evaluate the most common suppressor failure modes, including disruption of regenerant flow and excessive backpressure on the suppressor due to clogging in the downstream, and to trigger the eluent pump to stop the eluent flow or to trigger the auxiliary valve to switch the flow to the mass spectrometer from eluent to water.Type: ApplicationFiled: December 8, 2021Publication date: June 8, 2023Inventor: Yongjing Chen
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Publication number: 20230165907Abstract: The use of a muscle stem cell in the preparation of a drug for preventing, alleviating and treating metabolic disorders, and a pharmaceutical composition for humans and animals, wherein the pharmaceutical composition comprises the muscle stem cell as a first active ingredient, a second active ingredient for regulating the glucose metabolism, and a pharmaceutically acceptable carrier.Type: ApplicationFiled: April 19, 2021Publication date: June 1, 2023Applicant: SOOCHOW UNIVERSITYInventors: Yufang Shi, Lijuan Cao, Jiankai Fang, Yongjing Chen, Ying Wang
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Publication number: 20230134486Abstract: Buffer generators are described based on electrodialytic devices. The methods of using these devices can generate buffers for diverse applications, including separations, e.g., HPLC and ion chromatography. Also provided are chromatographic devices including the buffer generators, generally located upstream from a chromatography column, sample injector valve or both.Type: ApplicationFiled: September 6, 2022Publication date: May 4, 2023Inventors: Purnendu K. Dasgupta, Yongjing Chen, Kannan Srinivasan
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Publication number: 20220360509Abstract: A system is disclosed for network management automation using network intent or adaptive monitoring automation. Network intent (NI) represents a network design and baseline configuration for that network or network devices with an ability to diagnose deviation from the baseline configuration. The NI can be automated to update and replicate the diagnosis. The monitoring of the network can be adapted to capture network problems in advance with adaptive monitoring automation.Type: ApplicationFiled: April 26, 2022Publication date: November 10, 2022Applicant: NetBrain Technologies, Inc.Inventors: Lingping Gao, Peng Zhao, Yawei Wang, Hongwei Liu, Yongjing Chen, Lianchao Jin, Weibo Li, Pu Cheng, Guangdong Liao
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Patent number: 11466373Abstract: Buffer generators are described based on electrodialytic devices. The methods of using these devices can generate buffers for diverse applications, including separations, e.g., HPLC and ion chromatography. Also provided are chromatographic devices including the buffer generators, generally located upstream from a chromatography column, sample injector valve or both.Type: GrantFiled: May 25, 2018Date of Patent: October 11, 2022Assignees: Board of Regents, The University of Texas System, Dionex CorporationInventors: Purnendu K. Dasgupta, Yongjing Chen, Kannan Srinivasan
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Patent number: 10208387Abstract: An electrodialytic buffer generator is described. The buffer generator may include a central buffer-generating channel having an inlet and outlet, a second chamber, and a third chamber. The buffer-generating channel, the second chamber, and the third chamber may each include an electrode. The buffer generator may also include a first ion exchange barrier and a second ion exchange barrier. The first ion exchange barrier can be disposed between the second chamber and the buffer-generating channel. The second ion exchange barrier can be disposed between the third chamber and the buffer-generating channel.Type: GrantFiled: January 25, 2017Date of Patent: February 19, 2019Assignees: Board of Regents, The University of Texas System, Dionex CorporationInventors: Purnendu K. Dasgupta, Yongjing Chen, Kannan Srinivasan
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Publication number: 20180274111Abstract: Buffer generators are described based on electrodialytic devices. The methods of using these devices can generate buffers for diverse applications, including separations, e.g., HPLC and ion chromatography. Also provided are chromatographic devices including the buffer generators, generally located upstream from a chromatography column, sample injector valve or both.Type: ApplicationFiled: May 25, 2018Publication date: September 27, 2018Inventors: Purnendu K. Dasgupta, Yongjing Chen, Kannan Srinivasan
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Patent number: 10023965Abstract: Buffer generators are described based on electrodialytic devices. The methods of using these devices can generate buffers for diverse applications, including separations, e.g., HPLC and ion chromatography. Also provided are chromatographic devices including the buffer generators, generally located upstream from a chromatography column, sample injector valve or both.Type: GrantFiled: August 23, 2012Date of Patent: July 17, 2018Assignees: Board of Regents, The University of Texas System, Dionex CorporationInventors: Purnendu K. Dasgupta, Yongjing Chen, Kannan Srinivasan
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Publication number: 20170130345Abstract: An electrodialytic buffer generator is described. The buffer generator may include a central buffer-generating channel having an inlet and outlet, a second chamber, and a third chamber. The buffer-generating channel, the second chamber, and the third chamber may each include an electrode. The buffer generator may also include a first ion exchange barrier and a second ion exchange barrier. The first ion exchange barrier can be disposed between the second chamber and the buffer-generating channel. The second ion exchange barrier can be disposed between the third chamber and the buffer-generating channel.Type: ApplicationFiled: January 25, 2017Publication date: May 11, 2017Inventors: Purnendu K. Dasgupta, Yongjing Chen, Kannan Srinivasan
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Patent number: 9580822Abstract: An electrodialytic buffer generator is described. The buffer generator may include a central buffer-generating channel having an inlet and outlet, a second chamber, and a third chamber. The buffer-generating channel, the second chamber, and the third chamber may each include an electrode. The buffer generator may also include a first ion exchange barrier and a second ion exchange barrier. The first ion exchange barrier can be disposed between the second chamber and the buffer-generating channel. The second ion exchange barrier can be disposed between the third chamber and the buffer-generating channel.Type: GrantFiled: August 23, 2012Date of Patent: February 28, 2017Assignees: Board of Regents, The University of Texas System, Dionex CorporationInventors: Purnendu K. Dasgupta, Yongjing Chen, Kannan Srinivasan
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Publication number: 20130220814Abstract: Buffer generators are described based on electrodialytic devices. The methods of using these devices can generate buffers for diverse applications, including separations, e.g., HPLC and ion chromatography. Also provided are chromatographic devices including the buffer generators, generally located upstream from a chromatography column, sample injector valve or both.Type: ApplicationFiled: August 23, 2012Publication date: August 29, 2013Applicants: DIONEX CORPORATION, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Purnendu K. DASGUPTA, Yongjing CHEN, Kannan SRINIVASAN
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Publication number: 20130048498Abstract: An electrodialytic buffer generator is described. The buffer generator may include a central buffer-generating channel having an inlet and outlet, a second chamber, and a third chamber. The buffer-generating channel, the second chamber, and the third chamber may each include an electrode. The buffer generator may also include a first ion exchange barrier and a second ion exchange barrier. The first ion exchange barrier can be disposed between the second chamber and the buffer-generating channel. The second ion exchange barrier can be disposed between the third chamber and the buffer-generating channel.Type: ApplicationFiled: August 23, 2012Publication date: February 28, 2013Applicants: DIONEX CORPORATION, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Purnendu K. DASGUPTA, Yongjing CHEN, Kannan SRINIVASAN
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Patent number: D930642Type: GrantFiled: September 25, 2020Date of Patent: September 14, 2021Inventor: Yongjing Chen
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Patent number: D949139Type: GrantFiled: September 25, 2020Date of Patent: April 19, 2022Inventor: Yongjing Chen