Patents by Inventor Yongmei Liu

Yongmei Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240117467
    Abstract: Provided are an electrokinetic device and method for in-situ leaching of uranium, belonging to the technical field of in-situ leaching of uranium. The electrokinetic device for in-situ leaching of uranium includes an injection well, a pumping well, a positive electrode, a negative electrode, leaching solution, and a direct current power supply. Uranium ore is provided between the injection well and the pumping well, the negative electrode is arranged in the injection well, and the positive electrode is arranged in the pumping well. The leaching solution is injected from the injection well, flows through the uranium ore, and then is pumped from the pumping well for uranium extraction. The direct current power supply is respectively connected to the positive electrode and the negative electrode, and is configured to apply direct current between the positive electrode and the negative electrode to promote the pooling of uranium-carrying ions towards the pumping well.
    Type: Application
    Filed: April 13, 2023
    Publication date: April 11, 2024
    Inventors: Chunguang LI, Longcheng LIU, Chong ZHANG, Kaixuan TAN, Zhenzhong LIU, Yongmei LI, Shuo MENG, Wenji WANG, Qi LIU, Qianjin NIU
  • Publication number: 20240066048
    Abstract: Heparin compounds and synthetic heparin analogues having short acting anticoagulant activity are provided. Methods of synthesizing such heparin compounds, including chemoenzymatic pathways using sulfotransferase enzymes are provided. Methods of treating subjects in need of anticoagulant activity are provided.
    Type: Application
    Filed: July 17, 2023
    Publication date: February 29, 2024
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Jian Liu, Zhangjie Wang, Po-Hung Hsieh, Yongmei Xu
  • Patent number: 11798861
    Abstract: Embodiments may relate to a microelectronic package that includes a lid coupled with a package substrate such that a die is positioned between the lid and the package substrate. The lid may include a heating element that is to heat an area between the lid and the die. Other embodiments may be described or claimed.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: October 24, 2023
    Assignee: Intel Corporation
    Inventors: Peng Li, Kelly P. Lofgreen, Manish Dubey, Bamidele Daniel Falola, Ken Hackenberg, Shenavia S. Howell, Sergio Antonio Chan Arguedas, Yongmei Liu, Deepak Goyal
  • Patent number: 11791237
    Abstract: Microelectronic assemblies, and related devices and methods, are disclosed herein. For example, in some embodiments, a microelectronic assembly may include a package substrate having a first surface and an opposing second surface; a die having a first surface and an opposing second surface, wherein the first surface of the die is coupled to the second surface of the package substrate; a cooling apparatus thermally coupled to the second surface of the die; and a thermal interface material (TIM) between the second surface of the die and the cooling apparatus, wherein the TIM includes an indium alloy having a liquidus temperature equal to or greater than about 245 degrees Celsius.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: October 17, 2023
    Assignee: Intel Corporation
    Inventors: Peng Li, Sergio Antonio Chan Arguedas, Yongmei Liu, Deepak Goyal, Ken Hackenberg
  • Publication number: 20230250425
    Abstract: In the field of biomedical technology, a PIWI-interacting RNA piR-hsa-211106 is used to prepare a targeted therapeutic drug for inhibiting proliferation of lung adenocarcinoma cells. A mechanism is as follows: after the PIWI-interacting RNA piR-hsa-211106 is constructed into an agonist or a transformant, the agonist or the transformant inhibits a tricarboxylic acid cycle process by down-regulating an expression of a pyruvate carboxylase, inhibits an energy metabolism, promotes apoptosis of the lung adenocarcinoma cells, thus inhibits growth of the lung adenocarcinoma. The PIWI-interacting RNA piR-hsa-211106 directly acts on a target site and does not produce toxic and side effects and an off-target phenomenon. Large amounts of analysis and in-vivo and in-vitro experiments show that the PIWI-interacting RNA piR-hsa-211106 has high credibility and a remarkable treatment effect, and provides a new research direction for anti-tumor therapy of lung adenocarcinoma.
