Abstract: Disclosed herein are heterocyclic compounds, for example, according to the following formula and analogs thereof: that inhibit the activity of FLT3. Also described are specific covalent inhibitors of FLT3. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the FLT3 inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of proliferative diseases or conditions, including hematological malignancies and other diseases or conditions dependent on FLT3 activity.

Abstract: Disclosed is a secret-key provisioning (SKP) method and device based on an optical line terminal (OLT), which can generate an SKP queue according to key requests received; generate at least one secret-key according to the SKP queue; and store the at least one secret-key in key pools (KPs) of corresponding ONUS. A non-transitory computer-readable storage medium is also disclosed.

Abstract: The present disclosure discloses a treatment process and treatment system of enhanced up-flow multiphase wastewater oxidation. The treatment process includes the following steps: 1) the wastewater is fed into the up-flow multiphase wastewater oxidation system for oxidation treatment; 2) the wastewater is fed to the solid-liquid separation system for solid-liquid separation, the separated heterogeneous catalytic carrier (5) is fed back to the up-flow multiphase wastewater oxidation system, and the wastewater is fed to the neutralization and degassing system; 3) the wastewater is fed to the neutralization and degassing system to adjust a pH of the wastewater to 5.5-7.5, and then is degassed by stirring; 4) the wastewater is fed to the flocculation and sedimentation system for sludge-water separation, a supernatant is discharged, and an outward harmless treatment is performed after a pressure filtration of a sedimentary iron sludge.

Abstract: A ceramic component and a method for manufacturing a ceramic component are disclosed. In an embodiment a ceramic component includes a ceramic base body and at least one metallization located an outer surface of the ceramic base body, wherein the metallization contains lithium vanadium phosphate having the general chemical formula LixVy(PO4)z, copper and glass, wherein a is a proportion of copper, b is a proportion of lithium vanadium phosphate and c is a proportion of glass which is contained in the metallization, wherein the following applies: 40 wt. %?a?99 wt. %, 1 wt. %?b?30 wt. %, 0 wt. %?c?20 wt. %, wherein x is a proportion of lithium, y is a proportion of vanadium and z is a proportion of phosphate in lithium vanadium phosphate, and wherein the following applies: 0<x, 0<y, 0<z.

Abstract: The present disclosure provides a method for reducing the inhalation of microorganisms, a washable mask for reducing the inhalation of microorganisms, applications of the mask and a method for manufacturing the same. The method for reducing the inhalation of microorganisms includes the steps of: providing a mask with a breathing zone, the breathing zone being used for covering a breathing part of a user; arranging two or more magnets around the breathing zone of the mask, the magnets generating a three-dimensional magnetic field, so as to change the moving trajectories of charged microorganisms in gas to be inhaled thereby increasing the probability of the microorganisms being captured by the filtering material.

Abstract: In an embodiment an electrochemical cell includes a first electrode having a first surface area A1, a second electrode having a second surface area A2, an electrolyte arranged between the first electrode and the second electrode, wherein the electrochemical cell is configured to provide a first electrochemical half-cell reaction at the first electrode and provide a second electrochemical half-cell reaction at the second electrode, and wherein a surface area ratio A1/A2 is larger than a stoichiometric ratio of the first half-cell reaction and the second half-cell reaction.

Abstract: In an embodiment a sensor device for arrangement on a mouth-nose protection includes a sensor unit having at least one sensor element configured to detect individual breathing processes of a user when the mouth-nose protection with the sensor device is used by a user and an evaluation unit configured to count the breathing processes of the user depending on a detection signal provided by the sensor unit and provide an evaluation signal for a signaling unit depending on a determined number of breathing processes.

Abstract: Disclosed are a nitrogen-containing heterocyclic compound as shown in formula (I), or a stereoisomer, a solvate, a deuterated form, a pharmaceutically acceptable salt, or a cocrystal thereof or a pharmaceutical composition containing same, and the use thereof in the preparation of a drug for treating/preventing diseases mediated by autotaxin. Each group in formula (I) is as defined in the description.

Abstract: Amplifiers, amplification circuits, and phase shifters, for example, for flexibly adjusting an output phase to thereby meet a requirement of a constant phase on a link in a communications field, are provided. In one aspect, an amplifier includes first, second, and third MOS transistors. The first MOS transistor includes a gate separately coupled to a signal input end and a bias voltage input end, a source coupled to a power supply, and a drain separately coupled to sources of the second and third MOS transistors. A drain of the third MOS transistor is coupled to a ground, and a drain of the second MOS transistor is coupled to a signal output end. The bias voltage input end is configured to receive a bias voltage to adjust a phase difference between an input signal at the signal input end and an output signal at the signal output end.

Abstract: Embodiments of the present disclosure provide a method and device for deduplication. Specifically, the method may comprise obtaining a property of a file stream, the property of a file stream including a file type or a magic number identifying a format of a protocol or a file. The method further includes in response to receiving an I/O request for a data block of the file stream, assigning a deduplication level to the I/O request based on the property of the file stream. Moreover, the method further includes deduplicating the data block of the file stream based on the deduplication level assigned to the I/O request. In addition, a corresponding device and computer program product are provided.

