Patents by Inventor Yongxing CAO

Yongxing CAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation method for tyrosine kinase inhibitor and intermediate thereof
    Patent number: 11407734
    Abstract: Provided is a preparation method for a tyrosine kinase inhibitor and an intermediate thereof. Specifically, a preparation method for a cyanoquinoline compound is provided. The method has a high yield, good product purity, and mild reaction conditions.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: August 9, 2022
    Assignee: Jiangsu Hengrui Medicine Co., Ltd.
    Inventors: Guobing Feng, Yongxing Cao, Peng Zhang, Zhenjun Qiu, Long Zhang
  • Method for preparing tyrosine kinase inhibitor and derivative thereof
    Patent number: 11198683
    Abstract: A method for preparing a tyrosine kinase inhibitor and a derivative thereof are described. In particular, the present method has a short synthesis route, low costs, easy operation, and is suitable for large-scale production.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: December 14, 2021
    Assignee: Jiangsu Hengrui Medicine Co., Ltd.
    Inventors: Guaili Wu, Quanliang Zhang, Yongxing Cao
  • CRYSTAL FORM OF MALEATE OF TYROSINE KINASE INHIBITOR AND PREPARATION METHOD THEREFOR
    Publication number: 20210355109
    Abstract: Provided are a crystal form of a maleate of a tyrosine kinase inhibitor and a preparation method therefor. Specifically, provided are I crystal form, a II crystal form, a III crystal form, a IV crystal form and a V crystal form of the compound as shown in formula (I) and a preparation method therefor. The new crystal form has a good stability, thereby making same better to use in clinical treatments.
    Type: Application
    Filed: October 21, 2019
    Publication date: November 18, 2021
    Applicant: JIANGSU HENGRUI MEDICINE CO., LTD.
    Inventors: Zhenjun QIU, Quanliang ZHANG, Yanli WEI, Yongxing CAO, Junran YANG, Yahui MA, Zhenxing DU, Jie WANG
  • METHOD FOR PREPARING TYROSINE KINASE INHIBITOR AND DERIVATIVE THEREOF
    Publication number: 20200392111
    Abstract: A method for preparing a tyrosine kinase inhibitor and a derivative thereof are described. In particular, the present method has a short synthesis route, low costs, easy operation, and is suitable for large-scale production.
    Type: Application
    Filed: August 28, 2020
    Publication date: December 17, 2020
    Inventors: Guaili Wu, Quanliang Zhang, Yongxing Cao
  • Method for preparing tyrosine kinase inhibitor and derivative thereof
    Patent number: 10793548
    Abstract: The present invention relates to a method for preparing a tyrosine kinase inhibitor and a derivative thereof. The present method has a short synthesis route, low costs, easy operation, and is suitable for large-scale production.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: October 6, 2020
    Assignee: Jiangsu Hengrui Medicine Co., Ltd.
    Inventors: Guaili Wu, Quanliang Zhang, Yongxing Cao
  • Preparation Method for Tyrosine Kinase Inhibitor and Intermediate Thereof
    Publication number: 20200239443
    Abstract: Provided is a preparation method for a tyrosine kinase inhibitor and an intermediate thereof. Specifically, a preparation method for a cyanoquinoline compound is provided. The method has a high yield, good product purity, and mild reaction conditions.
    Type: Application
    Filed: October 17, 2018
    Publication date: July 30, 2020
    Inventors: Guobing FENG, Yongxing CAO, Peng ZHANG, Zhenjun QIU, Long ZHANG
  • METHOD FOR PREPARING TYROSINE KINASE INHIBITOR AND DERIVATIVE THEREOF
    Publication number: 20190127350
    Abstract: The present invention relates to a method for preparing a tyrosine kinase inhibitor and a derivative thereof. The present method has a short synthesis route, low costs, easy operation, and is suitable for large-scale production.
    Type: Application
    Filed: April 27, 2017
    Publication date: May 2, 2019
    Inventors: Guaili WU, Quanliang ZHANG, Yongxing CAO