    Type: Application
    Filed: February 7, 2022
    Publication date: August 10, 2023
    Applicant: Qingdao University
    Inventors: Wenhua XU, Yongmei LIU, Yanhan DONG, Jinning GAO, Xiaodan HAO, Zibo WANG, Meng LI
  • Publication number: 20220047699
    Abstract: The present disclosure provides an adjuvant composition containing 0.2%-15% w/v carbomer, 0.1%-0.5% w/v lecithin, and 0.03%-0.2% w/v ginsenoside. The adjuvant composition of the present disclosure cannot only ensure the long-term clarification and/or stability of the vaccine, but also can effectively stimulate the inactivated antigens and subunit antigens therein to produce high-titer antibodies for immune protection. The inactivated vaccines or subunit vaccines prepared by the adjuvant composition of the present disclosure can be used as a diluent for freeze-dried live virus antigens and has no toxic effect on the live virus antigens.
    Type: Application
    Filed: April 17, 2019
    Publication date: February 17, 2022
    Inventors: Kegong Tian, Yongmei Liu, Xuke Zhang
  • Publication number: 20210013117
    Abstract: Embodiments may relate to a microelectronic package that includes a lid coupled with a package substrate such that a die is positioned between the lid and the package substrate. The lid may include a heating element that is to heat an area between the lid and the die. Other embodiments may be described or claimed.
    Type: Application
    Filed: July 8, 2019
    Publication date: January 14, 2021
    Applicant: Intel Corporation
    Inventors: Peng Li, Kelly P. Lofgreen, Manish Dubey, Bamidele Daniel Falola, Ken Hackenberg, Shenavia S. Howell, Sergio Antonio Chan Arguedas, Yongmei Liu, Deepak Goyal
  • Patent number: 10826292
    Abstract: An embodiment provides a multi-time-scale Digital/Analog (D/A) hybrid simulation system and simulation method therefor for a complex power distribution network and a computer storage medium, and is intended to solve existing problems about multi-time-scale modeling and simulation of the complex power distribution network and simulation accuracy and efficiency of the complex power distribution network.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: November 3, 2020
    Assignees: CHINA ELECTRIC POWER RESEARCH INSTITUTE CO. LTD., STATE GRID CORPORATION OF CHINA
    Inventors: Wanxing Sheng, Keyan Liu, Xiaoli Meng, Weijie Dong, Yajie Li, Xueshun Ye, Yongmei Liu, Yinglong Diao, Dongli Jia, Lijuan Hu, Kaiyuan He
  • Publication number: 20200006192
    Abstract: Microelectronic assemblies, and related devices and methods, are disclosed herein. For example, in some embodiments, a microelectronic assembly may include a package substrate having a first surface and an opposing second surface; a die having a first surface and an opposing second surface, wherein the first surface of the die is coupled to the second surface of the package substrate; a cooling apparatus thermally coupled to the second surface of the die; and a thermal interface material (TIM) between the second surface of the die and the cooling apparatus, wherein the TIM includes an indium alloy having a liquidus temperature equal to or greater than about 245 degrees Celsius.
    Type: Application
    Filed: June 27, 2018
    Publication date: January 2, 2020
    Applicant: Intel Corporation
    Inventors: Peng Li, Sergio Antonio Chan Arguedas, Yongmei Liu, Deepak Goyal, Ken Hackenberg
  • Publication number: 20190067939
    Abstract: An embodiment provides a multi-time-scale Digital/Analog (D/A) hybrid simulation system and simulation method therefor for a complex power distribution network and a computer storage medium, and is intended to solve existing problems about multi-time-scale modeling and simulation of the complex power distribution network and simulation accuracy and efficiency of the complex power distribution network.
    Type: Application
    Filed: June 28, 2017
    Publication date: February 28, 2019
    Inventors: Wanxing Sheng, Keyan Liu, Xiaoli Meng, Weijie Dong, Yajie Li, Xueshun Ye, Yongmei Liu, Yinglong Diao, Dongli Jia, Lijuan Hu, Kaiyuan He
  • Publication number: 20170176173
    Abstract: Described herein are devices and techniques for measuring a thickness of a surface layer. A device can include a detector, a processor, and a memory. The detector can be arranged to receive reflected light from a surface of a sample. The processor can be in electrical communication with the detector. The memory can store instructions that, when executed by the processor, can cause the processor to perform operations. The operations can include receiving optical data from the detector, determining a polarization change of the reflected light, the polarization change being a function of the optical data, and determining a thickness of the surface layer using the polarization change and the wavelength of the incident light. The optical data can include information regarding the phase difference of the reflected light and the incident light. Also described are other embodiments.
