Patents by Inventor Yongling Xiao

Yongling Xiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELLS HAVING DISRUPTED EXPRESSION OF PROTEINS INVOLVED IN ADME AND TOXICOLOGY PROCESSES
    Publication number: 20160266093
    Abstract: The present invention provides cells comprising disrupted expression of at least one membrane transporter, drug metabolizing enzyme, xenobiotic sensor, or cellular stress response pathway protein. Also provided are methods for assessing the effect of an agent in the cells disclosed herein relative to comparable control cells.
    Type: Application
    Filed: January 15, 2016
    Publication date: September 15, 2016
    Inventors: Maureen Bourner, Timothy Brayman, Gary Davis, Michael D. Mitchell, David C. Thompson, Yongling Xiao
  • CELLS HAVING DISRUPTED EXPRESSION OF PROTEINS INVOLVED IN ADME AND TOXICOLOGY PROCESSES
    Publication number: 20130316391
    Abstract: The present invention provides cells comprising disrupted expression of at least one membrane transporter, drug metabolizing enzyme, xenobiotic sensor, or cellular stress response pathway protein. Also provided are methods for assessing the effect of an agent in the cells disclosed herein relative to comparable control cells.
    Type: Application
    Filed: December 28, 2011
    Publication date: November 28, 2013
    Applicant: Sigmaaldrich Co., LLC
    Inventors: Maureen Bourner, Timothy Brayman, Gary Davis, Michael D. Mitchell, David C. Thompson, Yongling Xiao
  • Canine peroxisome proliferator activated receptor gamma
    Publication number: 20030113815
    Abstract: This invention provides polynucleotides encoding canine peroxisome proliferator activated receptor gamma polypeptides, canine peroxisome proliferator activated receptor gamma polypeptides, vectors comprising polynucleotides encoding canine peroxisome proliferator activated receptor gamma polypeptides, transformed cells comprising polynucleotides encoding canine peroxisome proliferator activated receptor gamma polypeptides, antibodies which specifically binds to canine peroxisome proliferator activated receptor gamma polypeptides, microarrays comprising polynucleotides encoding canine peroxisome proliferator activated receptor gamma and therapeutic methods related thereto.
    Type: Application
    Filed: December 18, 2002
    Publication date: June 19, 2003
    Applicant: Pfizer Inc.
    Inventors: Karen L. Houseknecht, Pamela J. Steele, Yongling Xiao
  • Melanocortin-5 receptor sequences and uses thereof
    Publication number: 20030110518
    Abstract: The present invention relates to nucleic acids encoding functional canine melanocortin 5 receptors and their polypeptide products. The present invention further relates to screening assays to identify compounds that modulate the activity or expression of the melanocortin 5 receptor of the invention. The present invention also relates to methods and therapeutic compositions for the treatment of inappropriate food intake and skin disorders comprising administering to animals compounds that modulate the activity or expression of melanocortin 5 receptors.
    Type: Application
    Filed: September 25, 2002
    Publication date: June 12, 2003
    Inventors: Karen L. Houseknecht, Alan S. Robertson, Yongling Xiao