Patents by Inventor Yongtang Zheng

Yongtang Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • APPLICATION OF NOVEL CORONAVIRUS VACCINE PEPTIDE AND NANOEMULSION PREPARATION THEREOF IN PREVENTION OF NOVEL CORONAVIRUS WILD AND MUTANT STRAINS
    Publication number: 20250009871
    Abstract: Disclosed are an application of a coronavirus SARS-CoV-2 vaccine polypeptide, a polypeptide composition and a nanoemulsion preparation thereof in the prevention of coronavirus SARS-CoV-2 wild and mutant strain infections. Specifically, provided is a coronavirus SARS-CoV-2 vaccine polypeptide having an amino acid sequence derived from an S protein of SARS-CoV-2 wild and mutant strains, the vaccine polypeptide can enable the body to generate high-level and durable humoral immune responses against SARS-CoV-2 and to produce high titers of RBD-binding antibodies and neutralizing antibodies that block the binding of RBD to ACE2. The vaccine polypeptide can be used to prevent infections of SARS-CoV-2 wild strain and B.1.1.7, B.1.351, B.1.617, B.1.1.529 and other mutant strains.
    Type: Application
    Filed: May 30, 2022
    Publication date: January 9, 2025
    Inventors: Likun GONG, Jin REN, Wei HUANG, Yong GAN, Yongtang ZHENG, Jianhua SUN, Xinxin ZHANG, Yiru LONG, Qiuping QIN, Tingting LIU, Feng TANG, Pan YU, Yunqiu MIAO, Yonglong CAI, Mian QIN, Tianzhang SONG
  • METHODS OF USE OF SOLUBLE CD24 FOR TREATING VIRAL PNEUMONIA
    Publication number: 20230108492
    Abstract: Provided is the use of a CD24 protein for treating viral pneumonia.
    Type: Application
    Filed: February 10, 2021
    Publication date: April 6, 2023
    Inventors: Yang Liu, Pan Zheng, Martin Devenport, Renrong Tian, Yongtang Zheng
  • Pyrimidinone-containing compound, preparation method thereof, pharmaceutical composition and application thereof
    Patent number: 11447470
    Abstract: Disclosed is a pyrimidinone-containing compound represented by formula I, a preparation method thereof, a pharmaceutical composition, and an application thereof. The pyrimidinone-containing compound of the present disclosure can be used as HIV-1 inhibitor and can be also used in the treatment of human immunodeficiency virus infection.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: September 20, 2022
    Assignees: Yunnan University, Kunming Institute of Zoology, Chinese Academy of Sciences
    Inventors: Yanping He, Hongbin Zhang, Yongtang Zheng, Yumeng Wu, Chengrun Tang, Ruomei Rui, Liumeng Yang, Jiangyuan Wang
  • DACOS type NNRTIS amino acid ester derivative, preparation method thereof, pharmaceutical composition, and application thereof
    Patent number: 11420959
    Abstract: Disclosed is a DACOs-type NNRTIs amino acid ester derivative, a preparation method thereof, a pharmaceutical composition, and an application thereof. The structure of the DACOs-type NNRTIs amino acid ester derivative is represented by formula (I). The DACOs-type NNRTIs amino acid ester derivative represented by formula (I) can be used as HIV-1 inhibitors and for the preparation of a drug for treating and/or preventing immunodeficiency viruses.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: August 23, 2022
    Assignees: Yunnan University, Kunming Institute of Zoology, Chinese Academy of Sciences
    Inventors: Yanping He, Hongbin Zhang, Yongtang Zheng, Yufang Zhang, Chengrun Tang, Wei Ding, Liumeng Yang, Yiming Li
  • DACOS Type NNRTIS Amino Acid Ester Derivative, Preparation Method Thereof, Pharmaceutical Composition, and Application Thereof
    Publication number: 20210040069
    Abstract: Disclosed is a DACOs-type NNRTIs amino acid ester derivative, a preparation method thereof, a pharmaceutical composition, and an application thereof. The structure of the DACOs-type NNRTIs amino acid ester derivative is represented by formula (I). The DACOs-type NNRTIs amino acid ester derivative represented by formula (I) can be used as HIV-1 inhibitors and for the preparation of a drug for treating and/or preventing immunodeficiency viruses.
    Type: Application
    Filed: March 4, 2019
    Publication date: February 11, 2021
    Inventors: Yanping HE, Hongbin ZHANG, Yongtang ZHENG, Yufang ZHANG, Chengrun TANG, Wei DING, Liumeng YANG, Yiming LI
  • PYRIMIDINONE-CONTAINING COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF
    Publication number: 20200399248
    Abstract: Disclosed is a pyrimidinone-containing compound represented by formula I, a preparation method thereof, a pharmaceutical composition, and an application thereof. The pyrimidinone-containing compound of the present disclosure can be used as HIV-1 inhibitor and can be also used in the treatment of human immunodeficiency virus infection.
