Patents by Inventor Yongxian Shao

Yongxian Shao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-substituted pyrazolo [3,4-D] pyrimidine ketone compound, and preparation process and use thereof
    Patent number: 9617269
    Abstract: Disclosed are an N-substituted pyrazolo [3,4-d] pyrimidine ketone compound of formula (I), and a preparation process and use thereof as a phosphodiesterase IX (PDEIX) inhibitor: wherein R? is selected from isopropyl, cyclopentyl, cyclohexyl, isobutyl, and o-chlorophenyl; when R??CH3, R represents benzyl; and when R??H, R is selected from 3-methylpyridine, 1-phenylethyl, 1-(4-chlorophenyl)ethyl, D- or L-configured CHCH3CONHR??, D- or L-configured CH2CONHR??, D- or L-configured CH2CH2CONHR??; wherein R1 is selected from hydrogen, chlorine, methoxy, methyl, trifluoromethyl, dimethoxy, methylenedioxy, and dichlorine, and R2 is selected from hydrogen, methoxy, ethoxy, isopropoxy, methyl, dimethoxy, and 2-methyl-4-methoxy, and wherein R?? is p-methoxyphenyl.
    Type: Grant
    Filed: August 2, 2013
    Date of Patent: April 11, 2017
    Assignees: Sun Yat-Sen University, University of North Carolina at Chapel Hill
    Inventors: Haibin Luo, Yiqian Wan, Hengming Ke, Peiqing Liu, Manna Huang, Yongxian Shao, Xinhai Zhu, Yinghong Cai, Yuguo Liu
  • N-SUBSTITUTED PYRAZOLO [3,4-D] PYRIMIDINE KETONE COMPOUND, AND PREPARATION PROCESS AND USE THEREOF
    Publication number: 20150218168
    Abstract: Disclosed are an N-substituted pyrazolo[3,4-d]pyrimidine ketone compound of formula (I), and a preparation process and use thereof as a phosphodiesterase IX (PDEIX) inhibitor: wherein R? is selected from isopropyl, cyclopentyl, cyclohexyl, isobutyl, and o-chlorophenyl; when R??CH3, R represents benzyl; and when R??H, R is selected from 3-methylpyridine, 1-phenylethyl, 1-(4-chlorophenyl)ethyl, D- or L-configured CHCH3CONHR??, D- or L-configured CH2CONHR??, D- or L-configured CH2CH2CONHR??; wherein R1 is selected from hydrogen, chlorine, methoxy, methyl, trifluoromethyl, dimethoxy, methylenedioxy, and dichlorine, and R2 is selected from hydrogen, methoxy, ethoxy, isopropoxy, methyl, dimethoxy, and 2-methyl-4-methoxy, and wherein R?? is p-methoxyphenyl.
    Type: Application
    Filed: August 2, 2013
    Publication date: August 6, 2015
    Inventors: Haibin Luo, Yiqian Wan, Hengming Ke, Peiqing Liu, Manna Huang, Yongxian Shao, Xinhai Zhu, Yinghong Cai, Yuguo Liu