Patents by Inventor Yong Jun Guo

Yong Jun Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Odc allelic analysis method for assessing carcinogenic susceptibility
    Patent number: 6753422
    Abstract: The invention includes kits and methods for assessing the susceptibility of a mammal such as a human for carcinogenesis. The methods comprise determining whether the mammal comprises a certain allele of the mammal's odc gene. The methods include use of a probe which binds specifically with a portion of one allele of the odc gene and which comprises a fluorescent label and a fluorescence quencher. The methods also include use of such a probe and a polymerase enzyme for amplifying a portion of the odc gene, the polymerase having exonuclease activity whereby the probe can be nucleolytically degraded.
    Type: Grant
    Filed: July 24, 2001
    Date of Patent: June 22, 2004
    Inventors: Thomas G. O'Brien, Yong Jun Guo
  • Odc allelic analysis method for assessing carcinogenic susceptibility
    Publication number: 20020081611
    Abstract: The invention includes kits and methods for assessing the susceptibility of a mammal such as a human for carcinogenesis. The methods comprise determining whether the mammal comprises a certain allele of the mammal's odc gene. The methods include use of a probe which binds specifically with a portion of one allele of the odc gene and which comprises a fluorescent label and a fluorescence quencher. The methods also include use of such a probe and a polymerase enzyme for amplifying a portion of the odc gene, the polymerase having exonuclease activity whereby the probe can be nucleolytically degraded.
    Type: Application
    Filed: July 24, 2001
    Publication date: June 27, 2002
    Applicant: Lankenau Medical Research Center
    Inventors: Thomas G. O'Brien, Yong Jun Guo
  • ODC allelic analysis method for assessing carcinogenic susceptibility
    Patent number: 6277581
    Abstract: The invention includes kits and methods for assessing the susceptibility of a mammal such as a human for carcinogenesis. The methods comprise determining whether the mammal comprises a certain allele of the mammal's odc gene. The methods include use of a probe which binds specifically with a portion of one allele of the odc gene and which comprises a fluorescent label and a fluorescence quencher. The methods also include use of such a probe and a polymerase enzyme for amplifying a portion of the odc gene, the polymerase having exonuclease activity whereby the probe can be nucleolytically degraded.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: August 21, 2001
    Assignee: Lankenau Medical Research Center
    Inventors: Thomas G. O'Brien, Yong Jun Guo