Patents by Inventor Yongku Cho

Yongku Cho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Blue-light-activated ion channel polypeptides and uses thereof
    Patent number: 10392426
    Abstract: The invention, in some aspects relates to light-activated ion channel polypeptides and encoding nucleic acids and also relates in part to compositions comprising light-activated ion channel polypeptides and methods using light-activated ion channel polypeptides to alter cell activity and function.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: August 27, 2019
    Assignees: Massachusetts Institute of Technology, The Governors of the University of Alberta, President and Fellows of Harvard College
    Inventors: Nathan Klapoetke, Edward Boyden, Yongku Cho, Brian Y. Chow, Gane K. S. Wong, Adam E. Cohen, Daniel R. Hochbaum
  • BLUE LIGHT-ACTIVATED ION CHANNEL MOLECULES AND USES THEREOF
    Publication number: 20170174730
    Abstract: The invention, in some aspects relates to light-activated ion channel polypeptides and encoding nucleic acids and also relates in part to compositions comprising light-activated ion channel polypeptides and methods using light-activated ion channel polypeptides to alter cell activity and function.
    Type: Application
    Filed: March 1, 2017
    Publication date: June 22, 2017
    Applicants: Massachusetts Institute of Technology, The Governors of the University of Alberta, President and Fellows of Harvard College
    Inventors: Nathan Klapoetke, Edward Boyden, Yongku Cho, Brian Y. Chow, Gane K.S. Wong, Adam E. Cohen, Daniel R. Hochbaum
  • BLUE LIGHT-ACTIVATED ION CHANNEL MOLECULES AND USES THEREOF
    Publication number: 20150223679
    Abstract: The invention, in some aspects relates to light-activated ion channel polypeptides and encoding nucleic acids and also relates in part to compositions comprising light-activated ion channel polypeptides and methods using light-activated ion channel polypeptides to alter cell activity and function.
    Type: Application
    Filed: February 6, 2015
    Publication date: August 13, 2015
    Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Nathan Klapoetke, Edward Boyden, Yongku Cho, Brian Y. Chow, Gane K.S. Wong, Adam E. Cohen, Daniel R. Hochbaum
  • BLOOD-BRAIN BARRIER TARGETING ANTIBODIES
    Publication number: 20080019984
    Abstract: This invention provides antibodies that bind brain endothelial cell receptors resulting in endocytosis/transcytosis of the receptor and bound ligands. In some embodiments, the ligand comprises the antibody in combination with a pharmaceutically active compound and the antibody directs delivery of the compound across the blood brain barrier (BBB). The invention also provides methods of identifying endothelial cell specific antibodies by panning the library against cultured cell monolayers. The invention further allows for identifying endothelial cell receptors that bind the antibody thereby providing target receptors against which to isolate further cognate ligands and their associated transport systems and by which to identify transcytosis transporters targeted by the antibodies.
    Type: Application
    Filed: June 7, 2007
    Publication date: January 24, 2008
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Eric Shusta, Xin Wang, Yongku Cho