Patents by Inventor YONGLU CHEN

YONGLU CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230218721
    Abstract: An incretin analogue, a preparation method therefor, and the use thereof. The incretin analogue has a GLP-1R/GIPR/GCGR agonist activity, is a triple agonist, and can be used for lowering blood glucose, reducing fat and reducing weight.
    Type: Application
    Filed: February 26, 2021
    Publication date: July 13, 2023
    Applicants: ZHEJIANG DOER BIOLOGICS CO., LTD., ZHEJIANG HEZE PHARMACEUTICAL TECHNOLOGY CO., LTD.
    Inventors: YANSHAN HUANG, YONGLU CHEN, WENWEN DUAN, XIAOFANG WEN, YUANYUAN LIU, YUAN WANG, SHIMEI SHENG, YING LIU, SHENG NI, MINGYUE ZHU, CHEN FANG, PENG SUN
  • Publication number: 20220372150
    Abstract: The present disclosure provides a class of specific anti-PD-L1 single-domain antibodies that block PD-L1/PD-1 interaction, and humanized antibodies, fusion proteins, and pharmaceutical compositions prepared based on the single-domain antibodies, and use thereof.
    Type: Application
    Filed: July 6, 2020
    Publication date: November 24, 2022
    Applicant: ZHEJIANG DOER BIOLOGICS CO., LTD.
    Inventors: GAOFENG YAO, ZHENXING ZHOU, YONGLU CHEN, ZHIYU YANG, JIALI DONG, XIAOFANG WEN, YANSHAN HUANG
  • Patent number: 10815286
    Abstract: The invention provides fusion proteins for treating an intestinal disease, having a structure as follows: R-L-P, wherein R is a GLP-2 receptor agonist; L is a peptide linker; and P is a long-acting carrier protein. The fusion protein provided by the invention has significant bioactivities and in vitro stability.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: October 27, 2020
    Assignee: ZHEJIANG DOER BIOLOGICS CORPORATION
    Inventors: Xiaofang Wen, Yanshan Huang, Zhiyu Yang, Gaofeng Yao, Yonglu Chen, Xuelian Wang
  • Publication number: 20190241639
    Abstract: The invention provides fusion proteins for treating an intestinal disease, having a structure as follows: R-L-P, wherein R is a GLP-2 receptor agonist; L is a peptide linker; and P is a long-acting carrier protein. The fusion protein provided by the invention has significant bioactivities and in vitro stability.
    Type: Application
    Filed: October 18, 2017
    Publication date: August 8, 2019
    Applicant: ZHEJIANG DOER BIOLOGICS CORPORATION
    Inventors: XIAOFANG WEN, YANSHAN HUANG, ZHIYU YANG, GAOFENG YAO, YONGLU CHEN, XUELIAN WANG