Patents by Inventor Yonglian Sun

Yonglian Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-C-C motif chemokine receptor 8 (CCR8) antibodies and methods of use
    Patent number: 12240910
    Abstract: The present disclosure provides anti-CCR8 antibodies, and compositions and methods of their preparation and use.
    Type: Grant
    Filed: July 13, 2022
    Date of Patent: March 4, 2025
    Assignee: Genentech, Inc.
    Inventors: Gautham Gampa, Iraj Hosseini, Mahrukh Huseni, James Thomas Koerber, Jian Mehr-Dean Payandeh, Sascha Rutz, Yonglian Sun, Cecilia P. C. Chiu, Teresita Arenzana Delfino
  • ANTI-KLK5 ANTIBODIES AND METHODS OF USE
    Publication number: 20250002609
    Abstract: The invention provides anti-KLK5 antibodies and methods of using the same.
    Type: Application
    Filed: June 11, 2024
    Publication date: January 2, 2025
    Applicant: Genentech, Inc.
    Inventors: Cecilia P.C. CHIU, Hilda Y. HERNANDEZ-BARRY, David B. IAEA, Moulay Hicham ALAOUI-ISMAILI, James T. KOERBER, Wei Yu LIN, Kelly LOYET, Yonglian SUN, Benjamin T. WALTERS, Jawahar SUDHAMSU
  • Anti-KLK5 antibodies and methods of use
    Patent number: 12037412
    Abstract: The invention provides anti-kallikrein-related peptidase 5 (KLK5) antibodies and methods of using the same.
    Type: Grant
    Filed: November 17, 2020
    Date of Patent: July 16, 2024
    Assignee: Genentech, Inc.
    Inventors: Cecilia P. C. Chiu, Hilda Y. Hernandez-Barry, David B. Iaea, Moulay Hicham Alaoui-Ismaili, James T. Koerber, Wei Yu Lin, Kelly Loyet, Yonglian Sun, Benjamin T. Walters, Jawahar Sudhamsu
  • METHODS FOR MAKING EXTRACELLULAR VESICLES AND USES THEREOF
    Publication number: 20230090177
    Abstract: The present disclosure relates to improved methods and compositions for making extracellular vesicles (EVs). The present disclosure also relates to novel EV-based ELISA assays and kits for performing such assays, as well as methods of producing antibodies to particular antigens using EVs comprising membrane-bound antigen.
    Type: Application
    Filed: November 28, 2022
    Publication date: March 23, 2023
    Applicant: GENENTECH, INC.
    Inventors: James Thomas Koerber, Yonglian Sun
  • ANTI-C-C MOTIF CHEMOKINE RECEPTOR 8 (CCR8) ANTIBODIES AND METHODS OF USE
    Publication number: 20230049152
    Abstract: The present disclosure provides anti-CCR8 antibodies, and compositions and methods of their preparation and use.
    Type: Application
    Filed: July 13, 2022
    Publication date: February 16, 2023
    Applicant: GENENTECH, INC.
    Inventors: Gautham Gampa, Iraj Hosseini, Mahrukh Huseni, James T. Koerber, Jian Mehr-Dean Payandeh, Sascha Rutz, Yonglian Sun, Cecilia P. C. Chiu, Teresita A. Delfino
  • METHODS FOR DETECTING AND QUANTIFYING MEMBRANE-ASSOCIATED PROTEINS
    Publication number: 20220099677
    Abstract: The present disclosure provides assays for the detection and/or quantification of membrane-associated proteins, e.g., circulating CD20 (cCD20), incorporating an extracellular vesicle-based calibrator comprising the membrane-associated tumor antigen as well as the use of such assays in the detection and treatment of hyperproliferative disorders.
    Type: Application
    Filed: September 8, 2021
    Publication date: March 31, 2022
    Applicant: GENENTECH, INC.
    Inventors: Vinita GUPTA, Ann Therese BRADY, James Thomas KOERBER, Xiangdan WANG, Minh Michael Nhu PHAN, Yonglian SUN
  • ANTI-KLK5 ANTIBODIES AND METHODS OF USE
    Publication number: 20210301032
    Abstract: The invention provides anti-KLK5 antibodies and methods of using the same.
    Type: Application
    Filed: November 17, 2020
    Publication date: September 30, 2021
    Applicant: Genentech, Inc.
