Patents by Inventor Yongqiang Liu

Yongqiang Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240122001
    Abstract: A display includes a polygonal display region and a plurality of non-display portions. The non-display portions are coupled to side edges of the display region in a one-to-one correspondence. At least two of the non-display portions are bent to a back side of the display region. When the non-display portions bent to the back side include adjacent non-display portions, there is an opening between two adjacent non-display portions.
    Type: Application
    Filed: August 21, 2020
    Publication date: April 11, 2024
    Inventors: Lei Wang, Liangyu Pan, Yuan Yan, Haiyan Li, Yongqiang Pang, Yang Liu
  • Publication number: 20240098037
    Abstract: Provided is a multimedia data stream processing method, an electronic device and a storage medium, relating to the field of artificial intelligence, and specifically, to the technical fields of cloud computing, media cloud technology, and the like, which may be applied to scenes such as smart cloud. The multimedia data stream processing method includes: allocating a plurality of sub-streams of a multimedia data stream to a plurality of edge resource nodes, where the multimedia data stream is segmented into a plurality of slices and each of the plurality of sub-streams includes a part of the plurality of slices of the multimedia data stream; and scheduling the plurality of edge resource nodes to provide the plurality of sub-streams of the multimedia data stream for a terminal device.
    Type: Application
    Filed: January 23, 2023
    Publication date: March 21, 2024
    Inventors: Yugang Ke, Chongming Gu, Zhoufeng Wang, Junwen Gao, Weihui Liu, Minglu Li, Feifei Cao, Yongqiang Wu, Xiaoen Zhu
  • Publication number: 20240086719
    Abstract: A computing system including a plurality of processing devices configured to execute a Mixture-of-Experts (MoE) layer. The processing devices are configured to execute the MoE layer at least in part by receiving an input tensor including input tokens. Executing the MoE layer further includes computing a gating function output vector based on the input tensor and computing a sparse encoding of the input tensor and the gating function output vector. The sparse encoding indicates one or more destination expert sub-models. Executing the MoE layer further includes dispatching the input tensor for processing at the one or more destination expert sub-models, and further includes computing an expert output tensor. Executing the MoE layer further includes computing an MoE layer output at least in part by computing a sparse decoding of the expert output tensor. Executing the MoE layer further includes conveying the MoE layer output to an additional computing process.
    Type: Application
    Filed: May 16, 2023
    Publication date: March 14, 2024
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Yifan XIONG, Changho HWANG, Wei CUI, Ziyue YANG, Ze LIU, Han HU, Zilong WANG, Rafael Omar SALAS, Jithin JOSE, Prabhat RAM, Ho-Yuen CHAU, Peng CHENG, Fan YANG, Mao YANG, Yongqiang XIONG
  • Patent number: 11878078
    Abstract: The present invention relates to the technical field of medicine and relates to an instant release pharmaceutical preparation of an anticoagulant and a preparation method therefor. The instant release pharmaceutical preparation of an anticoagulant comprises a vicagrel compound or a pharmaceutically acceptable form thereof, the preparation is a tablet or a capsule, the vicagrel or the pharmaceutically acceptable form thereof is provided at a suitable particle size, and the D90 thereof <50 ?m. With regard to the drug-containing particles obtained by the present invention, a pharmaceutical preparation formed therefrom exhibits rapid release characteristics in an in vitro dissolution test and exhibits considerable advantages in pharmacokinetics in vivo, showing a greater degree (AUC) and rate (Cmax) of drug absorption.
    Type: Grant
    Filed: October 20, 2022
    Date of Patent: January 23, 2024
    Assignee: Jiangsu Vcare PharmaTech Co., Ltd.
    Inventors: Yanlei Zhao, Jianjun Zhang, Xuefang Liu, Yuan Gao, Hongbin Sun, Yanchun Gong, Yongqiang Liu
  • Patent number: 11858912
    Abstract: The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X, D, R1 to R4, and R6 to R10 are as described herein. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.
    Type: Grant
    Filed: July 14, 2022
    Date of Patent: January 2, 2024
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Mathis Braendlin, Sandra Marie Joseph Grall-Ulsemer, Xingchun Han, Christian Lerner, Mingming Li, Yongqiang Liu, Sébastien Schmitt, Jianhua Wang, Yongguang Wang, Min Wang, Song Yang, Chengang Zhou
  • Publication number: 20230373978
    Abstract: The invention provides novel heteroaryl-substituted imidazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein A and R1 to R6 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.
