Patents by Inventor Yongtao Xu

Yongtao Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation method of zaleplon
    Patent number: 12195474
    Abstract: A preparation method of zaleplon is provided and belongs to the technical field of pharmaceutical chemistry. The preparation method adopts simple and cheap m-nitrobenzaldehyde and triethylamine as raw materials, and constructs a core structure of zaleplon with high efficiency and high selectivity through a one-pot series reaction without transition metal catalysis, thereby avoiding the formation of isomers, reducing the generation of by-products, increasing the yield of target products and reducing the synthesis cost; and after simple nitro reduction modification, zaleplon is prepared. The method has the advantages of short preparation route, mild reaction conditions and simple operation, so the method is suitable for industrial production.
    Type: Grant
    Filed: January 5, 2022
    Date of Patent: January 14, 2025
    Assignees: Xinxiang Medical College, Anhui University of Technology
    Inventors: Qinghe Gao, Xinya Han, Yongtao Xu, Yingchao Duan, Jieli Lv, Lizhen Fang, Yan Zhang, Jufen Yan, Yingying Li
  • Preparation Method of Zaleplon
    Publication number: 20220259206
    Abstract: A preparation method of zaleplon is provided and belongs to the technical field of pharmaceutical chemistry. The preparation method adopts simple and cheap m-nitrobenzaldehyde and triethylamine as raw materials, and constructs a core structure of zaleplon with high efficiency and high selectivity through a one-pot series reaction without transition metal catalysis, thereby avoiding the formation of isomers, reducing the generation of by-products, increasing the yield of target products and reducing the synthesis cost; and after simple nitro reduction modification, zaleplon is prepared. The method has the advantages of short preparation route, mild reaction conditions and simple operation, so the method is suitable for industrial production.
    Type: Application
    Filed: January 5, 2022
    Publication date: August 18, 2022
    Inventors: Qinghe Gao, Xinya Han, Yongtao Xu, Yingchao Duan, Jieli Lv, Lizhen Fang, Yan Zhang, Jufen Yan, Yingying Li