    Inventors: Cecilia P.C. Chiu, Hilda Y. Hernandez-Barry, David B. Iaea, Moulay Hicham Alaoui-Ismaili, James T. Koerber, Wei Yu Lin, Kelly Loyet, Yonglian Sun, Benjamin T. Walters, Jawahar Sudhamsu
  • ANTI-KLK5 ANTIBODIES AND METHODS OF USE
    Publication number: 20200040103
    Abstract: The invention provides anti-KLK5 antibodies and methods of using the same.
    Type: Application
    Filed: March 13, 2019
    Publication date: February 6, 2020
    Applicant: Genentech, Inc.
    Inventors: Cecilia P. C. Chiu, Hilda Y. Hernandez-Barry, David B. Iaea, Moulay Hicham Alaoui-Ismaili, James T. Koerber, Wei Yu Lin, Kelly Loyet, Yonglian Sun, Benjamin T. Walters, Jawahar Sudhamsu
  • PILR ALPHA INTERACTIONS AND METHODS OF MODIFYING SAME
    Publication number: 20190276532
    Abstract: Described herein is a novel receptor-ligand interaction and agents that may modify and/or block the interaction. Methods, uses, reagents and kits for the modulation of ligand activities related to its interaction with the novel receptor are disclosed. Also disclosed are therapeutic uses of reagents in treating inflammation-related disorders.
    Type: Application
    Filed: November 5, 2018
    Publication date: September 12, 2019
    Inventors: Ali ZARRIN, Yonglian SUN
  • Methods of treating inflammatory diseases by administering anti-PILR-alpha antibody
    Patent number: 10160807
    Abstract: Described herein is a novel receptor-ligand interaction and agents that may modify and/or block the interaction. Methods, uses, reagents and kits for the modulation of ligand activities related to its interaction with the novel receptor are disclosed. Also disclosed are therapeutic uses of reagents in treating inflammation-related disorders.
    Type: Grant
    Filed: January 3, 2017
    Date of Patent: December 25, 2018
    Assignee: Genentech, Inc.
    Inventors: Ali Zarrin, Yonglian Sun
  • PILR ALPHA INTERACTIONS AND METHODS OF MODIFYING SAME
    Publication number: 20170137518
    Abstract: Described herein is a novel receptor-ligand interaction and agents that may modify and/or block the interaction. Methods, uses, reagents and kits for the modulation of ligand activities related to its interaction with the novel receptor are disclosed. Also disclosed are therapeutic uses of reagents in treating inflammation-related disorders.
    Type: Application
    Filed: January 3, 2017
    Publication date: May 18, 2017
    Inventors: Ali ZARRIN, Yonglian SUN
  • Methods for enhancing pathogen clearance by blocking its interaction with paired immunoglobulin-like type 2 receptor (PILR)?
    Patent number: 9556269
    Abstract: Described herein is a novel receptor-ligand interaction and agents that may modify and/or block the interaction. Methods, uses, reagents and kits for the modulation of ligand activities related to its interaction with the novel receptor are disclosed. Also disclosed are therapeutic uses of reagents in treating inflammation-related disorders.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: January 31, 2017
    Assignee: Genentech, Inc.
    Inventors: Ali Zarrin, Yonglian Sun
  • PILR ALPHA INTERACTIONS AND METHODS OF MODIFYING SAME
    Publication number: 20150203575
    Abstract: Described herein is a novel receptor-ligand interaction and agents that may modify and/or block the interaction. Methods, uses, reagents and kits for the modulation of ligand activities related to its interaction with the novel receptor are disclosed. Also disclosed are therapeutic uses of reagents in treating inflammation-related disorders.
    Type: Application
    Filed: January 16, 2015
    Publication date: July 23, 2015
    Inventors: Ali ZARRIN, Yonglian SUN
  • PILR alpha Interactions and Methods of Modifying Same
    Publication number: 20130344080
    Abstract: Described herein is a novel receptor-ligand interaction and agents that may modify and/or block the interaction. Methods, uses, reagents and kits for the modulation of ligand activities related to its interaction with the novel receptor are disclosed. Also disclosed are therapeutic uses of reagents in treating inflammation-related disorders.
    Type: Application
    Filed: June 19, 2013
    Publication date: December 26, 2013
    Applicant: GENENTECH, INC.
    Inventors: Ali Zarrin, Yonglian Sun