    Type: Application
    Filed: March 4, 2019
    Publication date: December 24, 2020
    Inventors: Yanping HE, Hongbin ZHANG, Yongtang ZHENG, Yumeng WU, Chengrun TANG, Ruomei RUI, Liumeng YANG, Jiangyuan WANG
  • 1-(3-aminopropyl) substituted cyclic amine compounds, preparation method therefor, and pharmaceutical compositions and uses thereof
    Patent number: 10167299
    Abstract: Provided are 1-(3-aminopropyl) substituted cyclic amine compounds as represented by frmula (I), pharmaceutically acceptable salts, enantiomers, diastereoisomers, racemates and mixtures thereof, and a method of synthesizing said 1-(3-aminopropyl) substituted cyclic amine compounds by using aromatic heterocyclic formaldehyde as raw material. Said compounds can be used as CCR 5 antagonist for the treatment of HIV infection.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: January 1, 2019
    Assignee: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
    Inventors: Hong Liu, Beili Wu, Yongtang Zheng, Xin Xie, Hualiang Jiang, Panfeng Peng, Ronghua Luo, Jing Li, Jian Li, Ya Zhu, Ying Chen, Haonan Zhang, Liumeng Yang, Yu Zhou, Kaixian Chen
  • 1-(3-AMINOPROPYL) SUBSTITUTED CYCLIC AMINE COMPOUNDS, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
    Publication number: 20170044187
    Abstract: Provided are 1-(3-aminopropyl) substituted cyclic amine compounds as represented by formula (I), pharmaceutically acceptable salts, enantiomers, diastereoisomers, racemates and mixtures thereof, and a method of synthesizing said 1-(3-aminopropyl) substituted cyclic amine compounds by using aromatic heterocyclic formaldehyde as raw material. Said compounds can be used as CCR 5 antagonist for the treatment of HIV infection.
    Type: Application
    Filed: December 29, 2014
    Publication date: February 16, 2017
    Applicant: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
    Inventors: Hong LIU, Beili WU, Yongtang ZHENG, Xin XIE, Hualiang JIANG, Panfeng PENG, Ronghua LUO, Jing LI, Jian LI, Ya ZHU, Ying CHEN, Haonan ZHANG, Liumeng YANG, Yu ZHOU, Kaixian CHEN
  • Nitrogen-containing biphenyl compounds, pharmaceutical compositions of same, preparation methods and anti-HIV-1 uses thereof
    Patent number: 9328084
    Abstract: Nitrogen-containing biphenyl compounds as represented by formula (I), pharmaceutically acceptable salts or derivatives thereof, pharmaceutical compositions, and preparation methods therefore, and anti-HIV-1 use of the compound. Each substituent group in formula (I) is as defined in the description.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: May 3, 2016
    Assignees: Kunming Institute of Botany, The Chinese Academy of Sciences, Yunnan University, Kunming Institute of Zoology, The Chinese Academy of Sciences
    Inventors: Jingping Liu, Handong Sun, Hongbin Zhang, Yongtang Zheng, Weilie Xiao, Jianxin Pu, Ruirui Wang, Liumeng Yang
  • Concentricolide and its derivatives, process for preparing them, pharmaceutical composition comprising the same and its use
    Patent number: 7659308
    Abstract: The present invention relates to concentricolide and its derivatives, a method for the preparation of the compound and its derivatives, a pharmaceutical composition containing concentricolide and its derivatives, and use of the compound and its derivatives for the treatment and prevention of infection caused by human immunodeficiency virus (HIV).
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: February 9, 2010
    Assignees: Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming Institute of Zoology, The Chinese Academy of Sciences
    Inventors: Jikai Liu, Yongtang Zheng, Xiangdong Qin, Liumeng Yang, Zejun Dong, Ruirui Wang, Jianwen Tan
  • Concentricolide and its derivatives, process for preparing them, pharmaceutical composition comprising the same and its use
    Publication number: 20070155830
    Abstract: The present invention relates to concentricolide and its derivatives, a method for the preparation of the compound and its derivatives, a pharmaceutical composition containing concentricolide and its derivatives, and use of the compound and its derivatives for the treatment and prevention of infection caused by human immunodeficiency virus (HIV).
    Type: Application
    Filed: October 20, 2004
    Publication date: July 5, 2007
    Applicants: Kunming Institute of Botany, The Chinese Academy o, Kunming Institute of Zoology, The Chinese Academy
    Inventors: Jikai Liu, Yongtang Zheng, Xiangdong Qin, Liumeng Yang, Zejun Dong, Ruirui Wang, Jianwen Tan