    Type: Application
    Filed: December 17, 2015
    Publication date: June 22, 2017
    Inventors: Yanmei Song, Yongmei Liu, Deepak Goyal, Donglai David Lu, Marcel A. Wall
  • Publication number: 20080005886
    Abstract: A method and machine may operate to fabricate a unitary, substantially uniformly distributed transfer material that can be coupled to a carrier material.
    Type: Application
    Filed: September 18, 2007
    Publication date: January 10, 2008
    Inventors: Rajen Dias, Yongmei Liu
  • Patent number: 7317258
    Abstract: An apparatus and system, as well as fabrication methods therefor, may include a unitary, substantially uniformly distributed transfer material coupled to a carrier material.
    Type: Grant
    Filed: March 6, 2006
    Date of Patent: January 8, 2008
    Assignee: Intel Corporation
    Inventors: Rajen C. Dias, Yongmei Liu
  • Publication number: 20060146501
    Abstract: An apparatus and system, as well as fabrication methods therefor, may include a unitary, substantially uniformly distributed transfer material coupled to a carrier material.
    Type: Application
    Filed: March 6, 2006
    Publication date: July 6, 2006
    Inventors: Rajen Dias, Yongmei Liu
  • Patent number: 7042729
    Abstract: An apparatus and system, as well as fabrication methods therefor, may include a unitary, substantially uniformly distributed transfer material coupled to a carrier material.
    Type: Grant
    Filed: June 24, 2003
    Date of Patent: May 9, 2006
    Assignee: Intel Corporation
    Inventors: Rajen C. Dias, Yongmei Liu
  • Publication number: 20060068521
    Abstract: A method of fabricating a microelectronic package, a package fabricated according to the method, and a system including the package. The method comprises: providing a substrate and a die each having pre-solder bumps thereon; placing a patterned underfill film onto the substrate, the film having a filler therein, being substantially free of added flux and further defining a pattern of through-holes disposed such that corresponding pre-solder bumps of the substrate are exposed through the through-holes after placing the film; placing the die onto the substrate such that pre-solder bumps on the die contact corresponding pre-solder bumps on the substrate; forming solder joints from pre-solder bumps contacting one another; and after forming solder joints, solidifying the film to form the package.
    Type: Application
    Filed: September 29, 2004
    Publication date: March 30, 2006
    Inventors: Song-Hua Shi, Yongmei Liu
  • Patent number: 6907415
    Abstract: A method for finding rules and exceptions from a database uses four stages programmed into a computer, wherein the four stages include an adaptive stage for creating in accordance with a user's previously inputted specifications, a parameter file of rules and exceptions finding conditions in accordance with the user's specifications, with the file being displayed to the user; a data model stage for analyzing the parameters from the parameter file, and retrieving data from one or more databases in accordance with the parameters; a problem formulator stage for transforming the retrieved data into a formalized data structure compatible with the parameters, and creating a catalog of possible attributes; and a solving stage for generating rules and exceptions from the formalized data by using the parameters and the catalog, and sending the result to the adaptive stage.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: June 14, 2005
    Inventors: Masao Okada, Yongmei Liu
  • Publication number: 20040264138
    Abstract: An apparatus and system, as well as fabrication methods therefor, may include a unitary, substantially uniformly distributed transfer material coupled to a carrier material.
    Type: Application
    Filed: June 24, 2003
    Publication date: December 30, 2004
    Applicant: Intel Corporation
    Inventors: Rajen C. Dias, Yongmei Liu
  • Publication number: 20040015466
    Abstract: A method for finding rules and exceptions from a database uses four stages programmed into a computer, wherein the four stages include an adaptive stage for creating in accordance with a user's previously inputted specifications, a parameter file of rules and exceptions finding conditions in accordance with the user's specifications, with the file being displayed to the user; a data model stage for analyzing the parameters from the parameter file, and retrieving data from one or more databases in accordance with the parameters; a problem formulator stage for transforming the retrieved data into a formalized data structure compatible with the parameters, and creating a catalog of possible attributes; and a solving stage for generating rules and exceptions from the formalized data by using the parameters and the catalog, and sending the result to the adaptive stage.
    Type: Application
    Filed: May 15, 2001
    Publication date: January 22, 2004
    Inventors: Masao Okada, Yongmei Liu