Abstract: Disclosed are a vibration sound device for an electronic product and the electronic product. The vibration sound device comprises a first housing, a magnetic assembly, a coil assembly and a second housing. The first housing includes a cavity and is opened at one side thereof. An interaction force is generated between the magnetic assembly in the first housing and the coil assembly on the second housing to drive the vibration sound device to vibrate and sound. According to the present disclosure, the magnetic assembly and the coil assembly are configured into a nested form, so that the overall height of the vibration sound device is reduced, the space utilization rate and the assembly precision are improved, and enough utilization space is provided for an electronic device.

Abstract: A vibration exciter for an electronic product comprises a first vibration assembly comprising a first casing (101) and a magnetic circuit assembly below thereof; a second vibration assembly comprising a second casing (105) and at least two groups of coils (102) above thereof and on two sides of the magnetic circuit assembly; the magnetic circuit assembly comprises a central magnet (103b) and at least two side magnets (103a, 103b) in a vibration direction, the magnetizing directions of the two side magnets are parallel to an axial direction of the coils, directions of magnetic poles are opposite; the central magnet comprises at least two groups of magnets (103b, 1032b) in a direction perpendicular to the vibration direction, the magnetizing directions of the at least two groups of magnets are parallel to the vibration direction the directions of the magnetic poles are opposite. The electronic product is also disclosed.

Abstract: A digital detection method and system for predicting drug resistance of transgenic maize are disclosed. The method includes acquiring an RGB image, three-dimensional point cloud data and chlorophyll relative content of a maize plant after medicament spraying at a current moment; calculating a pixel ratio and morphological feature according to the RGB image and three-dimensional point cloud data; inputting a detection parameter of the maize plant at the current moment into a series model to predict the detection parameter of the maize plant at a next moment to obtain a graph of change in the detection parameter in a next period; estimating a drug resistance characteristic according to the graph of the change in the detection parameter of the maize plant; and inputting the detection parameter of the maize plant at the current moment into a parallel model to predict the variety of the maize plant.

Abstract: A compound of formula (I) having the activity of inhibiting HPK1 kinase and a pharmaceutical composition comprising the compound. Also provided are the use of the compound in the prevention and/or treatment of cancers, tumors, inflammatory diseases, autoimmune diseases or immune-mediated diseases.

Abstract: The present disclosure provides a fluorescent probe for detection of jasmonic acid (JA) and a preparation method thereof, and a detection method of JA, belonging to the technical field of component detection, The fluorescent probe for detection of JA includes a cobalt-based metal-organic framework (MOF) material, and aminated carbon quantum dots (CQDs) and a molecular imprinting polymer (MIP) that are distributed on a surface of the Co-MOF material; where the MIP has a molecular imprinting (MI) of the JA. In the present disclosure, the NCQDs are distributed on the surface of the Co-MOF material, and cobalt ions can undergo a coordination reaction with amino groups to change a charge distribution on a surface of the NCQD; meanwhile, the Co-MOF material can also avoid aggregation of the NCQDs to improve a detection stability.

Abstract: Provided are a compound of Formula (I) and a pharmaceutical composition thereof, as well as a method for using the compounds of Formula (I) to prevent and/or treat immune-related disorders.

Abstract: The present disclosure provides a ratiometric fluorescent probe, a preparation method thereof, and an application in detection of hydrogen peroxide. In the present disclosure, MoOx QDs (nanoenzymes) and Co/Zn-MOFs both have catalytic activity, and the large specific surface area and porous structure of Co/Zn-MOFs can provide more binding sites for the contact between nanoenzymes and substrates. Moreover, Co/Zn-MOFs have high catalytic activity similar to natural enzymes. When nanoenzymes with fluorescent properties encounter Co/Zn-MOFs with similar catalytic activity, they will collide with a spark of “synergy catalysis”, and the fusion of the two plays a role of synergy catalysis; in addition, the uniform cavity of Co/Zn-MOFs can provide “hosts” for nanoenzymes, and Co/Zn-MOFs provide “anchors” for MoOx QDs, avoiding the aggregation of MoOx QDs and enhancing the stability of the probe.

