Abstract: A combination drug for treating triple-negative breast cancer. Androgen receptor-targeting degraders (including PROTACs) can effectively prevent and/or treat triple negative breast cancer (including androgen receptor-positive triple negative breast cancer). The combined use of an androgen receptor degrader and a targeting drug (including PI3K? inhibitors and PARP inhibitors), immunotherapy drug or chemotherapy drug can effectively prevent and/or treat triple negative breast cancer.

Abstract: Provided is a drug for treating triple negative breast cancer. Provided is use of an androgen receptor (AR) degrader (including PROTAC) in the preparation of a drug for preventing and/or treating triple negative breast cancer (including androgen receptor positive triple negative breast cancer). Provided is use of an AR degrader in combination with a targeting drug (comprising a PI3K? inhibitor and a PARP inhibitor), an immunotherapy drug or a chemotherapeutic drug in the preparation of a drug for preventing and/or treating triple negative breast cancer.

Abstract: The present invention discloses a positive-pressure double-nozzle nasal cavity cleaner featuring double pressure protection, and relates to the technical field of health care. The nasal cavity cleaner consists of a nose washing end, an upper shell, a core module, a control module, a lower shell, a liquid reservoir and a waste reservoir, wherein the nose washing end is rotatably connected to a top portion of the upper shell, and the nose washing end consists of a silicone washing nozzle, a silicone backflow nozzle and a rotary connecting base. The nasal cavity cleaner uses positive pressure and automatic pressure relief structures to obtain safe and constant air pressure, and then presses normal saline into the nasal cavity to clean the nasal cavity, so that pressure in the nasal cavity is small and stable during cleaning, which prevents damage to the nasal cavity and ear canal, thus being safer to use.

Abstract: The invention provides a calculation method for operating resistance in a dual-electrode DC electric-smelting furnace for magnesium, including the following steps of: calculating a raw material resistance: simplifying a raw material model as an electrode-centered cylindrical model, determining an electric-field strength of each point in an electric field generated by a raw material layer around an electrode in the cylindrical model, calculating a raw material voltage between two electrodes according to the electric-field strength of each point in the electric field, and further obtaining the raw material resistance between the two electrodes; calculating an electric arc-resistance relation model: determining a relation between an actual electric arc length and a distance from the electrode to a surface of a smelting pool, and calculating a relation between an electric arc voltage and the actual electric arc length, namely the electric arc-resistance relation model; and calculating a smelting pool resistance,

Abstract: A rail vehicle lighting device includes: a plurality of short lighting fixtures assembled into a long lighting fixture having a shape matching with a shape of an irregular interior decoration. Each of the short lighting fixtures is provided with a section body. A light source is provided on the section body. The section body is twisted such that included angles between each of the light sources and a horizontal plane are consistent. In the rail vehicle lighting device, the plurality of short lighting fixtures is assembled into the long lighting fixture having the shape matching with the shape of the irregular interior decoration, thereby satisfying a requirement on a shape of a lighting fixture. By arranging the twisted section body, respective points of the long lighting fixture have consistent light source illumination angles, thereby achieving a satisfactory illumination effect inside a carriage having an irregular interior decoration, and accordingly improving the appearance of the carriage.

Abstract: The invention provides a calculation method for operating resistance in a dual-electrode DC electric-smelting furnace for magnesium, including the following steps of: calculating a raw material resistance: simplifying a raw material model as an electrode-centered cylindrical model, determining an electric-field strength of each point in an electric field generated by a raw material layer around an electrode in the cylindrical model, calculating a raw material voltage between two electrodes according to the electric-field strength of each point in the electric field, and further obtaining the raw material resistance between the two electrodes; calculating an electric arc-resistance relation model: determining a relation between an actual electric arc length and a distance from the electrode to a surface of a smelting pool, and calculating a relation between an electric arc voltage and the actual electric arc length, namely the electric arc-resistance relation model; and calculating a smelting pool resistance,

Abstract: A rail vehicle lighting device includes: a plurality of short lighting fixtures assembled into a long lighting fixture having a shape matching with a shape of an irregular interior decoration. Each of the short lighting fixtures is provided with a section body. A light source is provided on the section body. The section body is twisted such that included angles between each of the light sources and a horizontal plane are consistent. In the rail vehicle lighting device, the plurality of short lighting fixtures is assembled into the long lighting fixture having the shape matching with the shape of the irregular interior decoration, thereby satisfying a requirement on a shape of a lighting fixture. By arranging the twisted section body, respective points of the long lighting fixture have consistent light source illumination angles, thereby achieving a satisfactory illumination effect inside a carriage having an irregular interior decoration, and accordingly improving the appearance of the carriage.