    Type: Application
    Filed: August 1, 2023
    Publication date: November 23, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Christian LERNER, Mingming LI, Yongqiang LIU, Jianhua WANG, Min WANG, Yongguang WANG, Song YANG, Chengang ZHOU
  • Publication number: 20230365634
    Abstract: The present invention discloses a protein regulating nitrogen-use efficiency and yield of a plant and the use thereof. The present invention obtains a transgenic OsTCP19 rice and a rice OsTCP19 mutant by means of a transgenic technique and a CRISPR-Cas9 technique, respectively. Experiments have shown that compared with wild-type rice, the transgenic OsTCP19 rice has a reduced tiller number and a decreased nitrogen response ability, whereas compared with the wild-type rice, the rice OsTCP19 mutant has an increased tiller number. This indicates that the OsTCP19 protein has the function of regulating the plant yield and nitrogen-use efficiency, thus laying the foundation for cultivating varieties with a high yield and a high nitrogen-use efficiency.
    Type: Application
    Filed: September 14, 2021
    Publication date: November 16, 2023
    Inventors: Chengcai CHU, Yongqiang LIU, Bin HU, Hongru WANG
  • Publication number: 20230295123
    Abstract: The invention provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1-R7 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.
    Type: Application
    Filed: February 28, 2023
    Publication date: September 21, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Christian LERNER, Mingming LI, Yongqiang LIU, Sébastien SCHMITT, Jianhua WANG, Min WANG, Yongguang WANG, Song YANG, Chengang ZHOU
  • Publication number: 20230257354
    Abstract: The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R9 and p are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.
    Type: Application
    Filed: March 6, 2023
    Publication date: August 17, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Zhanling CHENG, Christian LERNER, Yongqiang LIU, Matthias NETTEKOVEN, Philippe PFLIEGER, Bernd PUELLMANN, Jianhua WANG, Min WANG, Yongguang WANG, Song YANG, Chengang ZHOU
  • Publication number: 20230234939
    Abstract: The invention provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein A and R1-R7 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.
    Type: Application
    Filed: February 27, 2023
    Publication date: July 27, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Sandra Marie Joseph GRALL-ULSEMER, Wolfgang GUBA, Christian LERNER, Mingming LI, Yongqiang LIU, Markus RUDOLPH, Sébastien SCHMITT, Lorenz URNER, Yongguang WANG, Min WANG, Jianhua WANG, Song YANG, Chengang ZHOU, Patrizio MATTEI
  • Publication number: 20230218005
    Abstract: This application provides an e-cigarette vaporizer and an e-cigarette. The e-cigarette vaporizer includes an outer housing including an open end and an end cap arranged at the open end, where a liquid storage cavity and a sealing base configured to seal the liquid storage cavity are provided in the outer housing; a sealing ring is arranged between the end cap and the outer housing; a vaporization cavity is provided between the sealing ring and the sealing base, and the liquid substrate is vaporized in the vaporization cavity to generate aerosol released to the vaporization cavity; and a plurality of liquid storage grooves configured to adsorb and hold aerosol condensate are provided in the vaporization cavity. The e-cigarette vaporizer uses the liquid storage groove for absorbing the condensate through the capillary action, and prevents the condensate from being taken out along with inhaling airflow during inhaling.
    Type: Application
    Filed: June 10, 2021
    Publication date: July 13, 2023
    Inventors: YONGQIANG LIU, LINHAI LU, ZHONGLI XU, YONGHAI LI
  • Publication number: 20230203047
    Abstract: The invention provides novel imidazopyrazine derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X1 to X4, R1 to R5, R8 to R10, A, and L1 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.
    Type: Application
    Filed: November 29, 2022
    Publication date: June 29, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Christian LERNER, Yongqiang LIU, Song YANG, Chengang ZHOU
  • Publication number: 20230141600
    Abstract: The invention provides novel imidazopyrazine derivatives having the general formula (I), wherein Rx and R3 to R5 are as described herein: or pharmaceutically acceptable salts thereof. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.
    Type: Application
    Filed: December 6, 2022
    Publication date: May 11, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Zhanling CHENG, Christian KRAMER, Christian LERNER, Yongqiang LIU, Matthias NETTEKOVEN, Philippe PFLIEGER, Sébastien SCHMITT, Theodor STOLL, Jianhua WANG, Yongguang WANG, Song YANG, Chengang ZHOU
  • Publication number: 20230133845
    Abstract: The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X, D, R1 to R4, and R6 to R10 are as described herein. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.