Abstract: A compound represented by formula (I) and a pharmaceutical composition thereof. The compound represented by formula (I) may be used as an adenosine receptor inhibitor, especially as an A2A and/or A2B inhibitor, for example, the compound may be used to prevent or treat diseases related to A2A and/or A2B activity or expression.

Abstract: A compound represented by formula (I) and a pharmaceutical composition thereof. The compound represented by formula (I) can be used as an adenosine receptor inhibitor, in particular, A2A and/or A2B inhibitors, for example, can be used for preventing or treating diseases related to A2A and/or A2B activity or expression level.

Abstract: A digital detection method and system for predicting drug resistance of transgenic maize are disclosed. The method includes acquiring an RGB image, three-dimensional point cloud data and chlorophyll relative content of a maize plant after medicament spraying at a current moment; calculating a pixel ratio and morphological feature according to the RGB image and three-dimensional point cloud data; inputting a detection parameter of the maize plant at the current moment into a series model to predict the detection parameter of the maize plant at a next moment to obtain a graph of change in the detection parameter in a next period; estimating a drug resistance characteristic according to the graph of the change in the detection parameter of the maize plant; and inputting the detection parameter of the maize plant at the current moment into a parallel model to predict the variety of the maize plant.

Abstract: Fluorescent test paper for detecting mercury ions is firstly prepared, the fluorescent test paper including a fluorescence development area and a standard fluorescent colorimetric card. With reference to an excited color corresponding to a reference channel in the standard colorimetric card, the color corresponding to a carbon quantum dots distribution area on the fluorescent test paper is observed to check the fluorescence detection environment during detection with the fluorescent test paper. In colorimetric detection of the content of mercury ions, the concentration of Hg2+ is detected based on an excited color, in the standard colorimetric card, that corresponds to a standard mercury ion sample and is closest to a color signal in a copper nanoclusters distribution area on the fluorescent test paper.

Abstract: The present invention disclosed a method for preparing a thickener for tight oil and gas reservoir, which relieves damages. The technical solution includes the following steps: putting a three-flask in ice; adding perfluoroalkyl alcohol, P-toluenesulfonyl chloride and pyridine; reacting for 3 h at 0-20° C.; adding filter paper; ultrasonic dispersing for 1 h; removing the filter paper; washing the solution for 3-5 times by adding dilute hydrochloric acid to collect the intermediate product (I); adding 1,3-dihydroxy-propane-2-tert-butyl carbamate and the intermediate product (I) in another three-flask; adding potassium carbonate and N,N-dimethylformamide; reacting for 4 h at 40° C. to collect the intermediate product (II); adding trifluoroacetic acid and methylene chloride into the intermediate product (II); reacting at 45° C. for 2 h; extracting and vacuum drying; and adding 1,6-hexamethylene diisocyanate; reacting for 2 h to collect the final product (III).

Abstract: Fluorescent test paper for detecting mercury ions is firstly prepared, the fluorescent test paper including a fluorescence development area and a standard fluorescent colorimetric card. With reference to an excited color corresponding to a reference channel in the standard colorimetric card, the color corresponding to a carbon quantum dots distribution area on the fluorescent test paper is observed to check the fluorescence detection environment during detection with the fluorescent test paper. In colorimetric detection of the content of mercury ions, the concentration of Hg2+ is detected based on an excited color, in the standard colorimetric card, that corresponds to a standard mercury ion sample and is closest to a color signal in a copper nanoclusters distribution area on the fluorescent test paper.

Abstract: The present invention disclosed a method for prparing a thickener for tight oil and gas reservoir, which relieves damages. The technical solution includes the following steps: putting a three-flask in ice; adding perfluoroalkyl alcohol, P-toluenesulfonyl chloride and pyridine; reacting for 3 h at 0-20° C.; adding filter paper; ultrasonic dispersing for 1 h; removing the filter paper; washing the solution for 3-5 times by adding dilute hydrochloric acid to collect the intermediate product (I); adding 1,3-dihydroxy-propane-2-tert-butyl carbamate and the intermediate product (I) in another three-flask; adding potassium carbonate and N,N-dimethylformamide; reacting for 4h at 40° C. to collect the intermediate product (II); adding trifluoroacetic acid and methylene chloride into the intermediate product (II); reacting at 45° C. for 2 h; extracting and vacuum drying; and adding 1,6-hexamethylene diisocyanate; reacting for 2 h to collect the final product (III).