Abstract: In an embodiment an assembly includes at least one surface mounted device (SMD) component, a metallic wiring configured to lead current from the at least one SMD component to an external circuit and at least one protection element is configured to cover all outer surface of the at least one SMD component and at least parts of the metallic wiring, wherein the assembly has a structure of a molded module, and wherein the at least one SMD component includes a rechargeable all solid-state battery.

Abstract: This application provides a variable gain amplifier and a phased array transceiver, to enable the variable gain amplifier to keep a phase constant when switching a gain, and to enable a gain step to be stable with a frequency. The variable gain amplifier includes an amplification circuit, configured to amplify an input signal; a control circuit, configured to control a gain of the amplification circuit by adjusting an output current of the amplification circuit; and an inductive load and an inductive adjustment circuit, where the inductive load is coupled to a signal output end of the amplification circuit, the inductive adjustment circuit and the inductive load are inductively coupled, and the inductive adjustment circuit is adjustable.

Abstract: In an embodiment a piezoelectric multilayer component includes a ceramic main body comprising a ceramic material, wherein a main component of the ceramic material has the general empirical formula (KXNa1-X)NbO3, where 0?x?1, wherein the ceramic material comprises at least two additives selected from a number of compounds respectively comprising at least one metal, wherein a metal of a first additive comprises at least K, Nb, Cu, Mn or Ta, and wherein a metal of a second additive comprises K, Nb or Ta.

Abstract: A ceramic material, a varistor and methods for forming a ceramic material and a varistor are disclosed. In an embodiment, a ceramic material includes ZnO as a main component and additives selected from the group consisting of an Al3+-containing solution, a Ba2+-containing solution, and at least one compound containing a metal element, wherein the metal element is selected from the group consisting of Bi, Sb, Co, Mn, Ni, Y, and Cr.

Abstract: A ceramic component and a method for manufacturing a ceramic component are disclosed. In an embodiment a ceramic component includes a ceramic base body and at least one metallization located an outer surface of the ceramic base body, wherein the metallization contains lithium vanadium phosphate having the general chemical formula LixVy(PO4)z, copper and glass, wherein a is a proportion of copper, b is a proportion of lithium vanadium phosphate and c is a proportion of glass which is contained in the metallization, wherein the following applies: 40 wt. %?a?99 wt. %, 1 wt. %?b?30 wt. %, 0 wt. %?c?20 wt. %, wherein x is a proportion of lithium, y is a proportion of vanadium and z is a proportion of phosphate in lithium vanadium phosphate, and wherein the following applies: 0<x, 0<y, 0<z.

Abstract: Embodiments of the present disclosure provide a method and device for deduplication. Specifically, the method may comprise obtaining a property of a file stream, the property of a file stream including a file type or a magic number identifying a format of a protocol or a file. The method further includes in response to receiving an I/O request for a data block of the file stream, assigning a deduplication level to the I/O request based on the property of the file stream. Moreover, the method further includes deduplicating the data block of the file stream based on the deduplication level assigned to the I/O request. In addition, a corresponding device and computer program product are provided.

Abstract: Amplifiers, amplification circuits, and phase shifters, for example, for flexibly adjusting an output phase to thereby meet a requirement of a constant phase on a link in a communications field, are provided. In one aspect, an amplifier includes first, second, and third MOS transistors. The first MOS transistor includes a gate separately coupled to a signal input end and a bias voltage input end, a source coupled to a power supply, and a drain separately coupled to sources of the second and third MOS transistors. A drain of the third MOS transistor is coupled to a ground, and a drain of the second MOS transistor is coupled to a signal output end. The bias voltage input end is configured to receive a bias voltage to adjust a phase difference between an input signal at the signal input end and an output signal at the signal output end.

Abstract: Embodiments of the present disclosure provide a method and device for deduplication. Specifically, the method may comprise obtaining a property of a file stream, the property of a file stream including a file type or a magic number identifying a format of a protocol or a file. The method further includes in response to receiving an I/O request for a data block of the file stream, assigning a deduplication level to the I/O request based on the property of the file stream. Moreover, the method further includes deduplicating the data block of the file stream based on the deduplication level assigned to the I/O request. In addition, a corresponding device and computer program product are provided.

Abstract: The present disclosure provides a method for reducing the inhalation of microorganisms, a washable mask for reducing the inhalation of microorganisms, applications of the mask and a method for manufacturing the same. The method for reducing the inhalation of microorganisms includes the steps of: providing a mask with a breathing zone, the breathing zone being used for covering a breathing part of a user; arranging two or more magnets around the breathing zone of the mask, the magnets generating a three-dimensional magnetic field, so as to change the moving trajectories of charged microorganisms in gas to be inhaled thereby increasing the probability of the microorganisms being captured by the filtering material.

Abstract: A ceramic material, a varistor and methods for forming a ceramic material and a varistor are disclosed. In an embodiment, a ceramic material includes ZnO as a main component and additives selected from the group consisting of an Al3+-containing solution, a Ba2+-containing solution, and at least one compound containing a metal element, wherein the metal element is selected from the group consisting of Bi, Sb, Co, Mn, Ni, Y, and Cr.