    Type: Application
    Filed: July 14, 2022
    Publication date: May 4, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Mathis BRAENDLIN, Sandra Marie Joseph GRALL-ULSEMER, Xingchun HAN, Christian LERNER, Mingming LI, Yongqiang LIU, Sébastien SCHMITT, Jianhua WANG, Yongguang WANG, Min WANG, Song YANG, Chengang ZHOU
  • Publication number: 20230124923
    Abstract: The present invention relates to the technical field of medicine and relates to an instant release pharmaceutical preparation of an anticoagulant and a preparation method therefor. The instant release pharmaceutical preparation of an anticoagulant comprises a vicagrel compound or a pharmaceutically acceptable form thereof, the preparation is a tablet or a capsule, the vicagrel or the pharmaceutically acceptable form thereof is provided at a suitable particle size, and the D90 thereof <50 ?m. With regard to the drug-containing particles obtained by the present invention, a pharmaceutical preparation formed therefrom exhibits rapid release characteristics in an in vitro dissolution test and exhibits considerable advantages in pharmacokinetics in vivo, showing a greater degree (AUC) and rate (Cmax) of drug absorption.
    Type: Application
    Filed: October 20, 2022
    Publication date: April 20, 2023
    Applicant: Jiangsu Vcare PharmaTech Co., Ltd.
    Inventors: Yanlei Zhao, Jianjun Zhang, Xuefang Liu, Yuan Gao, Hongbin Sun, Yanchun Gong, Yongqiang Liu
  • Patent number: 11597729
    Abstract: Disclosed in the present invention are a pyrazolo [1,5-a]pyrimidine derivative having a structure of formula (I), a pharmaceutical composition comprising the compound of formula (I), and use of the compound in the preparation of a medicament for preventing or treating diseases associated with tropomyosin receptor kinases, in particular for preventing or treating cancers associated with tropomyosin receptor kinases. Each substituent in formula (I) has the same definition as that in the description.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: March 7, 2023
    Assignee: JIANGSU VCARE PHARMATECH CO., LTD.
    Inventors: Yong Wu, Wenbin Zhou, Yanchun Gong, Yaoxiang Yue, Jie Deng, Yongqiang Liu
  • Publication number: 20220396565
    Abstract: Provided are novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R4, m, n, and p are as described herein. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.
    Type: Application
    Filed: July 20, 2022
    Publication date: December 15, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Zhanling CHENG, Xingchun HAN, Christian KRAMER, Christian LERNER, Yongqiang LIU, Matthias NETTEKOVEN, Philippe PFLIEGER, Bernd PUELLMANN, Jianhua WANG, Lisha WANG, Min WANG, Yongguang WANG, Song YANG, Chengang ZHOU
  • Patent number: 11478432
    Abstract: The present invention relates to the technical field of medicine and relates to an instant release pharmaceutical preparation of an anticoagulant and a preparation method therefor. The instant release pharmaceutical preparation of an anticoagulant comprises a vicagrel compound or a pharmaceutically acceptable form thereof, the preparation is a tablet or a capsule, the vicagrel or the pharmaceutically acceptable form thereof is provided at a suitable particle size, and the D90 thereof <50 ?m. With regard to the drug-containing particles obtained by the present invention, a pharmaceutical preparation formed therefrom exhibits rapid release characteristics in an in vitro dissolution test and exhibits considerable advantages in pharmacokinetics in vivo, showing a greater degree (AUC) and rate (Cmax) of drug absorption.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: October 25, 2022
    Assignee: Jiangsu Vcare Pharma Tech Co., Ltd.
    Inventors: Yanlei Zhao, Jianjun Zhang, Xuefang Liu, Yuan Gao, Hongbin Sun, Yanchun Gong, Yongqiang Liu
  • Publication number: 20220177467
    Abstract: A 7-azaindole derivative having the structure of formula (I), a pharmaceutical composition containing the compound of formula (I), and uses of the compound in preparing a medicament for preventing or treating Janus kinase (JAK) family-related diseases, specifically, uses in preventing or treating inflammatory diseases related to protein tyrosine kinase.
    Type: Application
    Filed: January 19, 2020
    Publication date: June 9, 2022
    Inventors: Yong Wu, Yanchun Gong, Wenbin Zhou, Daan Qin, Ya Zhang, Yongqiang Liu
  • Publication number: 20210323981
    Abstract: The present invention relates to novel compounds of formula (I), wherein R1, R2, R3, R4, R5 and R6 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: May 20, 2021
    Publication date: October 21, 2021
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Hong SHEN, Xuefei TAN, Chengang ZHOU, Mingwei ZHOU, Yimin HU, Houguang SHI, Fabian DEY, Yongqiang LIU, Xiao DING