Abstract: The invention relates to a process for the production of an [18F]fluorohaloalkane which comprises treatment of a solid support-bound precursor of formula (I): SOLID SUPPORT-LINKER-SO2—O—(CH2)nX??(I) wherein n is an integer of from 1 to 7 and X is chloro, bromo or iodo; with 18F? to produce the [18F]fluorohaloalkane of formula (II) 18F—(CH2)n—X??(II) wherein n and X are as defined for the compound of formula (I), optionally followed by (i) removal of excess 18F?, for example by ion-exchange chromatography; and/or (ii) removal of organic solvent.

Abstract: The invention relates to a process for the production of an [18F]fluorohaloalkane which comprises treatment of a solid support-bound precursor of formula (I): SOLID SUPPORT-LINKER-SO2—O—(CH2)nX (I) wherein n is an integer of from (1) to (7) and X is chloro, bromo or iodo; with 18F? to produce the [18F]fluorohaloalkane of formula (II) 18F—(CH2)n—X (II) wherein n and X are as defined for the compound of formula (I), optionally followed by (i) removal of excess 18F?, for example by ion-exchange chromatography; and/or (ii) removal of organic solvent.

Abstract: A process for fabricating a polymer based circuit by the following steps. A mold of a design is formed through a lithography process. The design is transferred to a polymer substrate through a hot embossing process. A metal layer is then deposited over at least part of said design and at least one electrical lead is connected to said metal layer.

Abstract: The invention provides a process for preparation of a fluorohaloalkane, preferably an [18F]fluorohaloalkane of formula (I) wherein X is halo and n is an integer of from 1 to 6; which comprises: reaction of the corresponding organosilicon compound of formula (II): wherein n is as defined for the compound of formula (I); and R?, R?, and R?? are independently selected from C1-6 alkyl and C1-6 haloalkyl; and R? may alternatively be the group: with a compound of formula (III): wherein X is as defined for the compound of formula (I) and Y is halo. Intermediates having use in such processes are also claimed.

Abstract: The invention relates to a process for the production of an [18F]fluorohaloalkane which comprises treatment of a solid support-bound precursor of formula (I): SOLID SUPPORT-LINKER-SO2—O—(CH2)nX (I) wherein n is an integer of from (1) to (7) and X is chloro, bromo or iodo; with 18F? to produce the [18F]fluorohaloalkane of formula (II) 18F—(CH2)nX (II) wherein n and X are as defined for the compound of formula (I), optionally followed by (i) removal of excess 18F?, for example by ion-exchange chromatography; and/or (ii) removal of organic solvent.

Abstract: The present invention includes a device comprising a plurality of interconnected computers. Each of the plurality of interconnected computers preferably includes a storage device that is configured to store a cookie entry when the computer user visits a web page. The cookie entry preferably comprises a path name, a description of web page content, and a uniform resource locator of the web page. The device further includes at least one processor in communication with the plurality of interconnected computers. The processor is preferably configured to accept a search query from a computer user, compare the search query with the cookie entry, and provide the computer user with the uniform resource locator of the cookie entry that match the search query.

Abstract: The present invention includes a method of composing at least one literary work. The method includes establishing a story theme; providing a plurality of interconnected computers; allowing users to use the plurality of interconnected computers; forming a cast of authors from the users of the plurality of interconnected computers; and allowing the cast of authors to compose a script based on the story theme.

Abstract: Methods and apparatuses for facilitating online communications are described. One method comprises allowing at least one message author to compose a message; allowing the message author to provide a description of the message; defining a plurality of message types, each type distinguishable by its message description; associating the author's message with a message type from the plurality of defined message types; allowing at least one potential message recipient to enter a profile, the profile comprising an indication of the type of message the potential message recipient desires to receive; and, associating the author's message with at least one potential message recipient profile based on the message type.