Abstract: Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject.

Abstract: An outdoor unit of an air conditioner includes an outdoor-unit main control circuit, a power supply, a power supply control circuit, and an outdoor-unit communication circuit. The power supply control circuit is disposed in a loop of a power supply line for supplying power to the power supply, and is configured to control the power supply line to supply power to the power supply by controlling on/off of the loop; and the power supply is configured to supply power to the outdoor-unit main control circuit and the outdoor-unit communication circuit after receiving the power supplied from the power supply line.

Abstract: A multi-link wheel base includes a main body composed of a plurality of links connected in series and wheels provided on the main body, and the wheels are provided on the link assembly the link assembly includes an intermediate link and an end link, wherein both sides of the intermediate link are provided with a rotational connection position, one side of the end link is provided with a rotational connection position, and the rotational connection positions on the adjacent link assemblies are rotationally connected by means of a connecting device.

Abstract: A multi-link wheel base includes a main body composed of a plurality of links connected in series and wheels provided on the main body, and the wheels are provided on the link assembly the link assembly includes an intermediate link and an end link, wherein both sides of the intermediate link are provided with a rotational connection position, one side of the end link is provided with a rotational connection position, and the rotational connection positions on the adjacent link assemblies are rotationally connected by means of a connecting device.

Abstract: The present invention discloses a flat ground cross-country type roller skate comprising a skate body (1), wherein a wheel assembly at a lower part of the skate body, wherein the wheel assembly comprises a mounting seat (6) used to mount the skate body (1) and a hoisting mechanism disposed on the mounting seat (6). There are at least three wheel assemblies disposed on the hoisting mechanism, and each wheel assembly can hoist independently under the action of the hoisting mechanism. Thus, the wheel assemblies of the roller skate can be hoisted independently so as to adapt to various roads with uneven surface.

Abstract: The present invention discloses a flat ground cross-country type roller skate comprising a skate body (1), wherein a wheel assembly at a lower part of the skate body, wherein the wheel assembly comprises a mourning seat (6) used to mount the skate body (1) and a hoisting mechanism disposed on the mounting seat (6). There are at least three wheel assemblies disposed on the hoisting mechanism, and each wheel assembly can hoist independently under the action of the hoisting mechanism. Thus, the wheel assemblies of the roller skate can be hoisted independently so as to adapt to various roads with uneven surface.

Abstract: A method of reducing authentication requirements for data transmissions includes receiving a request for a data transmission between a sender and a receiver. The request includes an amount of data associated with the data transmission. An overall confidence level is determined between the receiver and the sender. A data transmission protection mechanism is selected based on the overall confidence level between the receiver and the sender. The data transmission is performed based on the selected data transmission protection mechanism.

Abstract: Transdermal delivery peptides for the treatment of skin diseases and/or facilitation or enhancement of transdermal delivery of pharmaceutically active agents are provided. Compositions comprising the transdermal delivery peptides and methods of therapeutic use, including the improvement of transdermal delivery of drugs or other pharmaceutically active agents, are also disclosed. Nucleic acids, expression vectors, and methods of their use, which encode the transdermal delivery peptides are disclosed. Methods are also provided for in vivo phage display for identifying further peptides with enhanced transdermal delivery capability.

Abstract: Transdermal delivery peptides for the treatment of skin diseases and/or facilitation or enhancement of transdermal delivery of pharmaceutically active agents are provided. Compositions comprising the transdermal delivery peptides and methods of therapeutic use, including the improvement of transdermal delivery of drugs or other pharmaceutically active agents, are also disclosed. Nucleic acids, expression vectors, and methods of their use, which encode the transdermal delivery peptides are disclosed. Methods are also provided for in vivo phage display for identifying further peptides with enhanced transdermal delivery capability.