Abstract: A system and methods for electro-optical modulation are presented. A first optical signal and a second optical signal are optically coupled to produce a local oscillator signal propagated in two signal paths. The local oscillator signal in the first signal path and the second signal path is electro-optically phase modulated with a radio frequency electrical signal to produce a first phase modulated optical signal and a second phase modulated optical signal respectively. The first phase modulated optical signal and the second phase modulated optical signal are optically coupled to produce an intensity modulated signal comprising an RF frequency of the radio frequency electrical signal frequency mixed by a local oscillator frequency of the local oscillator signal.

Abstract: A system and methods for electro-optical modulation are presented. A first optical signal and a second optical signal are optically coupled to produce a local oscillator signal propagated in two signal paths. The local oscillator signal in the first signal path and the second signal path is electro-optically phase modulated with a radio frequency electrical signal to produce a first phase modulated optical signal and a second phase modulated optical signal respectively. The first phase modulated optical signal and the second phase modulated optical signal are optically coupled to produce an intensity modulated signal comprising an RF frequency of the radio frequency electrical signal frequency mixed by a local oscillator frequency of the local oscillator signal.

Abstract: Disclosed is a turbocharger with a dual-blade nozzle system, comprising a turbine housing, a fixed nozzle ring (1), a linearly moving nozzle disk (2), a mid-housing (5), a rack (4), rocker arm rods (3), and a gear (6), wherein airfoil-shaped fixed blades (8) are provided on the front end face of the fixed nozzle ring (1), with blade-type holes (9) provided between the fixed blades (8), and the fixed nozzle ring (1) is sheathed around the outside of the mid-housing (5) and fixed to the mid-housing (5) via screws; the linearly moving nozzle disk (2) is provided on the rear end of the fixed nozzle ring (1), a group of moving blades (7) is provided on the front end face of the linearly moving nozzle disk (2), the moving blades (7) are movably inserted into the blade-type holes (9), the rear end face of the linearly moving nozzle disk (2) is fixedly connected to two rocker arm rods (3), with the rocker arm rods (3) inserted into the mid-housing (5) and engaged with the rack (4) via the gear (6).

Abstract: Techniques and devices for depolarizing light and producing a variable differential group delays in optical signals. In one implementation, an input optical beam is split into first and second beams with orthogonal polarizations. One or two optical reflectors are then used to cause the first and second optical beams to undergo different optical path lengths before they are recombined into a single output beam. An adjustment mechanism may used implemented to adjust the difference in the optical path lengths of the first and second beams to produce a variable DGD. When the depolarization of light is desired, the difference in the optical path lengths of the first and second beams is set to be greater than the coherence length of the input optical beam.

Abstract: Techniques and devices for depolarizing light and producing a variable differential group delays in optical signals. In one implementation, an input optical beam is split into first and second beams with orthogonal polarizations. One or two optical reflectors are then used to cause the first and second optical beams to undergo different optical path lengths before they are recombined into a single output beam. An adjustment mechanism may used implemented to adjust the difference in the optical path lengths of the first and second beams to produce a variable DGD. When the depolarization of light is desired, the difference in the optical path lengths of the first and second beams is set to be greater than the coherence length of the input optical beam.

Abstract: Techniques and devices for depolarizing light and producing a variable differential group delays in optical signals. In one implementation, an input optical beam is split into first and second beams with orthogonal polarizations. One or two optical reflectors are then used to cause the first and second optical beams to undergo different optical path lengths before they are recombined into a single output beam. An adjustment mechanism may used implemented to adjust the difference in the optical path lengths of the first and second beams to produce a variable DGD. When the depolarization of light is desired, the difference in the optical path lengths of the first and second beams is set to be greater than the coherence length of the input optical beam.